Click here to switch to the map view.

The map label for this gene is ilvE [H]

Identifier: 57237325

GI number: 57237325

Start: 283970

End: 284884

Strand: Reverse

Name: ilvE [H]

Synonym: CJE0318

Alternate gene names: 57237325

Gene position: 284884-283970 (Counterclockwise)

Preceding gene: 57237336

Following gene: 57237324

Centisome position: 16.02

GC content: 33.77

Gene sequence:

>915_bases
ATGATCTCAGCAGATAAAATTTGGATGGATGGAAAATTAGTTGATTTTAAAGATGCAACTTTGCACTTTTTAACCCATTC
TTTGCATTATGGCAATGCTGTTTTTGAAGGAACTAGAGCCTATAAAACAGATAAAGGCTTGGCAATTTTCAGACTTGAAG
ATCACACCAAAAGACTTTTAGAGTCTGCAAAAATTACTCTTTTAAATTGTCCTTTTTCCCAAAAAGAGCTTGAAAATGCA
CAAATTGAACTCTTAAAAGCAAACAACTTTAAAAGCAATGTCTATATCCGCCCTTTGATTTTCTTAGGCGATGGAGTTAT
GGGACTTTATCATATAAAAGCTCCTGTAAGAGTTGGAATTGCAGCTTGGGAATGGGGTGCTTACCTTGGAGAAGAAGGTT
TAGAAAAAGGCATAAAAGTAAAAATTTCGTCTTTTGCAAGAAATAGTGTTAAGTCATGCATGGGAAAAGCTAAAGCAAGT
GCAAATTATCTTAACTCTCAAATTGCAAAATTTGAAGCTATTGAAGCAGGCTATGAAGAAGCTTTAATGCTTGATGAAGA
AGGTTTTATCGCAGAAGGAACAGGAGAATGTTTCTTTATTGTAAAAGACGGGGTTTTAATCACACCTCCAAATGATTTTT
CTTTAAAAAGCATTACTCAAAATACAGTGCTTAAAATAGCTCATGATCTTGGTATCACTGTGCTTCGCCAAAGAATTTCA
AGAGATGAAGTTTATACTGCTGATGAAGCATTTTTTACCGGAACAGCCGCTGAAATCACACCTATTAACAATATTGATGC
AAGAATAATAGGAAATGGTTTAAGAGGATCTGTAACTAAAAAACTTCAAGATGCTTATTTTGATGTAGTTTATGGACGCA
ATGAAAAATACGCATCTATGCTAACTTATATTTAA

Upstream 100 bases:

>100_bases
AATTTAATAAAAGCTTATTGTTAGTATATTTTTGATAAAATCCCGATTTATTCTTAAAATAATATTTTTTAAGAAATAAA
CAACTATAAAAGGTAAAAAA

Downstream 100 bases:

>100_bases
AAAAGGAAATAAATGCCAGCTGATTTAAATGATTATTTCAATAAAAAAAATAGAAATTCTAACAATAACGGAAACAACAA
CCGTCAAAATTTCAATTTCA

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MISADKIWMDGKLVDFKDATLHFLTHSLHYGNAVFEGTRAYKTDKGLAIFRLEDHTKRLLESAKITLLNCPFSQKELENA
QIELLKANNFKSNVYIRPLIFLGDGVMGLYHIKAPVRVGIAAWEWGAYLGEEGLEKGIKVKISSFARNSVKSCMGKAKAS
ANYLNSQIAKFEAIEAGYEEALMLDEEGFIAEGTGECFFIVKDGVLITPPNDFSLKSITQNTVLKIAHDLGITVLRQRIS
RDEVYTADEAFFTGTAAEITPINNIDARIIGNGLRGSVTKKLQDAYFDVVYGRNEKYASMLTYI

Sequences:

>Translated_304_residues
MISADKIWMDGKLVDFKDATLHFLTHSLHYGNAVFEGTRAYKTDKGLAIFRLEDHTKRLLESAKITLLNCPFSQKELENA
QIELLKANNFKSNVYIRPLIFLGDGVMGLYHIKAPVRVGIAAWEWGAYLGEEGLEKGIKVKISSFARNSVKSCMGKAKAS
ANYLNSQIAKFEAIEAGYEEALMLDEEGFIAEGTGECFFIVKDGVLITPPNDFSLKSITQNTVLKIAHDLGITVLRQRIS
RDEVYTADEAFFTGTAAEITPINNIDARIIGNGLRGSVTKKLQDAYFDVVYGRNEKYASMLTYI
>Mature_304_residues
MISADKIWMDGKLVDFKDATLHFLTHSLHYGNAVFEGTRAYKTDKGLAIFRLEDHTKRLLESAKITLLNCPFSQKELENA
QIELLKANNFKSNVYIRPLIFLGDGVMGLYHIKAPVRVGIAAWEWGAYLGEEGLEKGIKVKISSFARNSVKSCMGKAKAS
ANYLNSQIAKFEAIEAGYEEALMLDEEGFIAEGTGECFFIVKDGVLITPPNDFSLKSITQNTVLKIAHDLGITVLRQRIS
RDEVYTADEAFFTGTAAEITPINNIDARIIGNGLRGSVTKKLQDAYFDVVYGRNEKYASMLTYI

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI50658084, Length=293, Percent_Identity=26.2798634812287, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI48994963, Length=297, Percent_Identity=45.4545454545455, Blast_Score=254, Evalue=4e-69,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 33857; Mature: 33857

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISADKIWMDGKLVDFKDATLHFLTHSLHYGNAVFEGTRAYKTDKGLAIFRLEDHTKRLL
CCCCCEEEECCEEEECCCHHHHHHHHHHHCCCEEECCCCCEECCCCEEEEEECHHHHHHH
ESAKITLLNCPFSQKELENAQIELLKANNFKSNVYIRPLIFLGDGVMGLYHIKAPVRVGI
HCCCEEEEECCCCHHHHCCCEEEEEEECCCCCCEEEEEEEEECCCCEEEEEECCCCEEEE
AAWEWGAYLGEEGLEKGIKVKISSFARNSVKSCMGKAKASANYLNSQIAKFEAIEAGYEE
EEEHHHHHHCHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ALMLDEEGFIAEGTGECFFIVKDGVLITPPNDFSLKSITQNTVLKIAHDLGITVLRQRIS
EEEECCCCCEECCCCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
RDEVYTADEAFFTGTAAEITPINNIDARIIGNGLRGSVTKKLQDAYFDVVYGRNEKYASM
CCCEEECCCCEEECCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHEEEEECCCCHHHHH
LTYI
HHCC
>Mature Secondary Structure
MISADKIWMDGKLVDFKDATLHFLTHSLHYGNAVFEGTRAYKTDKGLAIFRLEDHTKRLL
CCCCCEEEECCEEEECCCHHHHHHHHHHHCCCEEECCCCCEECCCCEEEEEECHHHHHHH
ESAKITLLNCPFSQKELENAQIELLKANNFKSNVYIRPLIFLGDGVMGLYHIKAPVRVGI
HCCCEEEEECCCCHHHHCCCEEEEEEECCCCCCEEEEEEEEECCCCEEEEEECCCCEEEE
AAWEWGAYLGEEGLEKGIKVKISSFARNSVKSCMGKAKASANYLNSQIAKFEAIEAGYEE
EEEHHHHHHCHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ALMLDEEGFIAEGTGECFFIVKDGVLITPPNDFSLKSITQNTVLKIAHDLGITVLRQRIS
EEEECCCCCEECCCCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
RDEVYTADEAFFTGTAAEITPINNIDARIIGNGLRGSVTKKLQDAYFDVVYGRNEKYASM
CCCEEECCCCEEECCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHEEEEECCCCHHHHH
LTYI
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]