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The map label for this gene is serC [H]

Identifier: 57237377

GI number: 57237377

Start: 333297

End: 334373

Strand: Direct

Name: serC [H]

Synonym: CJE0371

Alternate gene names: 57237377

Gene position: 333297-334373 (Clockwise)

Preceding gene: 57237376

Following gene: 57237378

Centisome position: 18.75

GC content: 31.29

Gene sequence:

>1077_bases
ATGAGAAAAATCAATTTCAGTGCAGGGCCATCGACTTTACCTTTAGAAATTTTAGAGCAAGCTCAAAAAGAACTCTGTGA
TTATCAGGGTAGGGGTTATTCTATAATGGAAATTTCTCACCGCACAAAAGTATTTGAAGAAGTGCATTTTGGAGCACAAG
AGAAAGCTAAAAAACTTTACGGGTTAAATGATGATTATGAAGTATTATTTTTACAAGGTGGAGCAAGTTTACAATTTGCT
ATGATTCCTATGAATTTGGCTTTAAATGGGATTTGTGAATATGCAAATACAGGAGTTTGGACAAAAAAAGCAATTAAAGA
AGCACAAATTTTAGGTGTCAATGTTAAAACCGTAGCAAGTAGCGAGGAAAGTAATTTTAATCATATTCCTAGAGTGGAAT
TTAGAGATAATGCTGATTATGCTTATATTTGTTCTAACAATACTATTTATGGCACTCAATATCAAAATTATCCTAAAACT
AAAACTCCTTTGATTGTGGATGCATCGAGTGATTTTTTTTCTAGAAAAGTAGATTTTTCAAATATTGCTCTTTTTTATGG
CGGAGTGCAAAAAAATGCTGGAATTTCGGGTTTAAGTTGTATTTTTATCCGTAAAGATATGTTAGAAAGATCTAAAAATA
AACAAATTCCTAGTATGTTAAATTATTTGACTCATGCTGAGAATCAGTCCTTGTTTAATACGCCTCCAACCTTTGCCATT
TATATGTTTATTCTTGAAATGGATTGGCTTTTAAATCAAGGCGGACTTGATAAAGTACATGAGAAAAATTCTCAAAAAGC
TGCTATGCTTTATGAGTGTATTGATTTAAGTAATGGATTTTATAAAGGACATGCAGATAAAAAGGACAGATCTTTAATGA
ATGTGAGTTTTAATATTGCTAAAAATAAAGATTTAGAGCCTCTTTTTGTAAAGGAAGCCGAAGAAGCTGGAATGATAGGA
CTTAAAGGACATAGAATTTTAGGAGGAATTCGTGCAAGTATTTATAATGCGCTTAATTTGGATCAGGTAAAAACCTTGTG
TGAATTTATGAAAGAATTTCAAGGAAAATATGCATGA

Upstream 100 bases:

>100_bases
TGGTAAAATAGCAAATTTAGAAGATCTTAAGAGTGATGATATCGTTATTTTAAGTTCTCAAACTTCTCAAAAAGAAGCAA
AAATTTTATAAGGATAGATT

Downstream 100 bases:

>100_bases
TAAAGCGTTTTGATGAGTGCGATAGAATGTCGCAAATTATTGTTTTTGATAAATATTTTAAGACTGCAGGACAAGTGGCT
TTTGAACCTAGCGGAGATAT

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MRKINFSAGPSTLPLEILEQAQKELCDYQGRGYSIMEISHRTKVFEEVHFGAQEKAKKLYGLNDDYEVLFLQGGASLQFA
MIPMNLALNGICEYANTGVWTKKAIKEAQILGVNVKTVASSEESNFNHIPRVEFRDNADYAYICSNNTIYGTQYQNYPKT
KTPLIVDASSDFFSRKVDFSNIALFYGGVQKNAGISGLSCIFIRKDMLERSKNKQIPSMLNYLTHAENQSLFNTPPTFAI
YMFILEMDWLLNQGGLDKVHEKNSQKAAMLYECIDLSNGFYKGHADKKDRSLMNVSFNIAKNKDLEPLFVKEAEEAGMIG
LKGHRILGGIRASIYNALNLDQVKTLCEFMKEFQGKYA

Sequences:

>Translated_358_residues
MRKINFSAGPSTLPLEILEQAQKELCDYQGRGYSIMEISHRTKVFEEVHFGAQEKAKKLYGLNDDYEVLFLQGGASLQFA
MIPMNLALNGICEYANTGVWTKKAIKEAQILGVNVKTVASSEESNFNHIPRVEFRDNADYAYICSNNTIYGTQYQNYPKT
KTPLIVDASSDFFSRKVDFSNIALFYGGVQKNAGISGLSCIFIRKDMLERSKNKQIPSMLNYLTHAENQSLFNTPPTFAI
YMFILEMDWLLNQGGLDKVHEKNSQKAAMLYECIDLSNGFYKGHADKKDRSLMNVSFNIAKNKDLEPLFVKEAEEAGMIG
LKGHRILGGIRASIYNALNLDQVKTLCEFMKEFQGKYA
>Mature_358_residues
MRKINFSAGPSTLPLEILEQAQKELCDYQGRGYSIMEISHRTKVFEEVHFGAQEKAKKLYGLNDDYEVLFLQGGASLQFA
MIPMNLALNGICEYANTGVWTKKAIKEAQILGVNVKTVASSEESNFNHIPRVEFRDNADYAYICSNNTIYGTQYQNYPKT
KTPLIVDASSDFFSRKVDFSNIALFYGGVQKNAGISGLSCIFIRKDMLERSKNKQIPSMLNYLTHAENQSLFNTPPTFAI
YMFILEMDWLLNQGGLDKVHEKNSQKAAMLYECIDLSNGFYKGHADKKDRSLMNVSFNIAKNKDLEPLFVKEAEEAGMIG
LKGHRILGGIRASIYNALNLDQVKTLCEFMKEFQGKYA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=360, Percent_Identity=38.8888888888889, Blast_Score=262, Evalue=3e-70,
Organism=Homo sapiens, GI10863955, Length=357, Percent_Identity=33.6134453781513, Blast_Score=214, Evalue=1e-55,
Organism=Escherichia coli, GI1787136, Length=359, Percent_Identity=41.5041782729805, Blast_Score=261, Evalue=4e-71,
Organism=Caenorhabditis elegans, GI17506897, Length=364, Percent_Identity=40.6593406593407, Blast_Score=268, Evalue=5e-72,
Organism=Saccharomyces cerevisiae, GI6324758, Length=387, Percent_Identity=33.8501291989664, Blast_Score=221, Evalue=1e-58,
Organism=Drosophila melanogaster, GI21356589, Length=359, Percent_Identity=38.7186629526462, Blast_Score=254, Evalue=6e-68,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40466; Mature: 40466

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKINFSAGPSTLPLEILEQAQKELCDYQGRGYSIMEISHRTKVFEEVHFGAQEKAKKLY
CCEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCHHHHHHHHC
GLNDDYEVLFLQGGASLQFAMIPMNLALNGICEYANTGVWTKKAIKEAQILGVNVKTVAS
CCCCCCEEEEEECCCCEEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHEEECEEEEEEC
SEESNFNHIPRVEFRDNADYAYICSNNTIYGTQYQNYPKTKTPLIVDASSDFFSRKVDFS
CCCCCCCCCCCEEEECCCCEEEEECCCEEECCCCCCCCCCCCCEEEECCCCHHHCCCCCC
NIALFYGGVQKNAGISGLSCIFIRKDMLERSKNKQIPSMLNYLTHAENQSLFNTPPTFAI
EEEEEECCCCCCCCCCCEEEEEEEHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHH
YMFILEMDWLLNQGGLDKVHEKNSQKAAMLYECIDLSNGFYKGHADKKDRSLMNVSFNIA
HHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEEEEE
KNKDLEPLFVKEAEEAGMIGLKGHRILGGIRASIYNALNLDQVKTLCEFMKEFQGKYA
CCCCCCCCEEECHHHCCEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRKINFSAGPSTLPLEILEQAQKELCDYQGRGYSIMEISHRTKVFEEVHFGAQEKAKKLY
CCEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCHHHHHHHHC
GLNDDYEVLFLQGGASLQFAMIPMNLALNGICEYANTGVWTKKAIKEAQILGVNVKTVAS
CCCCCCEEEEEECCCCEEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHEEECEEEEEEC
SEESNFNHIPRVEFRDNADYAYICSNNTIYGTQYQNYPKTKTPLIVDASSDFFSRKVDFS
CCCCCCCCCCCEEEECCCCEEEEECCCEEECCCCCCCCCCCCCEEEECCCCHHHCCCCCC
NIALFYGGVQKNAGISGLSCIFIRKDMLERSKNKQIPSMLNYLTHAENQSLFNTPPTFAI
EEEEEECCCCCCCCCCCEEEEEEEHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHH
YMFILEMDWLLNQGGLDKVHEKNSQKAAMLYECIDLSNGFYKGHADKKDRSLMNVSFNIA
HHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEEEEE
KNKDLEPLFVKEAEEAGMIGLKGHRILGGIRASIYNALNLDQVKTLCEFMKEFQGKYA
CCCCCCCCEEECHHHCCEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA