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The map label for this gene is argD [H]

Identifier: 57237287

GI number: 57237287

Start: 246880

End: 248061

Strand: Direct

Name: argD [H]

Synonym: CJE0278

Alternate gene names: 57237287

Gene position: 246880-248061 (Clockwise)

Preceding gene: 57237286

Following gene: 57237289

Centisome position: 13.89

GC content: 32.91

Gene sequence:

>1182_bases
ATGGATTATAAAGAACAAAGTCATATTGTCCCTACTTATAAGCGTTTTGATATAGTTTTAGAAAAAGGGCAGGGGGTTTA
TCTTTTTGATGATAAGGCTAAAAAATATCTTGATTTTTCAAGTGGTATAGGTGTTTGTGCTTTAGGATATAATCATGCTA
AATTTAATGCTAAAATCAAAGCTCAAGTGGATAAACTTTTACATACTAGCAATTTATATTATAATGAAAACATAGCCGCT
GCAGCTAAAAATTTAGCCAAAGCTAGTGCTTTAGAGCGTGTTTTTTTTACAAATTCTGGTACAGAAAGTATAGAAGGAGC
GATGAAAACAGCTAGAAAATACGCCTTTAACAAAGGTATTAAGGGTGGACAATTTATCGCTTTTAAGCATTCTTTTCATG
GGCGTACTTTAGGGGCTTTATCGCTTACTGCTAATGAAAAATATCAAAAGCCTTTTAAACCTTTAATTTCAGGGGTTAAA
TTTGCAAAATATAATGATATTTTAAGCGTTGAAAAACTGGTGAATGAAAAAACTTGTGCCATTATCTTAGAAAGCGTGCA
AGGAGAAGGTGGGATAAATCCTGCAAATAAAGATTTTTACAAAGCCTTAAGAAAGCTTTGCGATGAAAAAGATATATTAT
TAATCGCTGATGAAATTCAATGTGGCATGGGTAGAAGTGGAAAATTTTTTGCCTATGAGCACGCACAAATTTTGCCTGAT
ATCATGACTTCAGCTAAGGCCTTAGGTTGTGGGCTTAGTGTGGGTGCTTTTGTAATAAATCAAAAGGTAGCAAGCAATTC
TTTAGAAGCAGGCGATCATGGTAGTACTTATGGTGGAAATCCTTTAGTTTGTGCAGGAGTGAATGCAGTTTTTGAAATTT
TTAAAGAAGAAAAAATTTTAGAAAATGTCAATAAACTCACGCCTTATTTAGAGCAAAGTTTAGATGAGTTGATAAATGAA
TTTGATTTTTGTAAAAAACGCAAAGGCTTAGGGTTTATGCAAGGGCTGAGTCTTGATAAAAATGTAAAAGTAGCTAAGGT
CATTCAAAAATGCCAAGAAAATGCACTTTTACTGATAAGTTGCGGGGAGAATGATTTGAGATTTTTACCTCCTTTGATTT
TGCAAAAAGAACATATTGATGAAATGAGTGAAAAGTTAAGAAAGGCTCTAAAGAGTTTTTGA

Upstream 100 bases:

>100_bases
CAAAAAGGTACATATTTTAGATGGGCGTGTGAAACATTCTTTGTTGCTTGAGTTTTTTACCGATGAAGGTATAGGCACTT
TGGTGGGTTAAAGGATGAAA

Downstream 100 bases:

>100_bases
TAAATTTTGTAAAAAAAGTTTATTCTTTCCCATCTACTATAGGCACAAATAAACATTCTTCTAAAATTTCTTTTTGTAAA
TTTGTGCCATTTTTTCTAAG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MDYKEQSHIVPTYKRFDIVLEKGQGVYLFDDKAKKYLDFSSGIGVCALGYNHAKFNAKIKAQVDKLLHTSNLYYNENIAA
AAKNLAKASALERVFFTNSGTESIEGAMKTARKYAFNKGIKGGQFIAFKHSFHGRTLGALSLTANEKYQKPFKPLISGVK
FAKYNDILSVEKLVNEKTCAIILESVQGEGGINPANKDFYKALRKLCDEKDILLIADEIQCGMGRSGKFFAYEHAQILPD
IMTSAKALGCGLSVGAFVINQKVASNSLEAGDHGSTYGGNPLVCAGVNAVFEIFKEEKILENVNKLTPYLEQSLDELINE
FDFCKKRKGLGFMQGLSLDKNVKVAKVIQKCQENALLLISCGENDLRFLPPLILQKEHIDEMSEKLRKALKSF

Sequences:

>Translated_393_residues
MDYKEQSHIVPTYKRFDIVLEKGQGVYLFDDKAKKYLDFSSGIGVCALGYNHAKFNAKIKAQVDKLLHTSNLYYNENIAA
AAKNLAKASALERVFFTNSGTESIEGAMKTARKYAFNKGIKGGQFIAFKHSFHGRTLGALSLTANEKYQKPFKPLISGVK
FAKYNDILSVEKLVNEKTCAIILESVQGEGGINPANKDFYKALRKLCDEKDILLIADEIQCGMGRSGKFFAYEHAQILPD
IMTSAKALGCGLSVGAFVINQKVASNSLEAGDHGSTYGGNPLVCAGVNAVFEIFKEEKILENVNKLTPYLEQSLDELINE
FDFCKKRKGLGFMQGLSLDKNVKVAKVIQKCQENALLLISCGENDLRFLPPLILQKEHIDEMSEKLRKALKSF
>Mature_393_residues
MDYKEQSHIVPTYKRFDIVLEKGQGVYLFDDKAKKYLDFSSGIGVCALGYNHAKFNAKIKAQVDKLLHTSNLYYNENIAA
AAKNLAKASALERVFFTNSGTESIEGAMKTARKYAFNKGIKGGQFIAFKHSFHGRTLGALSLTANEKYQKPFKPLISGVK
FAKYNDILSVEKLVNEKTCAIILESVQGEGGINPANKDFYKALRKLCDEKDILLIADEIQCGMGRSGKFFAYEHAQILPD
IMTSAKALGCGLSVGAFVINQKVASNSLEAGDHGSTYGGNPLVCAGVNAVFEIFKEEKILENVNKLTPYLEQSLDELINE
FDFCKKRKGLGFMQGLSLDKNVKVAKVIQKCQENALLLISCGENDLRFLPPLILQKEHIDEMSEKLRKALKSF

