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The map label for this gene is trpF [H]

Identifier: 57237402

GI number: 57237402

Start: 355919

End: 356518

Strand: Direct

Name: trpF [H]

Synonym: CJE0396

Alternate gene names: 57237402

Gene position: 355919-356518 (Clockwise)

Preceding gene: 57237401

Following gene: 57237403

Centisome position: 20.02

GC content: 27.33

Gene sequence:

>600_bases
ATGCTAAAGCTTAAAATTTGTGGTATTAAAGATGAAAAAAATGCCAAAGATTTAGCTTTTTTAAATATTGATTTTTTTGG
ACTTATTTTTGCTAAAAGTCCAAGAAGAGTGAGTTTAGAACAAGCAAGAAATTTAAGTGCAATTTTTCATGAAAAAGATA
AAAAAGTTGTCGGTGTTTTTGTAGATGAAAATTTGGAACAAATTTTAAGATGTATTAAAGAAGCTAAGCTTGATGGGATA
CAAATTTATCGCACTATTACCAAAGAAGAATTTGAAATTTTAAAGGTGCAAAATGTTTTTGTTTGGCAGGTGATTAGTGT
GGAAAATAGTTTAGATTTAAAAAGTGAAATTTTTGCTAATTTAGTACTTTTTGATGCTAAGGGAATTTTAAAGGGCGGTA
ATGGAATAAGTTTTGATTGGACTTTATTAGGTTCTTATACTAAAGATTTTATATTAGCCGGAGGCATAGGTTTGGATAAT
GTTCATAAGGCTGTAAAAACGGGAGCTAAAATTTTAGATCTTAATTCAAAACTTGAAGATGAAAAAGGCTTAAAAGATAT
CAACAAAATAAAACAAATTTTAAAGGAGTTGAAAAAATGA

Upstream 100 bases:

>100_bases
ACAGCCAATAAAGCAAGTTCGCCTTTAGTGGCTAAAGATATGATTTTAGAAGCCATTTATTCAGGTAAGGTTATAGAATA
TTTTAAGGAGTATCAAGCTT

Downstream 100 bases:

>100_bases
AAAAAGCGTATTATGGGGATTTTGGTGGGCAGTTTTTGCCTGAAAGTGCAATGTTTGCTTTAAATGAGCTAGAAGGTGCT
TTTTTGAAATTTTCTAAAGA

Product: N-(5'phosphoribosyl)anthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MLKLKICGIKDEKNAKDLAFLNIDFFGLIFAKSPRRVSLEQARNLSAIFHEKDKKVVGVFVDENLEQILRCIKEAKLDGI
QIYRTITKEEFEILKVQNVFVWQVISVENSLDLKSEIFANLVLFDAKGILKGGNGISFDWTLLGSYTKDFILAGGIGLDN
VHKAVKTGAKILDLNSKLEDEKGLKDINKIKQILKELKK

Sequences:

>Translated_199_residues
MLKLKICGIKDEKNAKDLAFLNIDFFGLIFAKSPRRVSLEQARNLSAIFHEKDKKVVGVFVDENLEQILRCIKEAKLDGI
QIYRTITKEEFEILKVQNVFVWQVISVENSLDLKSEIFANLVLFDAKGILKGGNGISFDWTLLGSYTKDFILAGGIGLDN
VHKAVKTGAKILDLNSKLEDEKGLKDINKIKQILKELKK
>Mature_199_residues
MLKLKICGIKDEKNAKDLAFLNIDFFGLIFAKSPRRVSLEQARNLSAIFHEKDKKVVGVFVDENLEQILRCIKEAKLDGI
QIYRTITKEEFEILKVQNVFVWQVISVENSLDLKSEIFANLVLFDAKGILKGGNGISFDWTLLGSYTKDFILAGGIGLDN
VHKAVKTGAKILDLNSKLEDEKGLKDINKIKQILKELKK

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=199, Percent_Identity=30.1507537688442, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 22482; Mature: 22482

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLKICGIKDEKNAKDLAFLNIDFFGLIFAKSPRRVSLEQARNLSAIFHEKDKKVVGVF
CEEEEEECCCCCCCCCCEEEEEEHHEEEEEECCCCEECHHHHCCHHHHHCCCCCEEEEEE
VDENLEQILRCIKEAKLDGIQIYRTITKEEFEILKVQNVFVWQVISVENSLDLKSEIFAN
ECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCEEEEEEEECCCCCCHHHHHHHH
LVLFDAKGILKGGNGISFDWTLLGSYTKDFILAGGIGLDNVHKAVKTGAKILDLNSKLED
HHEEECCCEEECCCCCEEEEEEECCCCCHHEEECCCCHHHHHHHHHCCCEEEECCCCCCH
EKGLKDINKIKQILKELKK
HCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKLKICGIKDEKNAKDLAFLNIDFFGLIFAKSPRRVSLEQARNLSAIFHEKDKKVVGVF
CEEEEEECCCCCCCCCCEEEEEEHHEEEEEECCCCEECHHHHCCHHHHHCCCCCEEEEEE
VDENLEQILRCIKEAKLDGIQIYRTITKEEFEILKVQNVFVWQVISVENSLDLKSEIFAN
ECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCEEEEEEEECCCCCCHHHHHHHH
LVLFDAKGILKGGNGISFDWTLLGSYTKDFILAGGIGLDNVHKAVKTGAKILDLNSKLED
HHEEECCCEEECCCCCEEEEEEECCCCCHHEEECCCCHHHHHHHHHCCCEEEECCCCCCH
EKGLKDINKIKQILKELKK
HCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA