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The map label for this gene is fabH [H]

Identifier: 57237379

GI number: 57237379

Start: 334717

End: 335691

Strand: Reverse

Name: fabH [H]

Synonym: CJE0373

Alternate gene names: 57237379

Gene position: 335691-334717 (Counterclockwise)

Preceding gene: 57237380

Following gene: 57237361

Centisome position: 18.88

GC content: 34.15

Gene sequence:

>975_bases
ATGCTTAAAGCCGGTCTTAAAAGTATAGCTTCTTATATTCCAGAAAAAATTTTAAGCAATGCTGATCTTGAAAAAATAGT
AGATACCACCGATGAATGGATCACTAGACGCACAGGTATTAAAGAAAGACGCATTGCTAGTGAAAATGAAAATTCTAGCG
ATTTGGGCACAAAAGCTGCATTAAAAGCCATAGAAAGAGCAAATTTAAAACCTGAAGATATTGATGCGATTCTTGTAGCC
ACTTTAAGTCCTGATTATTTTACTATGCCTTCAACGGCTTGTAAAATTGCTTCAAATTTAGGACTTGTAAATATTAGTGC
TTTTGATATTTCAGCAGCTTGTTCTGGTTTTATCTATTTGCTTGAACAAGCTAAAGCCTTAGTAGAAAGTGGTTTGAAAA
AAAATGTTTTAATCGTAGGAGCTGAAAAAACAAGTTCAATTATGGATTACAATGACAGAAGCATTTGCATACTCTTTGGA
GACGGTGCGGGTGCTGGAGTTGTAAGTTTGGACAATGAAAATCATATCCTTGATGTACATACTGCAAGCAATGGTAATTA
TGGAGATCTTTTAATGACTCAAAGATCGCAAAAATCAAGTCTATGTCAAACACTTTCTATGCAAATGAAAGGCAATGAAG
TTTTTAAAATAGCAGTAAACACGCTTAGCAATGATGTTGTAGAAATTTTAGCTAAAAATAACATTTTAGCACAAGAAATT
GATCTTTTTATTCCTCATCAAGCTAATCTACGCATCATTAAAGCCGTCCAAGAAAAACTCAATCTAAGCGATGAAAAATG
TGTGATTACCGTACAAAAATATGGCAATACTTCAGCTGCTTCTATACCTATGGCAATGAATGATGCCTATGAAGAAGGAC
GACTTAAAAAAGGAAATCTGATCTTACTAGATGCTTTTGGCGGTGGTTTTACTTGGGGATCTGCGCTTTTAAAATTTGGA
GGAGAGAATTTTTAA

Upstream 100 bases:

>100_bases
AAAAGTGATTCTAGAGCTATTAAAAATGCAATTTTTCAAGCTATAAATTTTAGCCAATCTCATATCAATGAACTTATAGA
AAATGAACTTGGGAAATACA

Downstream 100 bases:

>100_bases
TTCTCTCTTAGCTTTCCAAAAGCTTGAATTTCTACCAAATAACCCTCTGCTAAAGCACTTCCTACACAAGCTCTAACAGG
TTTAGGATAATTTTTAATCC

Product: 3-oxoacyl-ACP synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MLKAGLKSIASYIPEKILSNADLEKIVDTTDEWITRRTGIKERRIASENENSSDLGTKAALKAIERANLKPEDIDAILVA
TLSPDYFTMPSTACKIASNLGLVNISAFDISAACSGFIYLLEQAKALVESGLKKNVLIVGAEKTSSIMDYNDRSICILFG
DGAGAGVVSLDNENHILDVHTASNGNYGDLLMTQRSQKSSLCQTLSMQMKGNEVFKIAVNTLSNDVVEILAKNNILAQEI
DLFIPHQANLRIIKAVQEKLNLSDEKCVITVQKYGNTSAASIPMAMNDAYEEGRLKKGNLILLDAFGGGFTWGSALLKFG
GENF

Sequences:

