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The map label for this gene is mcpB [H]

Identifier: 57237152

GI number: 57237152

Start: 145824

End: 147446

Strand: Direct

Name: mcpB [H]

Synonym: CJE0140

Alternate gene names: 57237152

Gene position: 145824-147446 (Clockwise)

Preceding gene: 57237151

Following gene: 57237153

Centisome position: 8.2

GC content: 31.24

Gene sequence:

>1623_bases
ATGAGTAGTGATCTAAGCGAGAAAAAAAATACTAATATAACTATAAATGGAAAAGCCAACAACTATAATGCAACTACTAG
GGAATGGTATAAAGGAGCTAGAAATAGTAATCAAATCTATATAACCCCAGCTTATATTGATGCTTTTACTAATGAATACT
GTATTACTTACTCTAAAGCTCTTTATAAGGATGGTAAATTTATTGGTGTTTTAGGAATTGATGTTTTATTAACTAGTTTA
CAAGATCAAATTGCTAGAACTCCAGGCAATACCTTTGCTTTTGATAATAAAGATAAAATATTTGCAGCCACCAACGAAGC
TTTATTAGATCCTTCGGTAGACCATTCTCCTGTTCTAAATGCATATAAAGCTCATGGTGATAACAACTTCTTCTCTTATA
AGTTAAATAATGAAGAAAGACTTGGAGCTTGTACTAAAGTCTTTGCTTATACAGCTTGTATTACCGAAAGCGCTGATATT
ATAAATAAACCTATATTTAAAGCAGCATATATACAAGTTATAGCCTTAATTGTTATGATATCTATTAGCATCATCCTCCT
TTATTTCATCGTATCAAAATACCTCTCCCCACTTGCAGCTATCCAAACAGGTTTAACTTCATTCTTTGATTTTATCAACT
ATAAAACAAAAAATGTTTCTACTATAGAAGTAAAAAGCAATGATGAATTTGGACAAATCTCAAATGCTATCAATGAAAAC
ATTCTTGCTACTAAAAGAGGCTTAGAACAAGACAATCAAGCCGTTAAAGAATCAGTTCAAACCGTATCAGTTGTAGAAGG
TGGTAATTTAACAGCAAGAATTACTGCTAATCCAAGAAACCCACAGCTTATTGAACTTAAAAATGTTCTAAATAAACTTC
TTGATGTTTTACAAGCTAGAGTAGGTTCTGATATGAATGCTATTCATAAAATTTTTGAAGAATACAAAAGCTTAGACTTT
AGAAATAAATTAGAAAATGCTAGCGGTAGTGTAGAATTAACTACTAATGCTTTAGGTGATGAAATAGTTAAAATGCTAAA
ACAAAGTTCAGACTTTGCTAATGCCTTAGCTAATGAAAGTGGAAAATTACAAACTGCTGTTCAAAGCTTAACCACTTCTT
CAAATTCTCAAGCTCAATCTTTAGAAGAAACTGCAGCAGCTTTAGAAGAGATCACTTCTTCTATGCAAAATGTTTCAGTT
AAAACTAGTGATGTTATCACTCAATCTGAAGAGATTAAAAATGTTACAGGTATTATAGGTGATATTGCAGATCAAATCAA
TCTTCTAGCTTTAAATGCAGCTATTGAAGCAGCTCGTGCTGGAGAACATGGTAGAGGCTTTGCAGTGGTAGCTGATGAAG
TTAGAAAGTTAGCTGAAAGAACTCAAAAGTCTTTATCAGAAATTGAAGCTAATACTAATTTACTTGTTCAATCTATCAAT
GATATGGCAGAAAGTATTAAAGAACAAACTGCAGGTATCACTCAAATCAATGATAGCGTAGCTCAAATTGATCAAACTAC
TAAAGATAATGTTGAAATTGCTAATGAATCAGCTATTATTTCTAGTACAGTAAGTGATATAGCTAATAATATCTTAGAAG
ATGTTAAGAAGAAGAGGTTTTAA

Upstream 100 bases:

>100_bases
AAGATAACATAGTTAATAATGTAGGGGTCATATTAAAATACTACCGCAATAGTGGAATTTGCTTGCTGTTTATATTGGTT
TAGATAATGGTGAAAATATC

Downstream 100 bases:

>100_bases
TTAATCATTTATACCTAGTAAAAAACTAGGTATAAATTTTTCCTTCAATTTAAATTTTTCATCAAAGTTTCTAAAAAGTT
TCCAAATATTTTTATACTTC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 540; Mature: 539

Protein sequence:

>540_residues
MSSDLSEKKNTNITINGKANNYNATTREWYKGARNSNQIYITPAYIDAFTNEYCITYSKALYKDGKFIGVLGIDVLLTSL
QDQIARTPGNTFAFDNKDKIFAATNEALLDPSVDHSPVLNAYKAHGDNNFFSYKLNNEERLGACTKVFAYTACITESADI
INKPIFKAAYIQVIALIVMISISIILLYFIVSKYLSPLAAIQTGLTSFFDFINYKTKNVSTIEVKSNDEFGQISNAINEN
ILATKRGLEQDNQAVKESVQTVSVVEGGNLTARITANPRNPQLIELKNVLNKLLDVLQARVGSDMNAIHKIFEEYKSLDF
RNKLENASGSVELTTNALGDEIVKMLKQSSDFANALANESGKLQTAVQSLTTSSNSQAQSLEETAAALEEITSSMQNVSV
KTSDVITQSEEIKNVTGIIGDIADQINLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANTNLLVQSIN
DMAESIKEQTAGITQINDSVAQIDQTTKDNVEIANESAIISSTVSDIANNILEDVKKKRF

Sequences:

>Translated_540_residues
MSSDLSEKKNTNITINGKANNYNATTREWYKGARNSNQIYITPAYIDAFTNEYCITYSKALYKDGKFIGVLGIDVLLTSL
QDQIARTPGNTFAFDNKDKIFAATNEALLDPSVDHSPVLNAYKAHGDNNFFSYKLNNEERLGACTKVFAYTACITESADI
INKPIFKAAYIQVIALIVMISISIILLYFIVSKYLSPLAAIQTGLTSFFDFINYKTKNVSTIEVKSNDEFGQISNAINEN
ILATKRGLEQDNQAVKESVQTVSVVEGGNLTARITANPRNPQLIELKNVLNKLLDVLQARVGSDMNAIHKIFEEYKSLDF
RNKLENASGSVELTTNALGDEIVKMLKQSSDFANALANESGKLQTAVQSLTTSSNSQAQSLEETAAALEEITSSMQNVSV
KTSDVITQSEEIKNVTGIIGDIADQINLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANTNLLVQSIN
DMAESIKEQTAGITQINDSVAQIDQTTKDNVEIANESAIISSTVSDIANNILEDVKKKRF
>Mature_539_residues
SSDLSEKKNTNITINGKANNYNATTREWYKGARNSNQIYITPAYIDAFTNEYCITYSKALYKDGKFIGVLGIDVLLTSLQ
DQIARTPGNTFAFDNKDKIFAATNEALLDPSVDHSPVLNAYKAHGDNNFFSYKLNNEERLGACTKVFAYTACITESADII
NKPIFKAAYIQVIALIVMISISIILLYFIVSKYLSPLAAIQTGLTSFFDFINYKTKNVSTIEVKSNDEFGQISNAINENI
LATKRGLEQDNQAVKESVQTVSVVEGGNLTARITANPRNPQLIELKNVLNKLLDVLQARVGSDMNAIHKIFEEYKSLDFR
NKLENASGSVELTTNALGDEIVKMLKQSSDFANALANESGKLQTAVQSLTTSSNSQAQSLEETAAALEEITSSMQNVSVK
TSDVITQSEEIKNVTGIIGDIADQINLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANTNLLVQSIND
MAESIKEQTAGITQINDSVAQIDQTTKDNVEIANESAIISSTVSDIANNILEDVKKKRF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=277, Percent_Identity=28.5198555956679, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1787690, Length=222, Percent_Identity=31.5315315315315, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788194, Length=218, Percent_Identity=33.0275229357798, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1788195, Length=253, Percent_Identity=30.4347826086957, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789453, Length=210, Percent_Identity=31.4285714285714, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 59085; Mature: 58954

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDLSEKKNTNITINGKANNYNATTREWYKGARNSNQIYITPAYIDAFTNEYCITYSKA
CCCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCCCEEEEEEHHHHHHCCCHHEEHHHH
LYKDGKFIGVLGIDVLLTSLQDQIARTPGNTFAFDNKDKIFAATNEALLDPSVDHSPVLN
HHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEECCCHHCCCCCCCCHHHH
AYKAHGDNNFFSYKLNNEERLGACTKVFAYTACITESADIINKPIFKAAYIQVIALIVMI
HHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHH
SISIILLYFIVSKYLSPLAAIQTGLTSFFDFINYKTKNVSTIEVKSNDEFGQISNAINEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHH
ILATKRGLEQDNQAVKESVQTVSVVEGGNLTARITANPRNPQLIELKNVLNKLLDVLQAR
HHHHHHCCCHHHHHHHHHHHHEEEEECCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHH
VGSDMNAIHKIFEEYKSLDFRNKLENASGSVELTTNALGDEIVKMLKQSSDFANALANES
HCCCHHHHHHHHHHHHCCCHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHCCC
GKLQTAVQSLTTSSNSQAQSLEETAAALEEITSSMQNVSVKTSDVITQSEEIKNVTGIIG
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
DIADQINLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANTNLLVQSIN
HHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
DMAESIKEQTAGITQINDSVAQIDQTTKDNVEIANESAIISSTVSDIANNILEDVKKKRF
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSDLSEKKNTNITINGKANNYNATTREWYKGARNSNQIYITPAYIDAFTNEYCITYSKA
CCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCCCEEEEEEHHHHHHCCCHHEEHHHH
LYKDGKFIGVLGIDVLLTSLQDQIARTPGNTFAFDNKDKIFAATNEALLDPSVDHSPVLN
HHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEECCCHHCCCCCCCCHHHH
AYKAHGDNNFFSYKLNNEERLGACTKVFAYTACITESADIINKPIFKAAYIQVIALIVMI
HHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHH
SISIILLYFIVSKYLSPLAAIQTGLTSFFDFINYKTKNVSTIEVKSNDEFGQISNAINEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHH
ILATKRGLEQDNQAVKESVQTVSVVEGGNLTARITANPRNPQLIELKNVLNKLLDVLQAR
HHHHHHCCCHHHHHHHHHHHHEEEEECCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHH
VGSDMNAIHKIFEEYKSLDFRNKLENASGSVELTTNALGDEIVKMLKQSSDFANALANES
HCCCHHHHHHHHHHHHCCCHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHCCC
GKLQTAVQSLTTSSNSQAQSLEETAAALEEITSSMQNVSVKTSDVITQSEEIKNVTGIIG
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
DIADQINLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANTNLLVQSIN
HHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
DMAESIKEQTAGITQINDSVAQIDQTTKDNVEIANESAIISSTVSDIANNILEDVKKKRF
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]