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=398, Percent_Identity=32.4120603015075, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI284507298, Length=302, Percent_Identity=32.4503311258278, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI13994255, Length=442, Percent_Identity=27.8280542986425, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI226442705, Length=430, Percent_Identity=27.4418604651163, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI37574042, Length=430, Percent_Identity=27.4418604651163, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI24119277, Length=408, Percent_Identity=24.7549019607843, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI226442709, Length=367, Percent_Identity=27.5204359673025, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI188536080, Length=413, Percent_Identity=24.6973365617433, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI38679950, Length=413, Percent_Identity=24.6973365617433, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI38679946, Length=413, Percent_Identity=24.6973365617433, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1788044, Length=388, Percent_Identity=36.340206185567, Blast_Score=281, Evalue=6e-77,
Organism=Escherichia coli, GI1789759, Length=385, Percent_Identity=36.6233766233766, Blast_Score=280, Evalue=9e-77,
Organism=Escherichia coli, GI145693181, Length=380, Percent_Identity=33.4210526315789, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1787560, Length=400, Percent_Identity=32.75, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1789016, Length=394, Percent_Identity=30.9644670050761, Blast_Score=175, Evalue=6e-45,
Organism=Escherichia coli, GI1786991, Length=414, Percent_Identity=28.5024154589372, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786349, Length=324, Percent_Identity=29.9382716049383, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25144271, Length=386, Percent_Identity=32.3834196891192, Blast_Score=219, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI25144274, Length=383, Percent_Identity=28.4595300261097, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI32564660, Length=441, Percent_Identity=28.7981859410431, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=410, Percent_Identity=25.3658536585366, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17541228, Length=440, Percent_Identity=25, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71981843, Length=168, Percent_Identity=27.9761904761905, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=405, Percent_Identity=38.2716049382716, Blast_Score=276, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6323470, Length=399, Percent_Identity=28.3208020050125, Blast_Score=175, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6324386, Length=305, Percent_Identity=28.1967213114754, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=426, Percent_Identity=25.1173708920188, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357415, Length=395, Percent_Identity=31.6455696202532, Blast_Score=217, Evalue=9e-57,
Organism=Drosophila melanogaster, GI161085790, Length=443, Percent_Identity=28.8939051918736, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI28574759, Length=426, Percent_Identity=28.6384976525822, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI21356575, Length=422, Percent_Identity=26.303317535545, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI281366494, Length=426, Percent_Identity=26.5258215962441, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24667139, Length=426, Percent_Identity=26.5258215962441, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24667143, Length=426, Percent_Identity=26.5258215962441, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43573; Mature: 43573

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYKEQSHIVPTYKRFDIVLEKGQGVYLFDDKAKKYLDFSSGIGVCALGYNHAKFNAKIK
CCCCCCCCCCCCHHHEEEEEECCCEEEEECCCHHHHHCCCCCCCEEEECCCCCEECCHHH
AQVDKLLHTSNLYYNENIAAAAKNLAKASALERVFFTNSGTESIEGAMKTARKYAFNKGI
HHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
KGGQFIAFKHSFHGRTLGALSLTANEKYQKPFKPLISGVKFAKYNDILSVEKLVNEKTCA
CCCEEEEEEECCCCCEEEEEEECCCHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCCHHHH
IILESVQGEGGINPANKDFYKALRKLCDEKDILLIADEIQCGMGRSGKFFAYEHAQILPD
HHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEHHHHHHHH
IMTSAKALGCGLSVGAFVINQKVASNSLEAGDHGSTYGGNPLVCAGVNAVFEIFKEEKIL
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHH
ENVNKLTPYLEQSLDELINEFDFCKKRKGLGFMQGLSLDKNVKVAKVIQKCQENALLLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHCCCEEEEE
CGENDLRFLPPLILQKEHIDEMSEKLRKALKSF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDYKEQSHIVPTYKRFDIVLEKGQGVYLFDDKAKKYLDFSSGIGVCALGYNHAKFNAKIK
CCCCCCCCCCCCHHHEEEEEECCCEEEEECCCHHHHHCCCCCCCEEEECCCCCEECCHHH
AQVDKLLHTSNLYYNENIAAAAKNLAKASALERVFFTNSGTESIEGAMKTARKYAFNKGI
HHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
KGGQFIAFKHSFHGRTLGALSLTANEKYQKPFKPLISGVKFAKYNDILSVEKLVNEKTCA
CCCEEEEEEECCCCCEEEEEEECCCHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCCHHHH
IILESVQGEGGINPANKDFYKALRKLCDEKDILLIADEIQCGMGRSGKFFAYEHAQILPD
HHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEHHHHHHHH
IMTSAKALGCGLSVGAFVINQKVASNSLEAGDHGSTYGGNPLVCAGVNAVFEIFKEEKIL
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHH
ENVNKLTPYLEQSLDELINEFDFCKKRKGLGFMQGLSLDKNVKVAKVIQKCQENALLLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHCCCEEEEE
CGENDLRFLPPLILQKEHIDEMSEKLRKALKSF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10588044; 10688204 [H]