>Translated_324_residues
MLKAGLKSIASYIPEKILSNADLEKIVDTTDEWITRRTGIKERRIASENENSSDLGTKAALKAIERANLKPEDIDAILVA
TLSPDYFTMPSTACKIASNLGLVNISAFDISAACSGFIYLLEQAKALVESGLKKNVLIVGAEKTSSIMDYNDRSICILFG
DGAGAGVVSLDNENHILDVHTASNGNYGDLLMTQRSQKSSLCQTLSMQMKGNEVFKIAVNTLSNDVVEILAKNNILAQEI
DLFIPHQANLRIIKAVQEKLNLSDEKCVITVQKYGNTSAASIPMAMNDAYEEGRLKKGNLILLDAFGGGFTWGSALLKFG
GENF
>Mature_324_residues
MLKAGLKSIASYIPEKILSNADLEKIVDTTDEWITRRTGIKERRIASENENSSDLGTKAALKAIERANLKPEDIDAILVA
TLSPDYFTMPSTACKIASNLGLVNISAFDISAACSGFIYLLEQAKALVESGLKKNVLIVGAEKTSSIMDYNDRSICILFG
DGAGAGVVSLDNENHILDVHTASNGNYGDLLMTQRSQKSSLCQTLSMQMKGNEVFKIAVNTLSNDVVEILAKNNILAQEI
DLFIPHQANLRIIKAVQEKLNLSDEKCVITVQKYGNTSAASIPMAMNDAYEEGRLKKGNLILLDAFGGGFTWGSALLKFG
GENF

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=309, Percent_Identity=48.2200647249191, Blast_Score=308, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 35090; Mature: 35090

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKAGLKSIASYIPEKILSNADLEKIVDTTDEWITRRTGIKERRIASENENSSDLGTKAA
CCCHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHH
LKAIERANLKPEDIDAILVATLSPDYFTMPSTACKIASNLGLVNISAFDISAACSGFIYL
HHHHHHCCCCCCCCCEEEEEEECCCCEECCHHHHHHHHCCCEEEEEEECHHHHHHHHHHH
LEQAKALVESGLKKNVLIVGAEKTSSIMDYNDRSICILFGDGAGAGVVSLDNENHILDVH
HHHHHHHHHCCCCCCEEEEECCCCCHHHCCCCCEEEEEEECCCCCCEEEECCCCCEEEEE
TASNGNYGDLLMTQRSQKSSLCQTLSMQMKGNEVFKIAVNTLSNDVVEILAKNNILAQEI
ECCCCCCCCEEEECCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHCCCEEEEHH
DLFIPHQANLRIIKAVQEKLNLSDEKCVITVQKYGNTSAASIPMAMNDAYEEGRLKKGNL
CEECCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCHHHCHHHCCCCCCCCE
ILLDAFGGGFTWGSALLKFGGENF
EEEECCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLKAGLKSIASYIPEKILSNADLEKIVDTTDEWITRRTGIKERRIASENENSSDLGTKAA
CCCHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHH
LKAIERANLKPEDIDAILVATLSPDYFTMPSTACKIASNLGLVNISAFDISAACSGFIYL
HHHHHHCCCCCCCCCEEEEEEECCCCEECCHHHHHHHHCCCEEEEEEECHHHHHHHHHHH
LEQAKALVESGLKKNVLIVGAEKTSSIMDYNDRSICILFGDGAGAGVVSLDNENHILDVH
HHHHHHHHHCCCCCCEEEEECCCCCHHHCCCCCEEEEEEECCCCCCEEEECCCCCEEEEE
TASNGNYGDLLMTQRSQKSSLCQTLSMQMKGNEVFKIAVNTLSNDVVEILAKNNILAQEI
ECCCCCCCCEEEECCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHCCCEEEEHH
DLFIPHQANLRIIKAVQEKLNLSDEKCVITVQKYGNTSAASIPMAMNDAYEEGRLKKGNL
CEECCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCHHHCHHHCCCCCCCCE
ILLDAFGGGFTWGSALLKFGGENF
EEEECCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA