Click here to switch to the map view.

The map label for this gene is atpA

Identifier: 57237112

GI number: 57237112

Start: 110495

End: 112000

Strand: Direct

Name: atpA

Synonym: CJE0100

Alternate gene names: 57237112

Gene position: 110495-112000 (Clockwise)

Preceding gene: 57237111

Following gene: 57237113

Centisome position: 6.22

GC content: 35.33

Gene sequence:

>1506_bases
ATGAAATTTAAAGCTGATGAGATCAGTTCAATAATCAAAGAAAGAATTGAAAATTTTGATTTAAATCTTGAAATTGAAGA
AACAGGAAAGATTATTTCTGTAGCTGATGGTGTTGCTAAGGTATATGGACTTAAGAATATTATGGCTGGAGAAATGGTAG
AATTTGAAAATGGTGATAAAGGAATGGCCTTAAACCTTGAAGAGTCGAGTGTAGGTATTGTTATACTTGGAAAAGGAGAA
GGTTTAAAAGAAGGTGCTTCTGTAAAAAGACTTAAGAAATTACTTAAAGTTCCAGTAGGTGAGGCTTTGATTGGCCGTGT
TGTAAATGCTTTAGGTGAGCCAATTGATGCTAAAGGTGTGATCAATGCTAATGAATATCGTTTTGTTGAAGAAAAAGCAA
AAGGTATTATGGCGAGAAAAAGTGTTCATGAGCCTTTACATACAGGAATTAAAGCTATTGATGCGCTTGTGCCAATTGGT
CGTGGTCAAAGAGAGCTTATCATAGGTGATAGACAAACAGGTAAAACTACTGTTGCTGTTGATACTATTATATCTCAAAG
AGGTCAAGGAGTTATCTGTATATATGTTGCAATTGGTCAAAAGCAAAGTACAGTGGCACAAGTGGTTAAAAGACTAGAAG
AACATGGTGCTATGGAATATACTATTGTTGTAAATGCCGGTGCTTCAGATCCTGCGGCTTTACAGTACTTAGCTCCATAT
ACTGGTGTAACCATGGGTGAATTTTTTAGAGACAACGCAAAACATGCTTTAATTGTTTATGATGATTTGAGCAAGCATGC
TGTAGCTTATCGCGAAATGTCTTTGATTTTACGTCGTCCTCCAGGTCGTGAAGCTTATCCAGGCGATGTTTTTTACCTTC
ATTCAAGATTGCTTGAAAGAGCAAGCAAGCTAAATGATGAATTAGGTGCTGGTTCTTTGACGGCATTGCCGATAATTGAA
ACACAAGCAGGAGATGTTTCTGCTTATATTCCAACTAATGTTATTTCAATTACAGATGGACAAATTTTCTTAGAAACTGA
TTTATTTAACTCAGGAATTCGTCCTGCAATTAATGTTGGTTTATCAGTATCTCGTGTAGGTGGGGCTGCTCAAATTAAAG
CTACAAAACAAGTTTCAGGCACATTAAGACTTGACCTTGCTCAATATAGAGAGCTTCAAGCTTTTGCACAATTTGCTAGT
GATTTAGATGAGGCAAGTAGAAAACAACTTGAACGTGGACAAAGAATGGTTGAACTCTTAAAACAACCACCTTATTCTCC
GCTTAGCGTTGAAAAACAAGTAGTTTTAATTTTTGCAGGAACCAAAGGTTTCTTAGATGATATTGCTGTTTCTAGAATTA
AGGAATTTGAAGATGGAATTTATCCTTTTATTGAGGCAAAACATCCAGATATTTTTGAGCAAATTCGCTCTAAAAAAGCT
TTAGATTCTGATTTGGAAGAAAAACTAGCTAAAGCCATTAATGAGTTTAAAGCAAATCATTTATAA

Upstream 100 bases:

>100_bases
GAATTAGAAGAATTAGGTTATGAACTTTCTTTTTCTATGAAAGCTCTTCAAAATAAGCTAAACGAATATATATTGAAAAT
TATCTAAGGAGAAAAAGTAA

Downstream 100 bases:

>100_bases
GGTCTTTTATGTCTAATTTAAAAGAAATTAAAAGAAAAATTAAAAGTGTTCATAACACTCAAAAGACTACAAATGCTATG
AAGCTAGTTTCTACTGCTAA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MKFKADEISSIIKERIENFDLNLEIEETGKIISVADGVAKVYGLKNIMAGEMVEFENGDKGMALNLEESSVGIVILGKGE
GLKEGASVKRLKKLLKVPVGEALIGRVVNALGEPIDAKGVINANEYRFVEEKAKGIMARKSVHEPLHTGIKAIDALVPIG
RGQRELIIGDRQTGKTTVAVDTIISQRGQGVICIYVAIGQKQSTVAQVVKRLEEHGAMEYTIVVNAGASDPAALQYLAPY
TGVTMGEFFRDNAKHALIVYDDLSKHAVAYREMSLILRRPPGREAYPGDVFYLHSRLLERASKLNDELGAGSLTALPIIE
TQAGDVSAYIPTNVISITDGQIFLETDLFNSGIRPAINVGLSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFAQFAS
DLDEASRKQLERGQRMVELLKQPPYSPLSVEKQVVLIFAGTKGFLDDIAVSRIKEFEDGIYPFIEAKHPDIFEQIRSKKA
LDSDLEEKLAKAINEFKANHL

Sequences:

>Translated_501_residues
MKFKADEISSIIKERIENFDLNLEIEETGKIISVADGVAKVYGLKNIMAGEMVEFENGDKGMALNLEESSVGIVILGKGE
GLKEGASVKRLKKLLKVPVGEALIGRVVNALGEPIDAKGVINANEYRFVEEKAKGIMARKSVHEPLHTGIKAIDALVPIG
RGQRELIIGDRQTGKTTVAVDTIISQRGQGVICIYVAIGQKQSTVAQVVKRLEEHGAMEYTIVVNAGASDPAALQYLAPY
TGVTMGEFFRDNAKHALIVYDDLSKHAVAYREMSLILRRPPGREAYPGDVFYLHSRLLERASKLNDELGAGSLTALPIIE
TQAGDVSAYIPTNVISITDGQIFLETDLFNSGIRPAINVGLSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFAQFAS
DLDEASRKQLERGQRMVELLKQPPYSPLSVEKQVVLIFAGTKGFLDDIAVSRIKEFEDGIYPFIEAKHPDIFEQIRSKKA
LDSDLEEKLAKAINEFKANHL
>Mature_501_residues
MKFKADEISSIIKERIENFDLNLEIEETGKIISVADGVAKVYGLKNIMAGEMVEFENGDKGMALNLEESSVGIVILGKGE
GLKEGASVKRLKKLLKVPVGEALIGRVVNALGEPIDAKGVINANEYRFVEEKAKGIMARKSVHEPLHTGIKAIDALVPIG
RGQRELIIGDRQTGKTTVAVDTIISQRGQGVICIYVAIGQKQSTVAQVVKRLEEHGAMEYTIVVNAGASDPAALQYLAPY
TGVTMGEFFRDNAKHALIVYDDLSKHAVAYREMSLILRRPPGREAYPGDVFYLHSRLLERASKLNDELGAGSLTALPIIE
TQAGDVSAYIPTNVISITDGQIFLETDLFNSGIRPAINVGLSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFAQFAS
DLDEASRKQLERGQRMVELLKQPPYSPLSVEKQVVLIFAGTKGFLDDIAVSRIKEFEDGIYPFIEAKHPDIFEQIRSKKA
LDSDLEEKLAKAINEFKANHL

