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The map label for this gene is mtnA [H]

Identifier: 57237124

GI number: 57237124

Start: 120687

End: 121376

Strand: Direct

Name: mtnA [H]

Synonym: CJE0112

Alternate gene names: 57237124

Gene position: 120687-121376 (Clockwise)

Preceding gene: 57237123

Following gene: 57237125

Centisome position: 6.79

GC content: 33.91

Gene sequence:

>690_bases
ATGATGAAAATAGCAATTTTAGGAGCCATGAGTGAAGAAATCACTCCTTTACTTGAAACACTTAAAGATTATACGAAAAT
AGAACACGCTAACAATACTTATTATTTTGCAAAGTATAAAAACCATGAACTTGTTTTAGCGTATTCTAAAATTGGCAAGG
TAAATTCTACTCTTAGTGCTAGTGTGATGATAGAAAAATTTGGCGCACAAGCTTTGCTTTTTACAGGAGTTGCAGGTGCT
TTTAATCCTGAACTTGAAATTGGCGATTTGCTTTATGCAACAAAATTAGCTCAATACGATCTTGATATTACTGCTTTTGG
ACATCCTTTGGGTTTTGTTCCAGGTAATGAAATTTTTATCAAAACCGATGAGAAATTAAACAATCTTGCTTTAGAAGTTG
CTAAGGAATTAAATATCAAACTGCGTGCAGGTATTATTGCAACGGGTGATGAGTTTATTTGCGATGAAGCAAAAAAAGCA
AAAATTAGAGAAATTTTCAATGCGGATGCTTGTGAAATGGAAGGCGCAAGTGTGGCTTTGGTTTGTGATGCTTTAAAGGT
GCCTTGTTTTATCTTAAGAGCTATGAGTGATAAAGCAGGGGAAAAGGCTGAATTTGATTTTGATGAGTTTGTGATCAATT
CAGCTAAAATTTCAGCCAATTTTGTGCTTAAAATGTGCGAGAAATTATGA

Upstream 100 bases:

>100_bases
TTGGCGCAAGTGTGCTTAAGGGTTTGAATAAAAAAATCACTTCAAAAGAAACTTATGCTTTAACAAATATGAATGATATT
GATGAATTTTTAAAGGTTGT

Downstream 100 bases:

>100_bases
TAAATCTTAGCAAAAAACTCATACGCCAAGTTGCACAAGCTAATGCTAAATTTGGACTTATTAAAGATGGAGATAGGGTT
CTTTTAGGGCTTAGTGGCGG

Product: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: 5'-methylthioadenosine nucleosidase; S-adenosylhomocysteine nucleosidase [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MMKIAILGAMSEEITPLLETLKDYTKIEHANNTYYFAKYKNHELVLAYSKIGKVNSTLSASVMIEKFGAQALLFTGVAGA
FNPELEIGDLLYATKLAQYDLDITAFGHPLGFVPGNEIFIKTDEKLNNLALEVAKELNIKLRAGIIATGDEFICDEAKKA
KIREIFNADACEMEGASVALVCDALKVPCFILRAMSDKAGEKAEFDFDEFVINSAKISANFVLKMCEKL

Sequences:

>Translated_229_residues
MMKIAILGAMSEEITPLLETLKDYTKIEHANNTYYFAKYKNHELVLAYSKIGKVNSTLSASVMIEKFGAQALLFTGVAGA
FNPELEIGDLLYATKLAQYDLDITAFGHPLGFVPGNEIFIKTDEKLNNLALEVAKELNIKLRAGIIATGDEFICDEAKKA
KIREIFNADACEMEGASVALVCDALKVPCFILRAMSDKAGEKAEFDFDEFVINSAKISANFVLKMCEKL
>Mature_229_residues
MMKIAILGAMSEEITPLLETLKDYTKIEHANNTYYFAKYKNHELVLAYSKIGKVNSTLSASVMIEKFGAQALLFTGVAGA
FNPELEIGDLLYATKLAQYDLDITAFGHPLGFVPGNEIFIKTDEKLNNLALEVAKELNIKLRAGIIATGDEFICDEAKKA
KIREIFNADACEMEGASVALVCDALKVPCFILRAMSDKAGEKAEFDFDEFVINSAKISANFVLKMCEKL

Specific function: Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=229, Percent_Identity=36.6812227074236, Blast_Score=129, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 25226; Mature: 25226

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKIAILGAMSEEITPLLETLKDYTKIEHANNTYYFAKYKNHELVLAYSKIGKVNSTLSA
CEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEECCCCCCCCHHH
SVMIEKFGAQALLFTGVAGAFNPELEIGDLLYATKLAQYDLDITAFGHPLGFVPGNEIFI
HHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEE
KTDEKLNNLALEVAKELNIKLRAGIIATGDEFICDEAKKAKIREIFNADACEMEGASVAL
ECCCHHHHHHHHHHHHCCEEEEEEEEECCCHHHHCCHHHHHHHHHHCCCCCCCCCCEEEE
VCDALKVPCFILRAMSDKAGEKAEFDFDEFVINSAKISANFVLKMCEKL
EEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMKIAILGAMSEEITPLLETLKDYTKIEHANNTYYFAKYKNHELVLAYSKIGKVNSTLSA
CEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEECCCCCCCCHHH
SVMIEKFGAQALLFTGVAGAFNPELEIGDLLYATKLAQYDLDITAFGHPLGFVPGNEIFI
HHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEE
KTDEKLNNLALEVAKELNIKLRAGIIATGDEFICDEAKKAKIREIFNADACEMEGASVAL
ECCCHHHHHHHHHHHHCCEEEEEEEEECCCHHHHCCHHHHHHHHHHCCCCCCCCCCEEEE
VCDALKVPCFILRAMSDKAGEKAEFDFDEFVINSAKISANFVLKMCEKL
EEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]