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The map label for this gene is serB [C]

Identifier: 57237337

GI number: 57237337

Start: 296067

End: 296690

Strand: Reverse

Name: serB [C]

Synonym: CJE0330

Alternate gene names: 57237337

Gene position: 296690-296067 (Counterclockwise)

Preceding gene: 57237338

Following gene: 57237336

Centisome position: 16.69

GC content: 32.05

Gene sequence:

>624_bases
ATGATTAAACTTTGTGTTTTTGACTTTGATGCTACTTTAATGGATGGTGAAACCATCGATATTTTAGCTACAGCGCATGG
CAAGGGTAATCAAACAAGCGAAATTACCCGCCATGCTATGACTGGAGAACTTGATTTTTTCGAAAGTCTTCAAAAACGAG
TAAGCTTTTTAAAAGGTATGTCTTATAAAAAAGTTTTAGAATTAAGTAGCACACTTCCACTAATGCGTGGAGCACATGAA
CTTATCCAATATTTAAAATCTAAAAATATACAAATTGTTATTTTTAGCGGTGGTTTTCATGAAGGCATAAATCCTGCTAT
GCAAAAACTTGGAATTAACCTCGGTTTTGCAAATTATCTGCATCATAAAAATGACATTTTAACAGGGCTAGTTGGTGGGG
AAATGATGTTTTCAAATTCAAAAGGCTTAATGCTACAACGATTAAAAAGCTTTTTAAATTTGAAAACAGATGAAGTGATG
TGTGTTGGCGATGGGGCAAATGATTTGGCAATGTTTAACGAAAGTGGATTAAAGATTGCATTTTGTGCTAAAGAAATTTT
ACGTTCTCAAGCTGATATTTGCATAGATATAAAAGACTTAAAAGAAATAATAAAGGTAATATAA

Upstream 100 bases:

>100_bases
CTTTAGTTAAAGACAAAGGTATGATTTATGGTATAGGAAAAAGAGATGAAAATATCTTAACTATACTCAAAGTAGAAGCT
TTGCTTAAGCGCGAATTTTA

Downstream 100 bases:

>100_bases
TGAAAAATTTTTCTCTTTGGTGTGATTTTATAGAAAATAGTTTTTTAGATAATGAATTTTTAAATTTATTATCACATGGA
ATTAATGGCGCTACTTCAAA

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MIKLCVFDFDATLMDGETIDILATAHGKGNQTSEITRHAMTGELDFFESLQKRVSFLKGMSYKKVLELSSTLPLMRGAHE
LIQYLKSKNIQIVIFSGGFHEGINPAMQKLGINLGFANYLHHKNDILTGLVGGEMMFSNSKGLMLQRLKSFLNLKTDEVM
CVGDGANDLAMFNESGLKIAFCAKEILRSQADICIDIKDLKEIIKVI

Sequences:

>Translated_207_residues
MIKLCVFDFDATLMDGETIDILATAHGKGNQTSEITRHAMTGELDFFESLQKRVSFLKGMSYKKVLELSSTLPLMRGAHE
LIQYLKSKNIQIVIFSGGFHEGINPAMQKLGINLGFANYLHHKNDILTGLVGGEMMFSNSKGLMLQRLKSFLNLKTDEVM
CVGDGANDLAMFNESGLKIAFCAKEILRSQADICIDIKDLKEIIKVI
>Mature_207_residues
MIKLCVFDFDATLMDGETIDILATAHGKGNQTSEITRHAMTGELDFFESLQKRVSFLKGMSYKKVLELSSTLPLMRGAHE
LIQYLKSKNIQIVIFSGGFHEGINPAMQKLGINLGFANYLHHKNDILTGLVGGEMMFSNSKGLMLQRLKSFLNLKTDEVM
CVGDGANDLAMFNESGLKIAFCAKEILRSQADICIDIKDLKEIIKVI

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=190, Percent_Identity=31.0526315789474, Blast_Score=71, Evalue=8e-13,
Organism=Escherichia coli, GI1790849, Length=197, Percent_Identity=35.5329949238579, Blast_Score=110, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6321647, Length=207, Percent_Identity=33.8164251207729, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 23010; Mature: 23010

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLCVFDFDATLMDGETIDILATAHGKGNQTSEITRHAMTGELDFFESLQKRVSFLKGM
CEEEEEEECCCEEECCCEEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
SYKKVLELSSTLPLMRGAHELIQYLKSKNIQIVIFSGGFHEGINPAMQKLGINLGFANYL
CHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHCCCCCHHHHH
HHKNDILTGLVGGEMMFSNSKGLMLQRLKSFLNLKTDEVMCVGDGANDLAMFNESGLKIA
HCCHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEECCCCCEEH
FCAKEILRSQADICIDIKDLKEIIKVI
HHHHHHHHCCCCEEEEHHHHHHHHHHC
>Mature Secondary Structure
MIKLCVFDFDATLMDGETIDILATAHGKGNQTSEITRHAMTGELDFFESLQKRVSFLKGM
CEEEEEEECCCEEECCCEEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
SYKKVLELSSTLPLMRGAHELIQYLKSKNIQIVIFSGGFHEGINPAMQKLGINLGFANYL
CHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHCCCCCHHHHH
HHKNDILTGLVGGEMMFSNSKGLMLQRLKSFLNLKTDEVMCVGDGANDLAMFNESGLKIA
HCCHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEECCCCCEEH
FCAKEILRSQADICIDIKDLKEIIKVI
HHHHHHHHCCCCEEEEHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 11342136; 12051918 [H]