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=500, Percent_Identity=62, Blast_Score=634, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=500, Percent_Identity=62, Blast_Score=634, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=406, Percent_Identity=29.064039408867, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI19913426, Length=291, Percent_Identity=29.2096219931272, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI32189394, Length=443, Percent_Identity=24.8306997742664, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI19913424, Length=251, Percent_Identity=27.0916334661355, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1790172, Length=511, Percent_Identity=56.3600782778865, Blast_Score=594, Evalue=1e-171,
Organism=Escherichia coli, GI1790170, Length=441, Percent_Identity=25.1700680272109, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1788251, Length=322, Percent_Identity=27.639751552795, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=502, Percent_Identity=60.9561752988048, Blast_Score=618, Evalue=1e-177,
Organism=Caenorhabditis elegans, GI71988080, Length=502, Percent_Identity=60.9561752988048, Blast_Score=617, Evalue=1e-177,
Organism=Caenorhabditis elegans, GI71988074, Length=502, Percent_Identity=57.7689243027888, Blast_Score=571, Evalue=1e-163,
Organism=Caenorhabditis elegans, GI17570191, Length=289, Percent_Identity=30.4498269896194, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17510931, Length=289, Percent_Identity=28.719723183391, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=397, Percent_Identity=23.6775818639798, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71988068, Length=71, Percent_Identity=54.9295774647887, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17565854, Length=247, Percent_Identity=27.5303643724696, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=66, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=506, Percent_Identity=60.6719367588933, Blast_Score=624, Evalue=1e-179,
Organism=Saccharomyces cerevisiae, GI6319603, Length=290, Percent_Identity=30.6896551724138, Blast_Score=126, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6322581, Length=424, Percent_Identity=24.7641509433962, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24658560, Length=506, Percent_Identity=59.8814229249012, Blast_Score=610, Evalue=1e-175,
Organism=Drosophila melanogaster, GI281361666, Length=291, Percent_Identity=29.8969072164948, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24646341, Length=291, Percent_Identity=29.8969072164948, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17136796, Length=291, Percent_Identity=29.8969072164948, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28574560, Length=445, Percent_Identity=26.2921348314607, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24638766, Length=395, Percent_Identity=24.3037974683544, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24583992, Length=251, Percent_Identity=26.6932270916335, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI20129479, Length=241, Percent_Identity=29.8755186721992, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583988, Length=251, Percent_Identity=26.6932270916335, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583986, Length=251, Percent_Identity=26.6932270916335, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583984, Length=251, Percent_Identity=26.6932270916335, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_CAMJ8 (A8FJR0)

Other databases:

- EMBL:   CP000814
- RefSeq:   YP_001481674.1
- ProteinModelPortal:   A8FJR0
- SMR:   A8FJR0
- STRING:   A8FJR0
- GeneID:   5617542
- GenomeReviews:   CP000814_GR
- KEGG:   cju:C8J_0098
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   GSDRDIK
- ProtClustDB:   PRK09281
- BioCyc:   CJEJ407148:C8J_0098-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 54802; Mature: 54802

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKADEISSIIKERIENFDLNLEIEETGKIISVADGVAKVYGLKNIMAGEMVEFENGDK
CCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHCCEEEECCCCC
GMALNLEESSVGIVILGKGEGLKEGASVKRLKKLLKVPVGEALIGRVVNALGEPIDAKGV
CEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCC
INANEYRFVEEKAKGIMARKSVHEPLHTGIKAIDALVPIGRGQRELIIGDRQTGKTTVAV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEH
DTIISQRGQGVICIYVAIGQKQSTVAQVVKRLEEHGAMEYTIVVNAGASDPAALQYLAPY
HHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHCCC
TGVTMGEFFRDNAKHALIVYDDLSKHAVAYREMSLILRRPPGREAYPGDVFYLHSRLLER
CCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ASKLNDELGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFNSGIRPAINVG
HHHHCHHCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECCCCCCCCHHHHCC
LSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFAQFASDLDEASRKQLERGQRMVELL
EEEECCCCCEEEEEHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQPPYSPLSVEKQVVLIFAGTKGFLDDIAVSRIKEFEDGIYPFIEAKHPDIFEQIRSKKA
HCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHH
LDSDLEEKLAKAINEFKANHL
HCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKFKADEISSIIKERIENFDLNLEIEETGKIISVADGVAKVYGLKNIMAGEMVEFENGDK
CCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHCCEEEECCCCC
GMALNLEESSVGIVILGKGEGLKEGASVKRLKKLLKVPVGEALIGRVVNALGEPIDAKGV
CEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCC
INANEYRFVEEKAKGIMARKSVHEPLHTGIKAIDALVPIGRGQRELIIGDRQTGKTTVAV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEH
DTIISQRGQGVICIYVAIGQKQSTVAQVVKRLEEHGAMEYTIVVNAGASDPAALQYLAPY
HHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHCCC
TGVTMGEFFRDNAKHALIVYDDLSKHAVAYREMSLILRRPPGREAYPGDVFYLHSRLLER
CCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ASKLNDELGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFNSGIRPAINVG
HHHHCHHCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECCCCCCCCHHHHCC
LSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFAQFASDLDEASRKQLERGQRMVELL
EEEECCCCCEEEEEHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQPPYSPLSVEKQVVLIFAGTKGFLDDIAVSRIKEFEDGIYPFIEAKHPDIFEQIRSKKA
HCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHH
LDSDLEEKLAKAINEFKANHL
HCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA