Click here to switch to the map view.

The map label for this gene is accD [H]

Identifier: 57237134

GI number: 57237134

Start: 127234

End: 128076

Strand: Reverse

Name: accD [H]

Synonym: CJE0122

Alternate gene names: 57237134

Gene position: 128076-127234 (Counterclockwise)

Preceding gene: 57237135

Following gene: 57237133

Centisome position: 7.2

GC content: 33.81

Gene sequence:

>843_bases
ATGAATTTTGCAGATATTTTTTCAAAAATAAGAAGACAACAACCTAGCGTTAAAGAAGCGCCAAATCACTGGGTAAAGTG
CCAAAGTTGTCATGCTTTGATGTATTATAAAGAAATAGAATCTTGTTTTAATGTTTGTCCTAAATGCAATTATCACATGA
GAATTTCAGCTGATGAACGTATTAAACTTTTAAGCGATGAAGGCAGTTTTATTGAGTATGATGCAAATTTAGAAGCTATA
GATCCTTTAAAATTTGTTGATAGCAAATCCTATAAAAAACGCCTTAGCGAAGGTGAAAGTAAAACAGGTAGAAAAAGTTC
TGTCATCAGTGGAGAATGTGAAATCAATGGTTTAAAAACCCAACTTGTTGTATTTGATTTTTCTTTTATGGGCGGATCTT
TAGGTTCTGTTGAAGGAGAAAAAATTGTTAGAGCTATACAAAGAGCTATCACAAGCAAAACTTCTCTTGTCATCGTAAGT
GCAAGCGGTGGAGCTAGAATGCAAGAAAGTACTTATTCTTTGATGCAAATGAGCAAAACTAGTGCTGCACTTAAACTTCT
TAGCAAAGAAAAACTTCCTTATATTAGCATTTTAACCGATCCTACTATGGGTGGAGTAAGTGCTTCTTTTGCTTGGCTTG
GAGATTTAATCATCGCTGAACCTGAAGCTTTAGTAGGTTTTGCTGGTGCAAGAGTTATTAAACAAACTATAGGAGCAGAT
TTACCTGAAGGTTTTCAAAAAGCAGAGTTCTTGTTAGAACATGGACTTATAGATGCCATAGTTGAAAGAGGAGAACAAAA
ACAATATCTTAGCGATGTACTAAAATTTTTTAGTGGAAAATAA

Upstream 100 bases:

>100_bases
ATTTATATATAGAAAAAAATGAAAATTTCCTTCTCCTAAGCCAAGACAAAAAAATTTTTGATATAATCTTAGAATTTTTA
AAAAATAATTAGGTGAATAT

Downstream 100 bases:

>100_bases
TTTGCAAGTTAATATCTTTTGTATTCAAAAAAGTGATGAATTTAAAACTTGGAGTGAGAAATACTCTAAACTCATCTCCA
AATACGCCACTTTAAAAGAA

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MNFADIFSKIRRQQPSVKEAPNHWVKCQSCHALMYYKEIESCFNVCPKCNYHMRISADERIKLLSDEGSFIEYDANLEAI
DPLKFVDSKSYKKRLSEGESKTGRKSSVISGECEINGLKTQLVVFDFSFMGGSLGSVEGEKIVRAIQRAITSKTSLVIVS
ASGGARMQESTYSLMQMSKTSAALKLLSKEKLPYISILTDPTMGGVSASFAWLGDLIIAEPEALVGFAGARVIKQTIGAD
LPEGFQKAEFLLEHGLIDAIVERGEQKQYLSDVLKFFSGK

Sequences:

>Translated_280_residues
MNFADIFSKIRRQQPSVKEAPNHWVKCQSCHALMYYKEIESCFNVCPKCNYHMRISADERIKLLSDEGSFIEYDANLEAI
DPLKFVDSKSYKKRLSEGESKTGRKSSVISGECEINGLKTQLVVFDFSFMGGSLGSVEGEKIVRAIQRAITSKTSLVIVS
ASGGARMQESTYSLMQMSKTSAALKLLSKEKLPYISILTDPTMGGVSASFAWLGDLIIAEPEALVGFAGARVIKQTIGAD
LPEGFQKAEFLLEHGLIDAIVERGEQKQYLSDVLKFFSGK
>Mature_280_residues
MNFADIFSKIRRQQPSVKEAPNHWVKCQSCHALMYYKEIESCFNVCPKCNYHMRISADERIKLLSDEGSFIEYDANLEAI
DPLKFVDSKSYKKRLSEGESKTGRKSSVISGECEINGLKTQLVVFDFSFMGGSLGSVEGEKIVRAIQRAITSKTSLVIVS
ASGGARMQESTYSLMQMSKTSAALKLLSKEKLPYISILTDPTMGGVSASFAWLGDLIIAEPEALVGFAGARVIKQTIGAD
LPEGFQKAEFLLEHGLIDAIVERGEQKQYLSDVLKFFSGK

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=190, Percent_Identity=27.8947368421053, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788655, Length=251, Percent_Identity=53.3864541832669, Blast_Score=281, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI25147359, Length=181, Percent_Identity=28.7292817679558, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI25147362, Length=181, Percent_Identity=28.7292817679558, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 30952; Mature: 30952

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFADIFSKIRRQQPSVKEAPNHWVKCQSCHALMYYKEIESCFNVCPKCNYHMRISADER
CCHHHHHHHHHHCCCCHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
IKLLSDEGSFIEYDANLEAIDPLKFVDSKSYKKRLSEGESKTGRKSSVISGECEINGLKT
EEEECCCCCEEEECCCCCCCCCHHHHCCHHHHHHHHCCCCCCCCCCCEEECCEEECCCEE
QLVVFDFSFMGGSLGSVEGEKIVRAIQRAITSKTSLVIVSASGGARMQESTYSLMQMSKT
EEEEEEEHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
SAALKLLSKEKLPYISILTDPTMGGVSASFAWLGDLIIAEPEALVGFAGARVIKQTIGAD
HHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
LPEGFQKAEFLLEHGLIDAIVERGEQKQYLSDVLKFFSGK
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNFADIFSKIRRQQPSVKEAPNHWVKCQSCHALMYYKEIESCFNVCPKCNYHMRISADER
CCHHHHHHHHHHCCCCHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
IKLLSDEGSFIEYDANLEAIDPLKFVDSKSYKKRLSEGESKTGRKSSVISGECEINGLKT
EEEECCCCCEEEECCCCCCCCCHHHHCCHHHHHHHHCCCCCCCCCCCEEECCEEECCCEE
QLVVFDFSFMGGSLGSVEGEKIVRAIQRAITSKTSLVIVSASGGARMQESTYSLMQMSKT
EEEEEEEHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
SAALKLLSKEKLPYISILTDPTMGGVSASFAWLGDLIIAEPEALVGFAGARVIKQTIGAD
HHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
LPEGFQKAEFLLEHGLIDAIVERGEQKQYLSDVLKFFSGK
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500908 [H]