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The map label for this gene is corA [H]

Identifier: 57237028

GI number: 57237028

Start: 759109

End: 760092

Strand: Reverse

Name: corA [H]

Synonym: CJE0826

Alternate gene names: 57237028

Gene position: 760092-759109 (Counterclockwise)

Preceding gene: 57237036

Following gene: 57237027

Centisome position: 42.75

GC content: 30.59

Gene sequence:

>984_bases
ATGCTTTATATTTATATCAAAACTCAAAATGCTTTAGTTCAAAGAATCAATTTTAATCTCGATAGTCAAGAACTACCACA
AAATATTTTATGGATTGATTTACTTCATCCAAGTGCAGCAGAAATTGCTTTTATATCAAGTGAATTTAATCTTGAGTTTC
CTACAAAAGAAGAAAGGGAAGAAATAGAGCTTAGCGCAAAATATTGGGAAGATAATGCGACAATAACCATCAATGCTCAT
TTTTTAGTAAGAGATCTTAAAAATGATGAAGAGGATAGGAATTTAATCAAGCTTCGCACAGAAATTGTTACTTTTGCTAC
CGCTAAAAATATCTTATTTACTATAAGATATAACGAATTTAGCACTTTTGAAGAAATTCAAGCAAGGATTTTAGCTAGTC
CAAAGAATTTTGAAGATGGTTTTGATATTATTGATAAAATGTTTGAAGTGCGCGTTGAAAAAGATGCGGATTTACTAGAA
TGGATAGATAAAGAAGCAAGACGCTTAAGAACAAGTGTTTTAGAAAAAAAAGATGAATATAGTTATGATGAAATGCTAAA
GGATATTTCAAGTTTGCAAGAGCTTAATATGCGCGTAAGAGATTCTTTATTTGATAAGCGTCGCGCTATGACTTCTTTGC
TAAAAAGCGATAAAATCGATAAAGACATAAAACAAAATCTCACTATAGTTTTAAAAGACTTAAATTCTTTGGTTGAATTT
AGTGTTTCGCAACTTAATATCTTAGATAATATCCAAACCATTTTAGCCAGCCAAATCAACATAGAACAAAACAAAATCAT
TAAAATTTTCACCGTTGCAACTGTTGCCATGATGCCACCTACTTTAATAGGAACTGTTTATGGTATGAATTTTAAATTCA
TGCCCGAACTTGAACTTCACTATGCTTATCCCATAGTGCTTGGCGTGATGGTAATTTCTATCATTTTACCTTTGGTTGTT
TTCAAGAAAAAAGGATGGTTATAA

Upstream 100 bases:

>100_bases
AATATTTTGAAAATTTAATGAGTTTTAGAAACATTTTAGAAACAAGTTAATTTTTAAGCAAACAAGGTTATAATTTTAAA
GTCATAAACAAGGAGCGATC

Downstream 100 bases:

>100_bases
AAATTTATTAAGGAGAAACAATGGATACAATAAACATAGGAATTTTAACCCTAAGCGATAGAGCAAGTAGTGGTATATAC
GAAGATAAAGCCACTGCTGA

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MLYIYIKTQNALVQRINFNLDSQELPQNILWIDLLHPSAAEIAFISSEFNLEFPTKEEREEIELSAKYWEDNATITINAH
FLVRDLKNDEEDRNLIKLRTEIVTFATAKNILFTIRYNEFSTFEEIQARILASPKNFEDGFDIIDKMFEVRVEKDADLLE
WIDKEARRLRTSVLEKKDEYSYDEMLKDISSLQELNMRVRDSLFDKRRAMTSLLKSDKIDKDIKQNLTIVLKDLNSLVEF
SVSQLNILDNIQTILASQINIEQNKIIKIFTVATVAMMPPTLIGTVYGMNFKFMPELELHYAYPIVLGVMVISIILPLVV
FKKKGWL

Sequences:

>Translated_327_residues
MLYIYIKTQNALVQRINFNLDSQELPQNILWIDLLHPSAAEIAFISSEFNLEFPTKEEREEIELSAKYWEDNATITINAH
FLVRDLKNDEEDRNLIKLRTEIVTFATAKNILFTIRYNEFSTFEEIQARILASPKNFEDGFDIIDKMFEVRVEKDADLLE
WIDKEARRLRTSVLEKKDEYSYDEMLKDISSLQELNMRVRDSLFDKRRAMTSLLKSDKIDKDIKQNLTIVLKDLNSLVEF
SVSQLNILDNIQTILASQINIEQNKIIKIFTVATVAMMPPTLIGTVYGMNFKFMPELELHYAYPIVLGVMVISIILPLVV
FKKKGWL
>Mature_327_residues
MLYIYIKTQNALVQRINFNLDSQELPQNILWIDLLHPSAAEIAFISSEFNLEFPTKEEREEIELSAKYWEDNATITINAH
FLVRDLKNDEEDRNLIKLRTEIVTFATAKNILFTIRYNEFSTFEEIQARILASPKNFEDGFDIIDKMFEVRVEKDADLLE
WIDKEARRLRTSVLEKKDEYSYDEMLKDISSLQELNMRVRDSLFDKRRAMTSLLKSDKIDKDIKQNLTIVLKDLNSLVEF
SVSQLNILDNIQTILASQINIEQNKIIKIFTVATVAMMPPTLIGTVYGMNFKFMPELELHYAYPIVLGVMVISIILPLVV
FKKKGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=302, Percent_Identity=31.4569536423841, Blast_Score=166, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 38203; Mature: 38203

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYIYIKTQNALVQRINFNLDSQELPQNILWIDLLHPSAAEIAFISSEFNLEFPTKEERE
CEEEEEECCHHHHHHHCCCCCHHHCCCCEEEEEEECCCCCCEEEEECCCCEECCCCHHHH
EIELSAKYWEDNATITINAHFLVRDLKNDEEDRNLIKLRTEIVTFATAKNILFTIRYNEF
HHHEEHEEECCCCEEEEEEHEEEEECCCCCHHHHHHHHHHHHHHHEECCCEEEEEEECCC
STFEEIQARILASPKNFEDGFDIIDKMFEVRVEKDADLLEWIDKEARRLRTSVLEKKDEY
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCC
SYDEMLKDISSLQELNMRVRDSLFDKRRAMTSLLKSDKIDKDIKQNLTIVLKDLNSLVEF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
SVSQLNILDNIQTILASQINIEQNKIIKIFTVATVAMMPPTLIGTVYGMNFKFMPELELH
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCHHHHHHHHCCCEEECCCCHHH
YAYPIVLGVMVISIILPLVVFKKKGWL
HHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLYIYIKTQNALVQRINFNLDSQELPQNILWIDLLHPSAAEIAFISSEFNLEFPTKEERE
CEEEEEECCHHHHHHHCCCCCHHHCCCCEEEEEEECCCCCCEEEEECCCCEECCCCHHHH
EIELSAKYWEDNATITINAHFLVRDLKNDEEDRNLIKLRTEIVTFATAKNILFTIRYNEF
HHHEEHEEECCCCEEEEEEHEEEEECCCCCHHHHHHHHHHHHHHHEECCCEEEEEEECCC
STFEEIQARILASPKNFEDGFDIIDKMFEVRVEKDADLLEWIDKEARRLRTSVLEKKDEY
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCC
SYDEMLKDISSLQELNMRVRDSLFDKRRAMTSLLKSDKIDKDIKQNLTIVLKDLNSLVEF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
SVSQLNILDNIQTILASQINIEQNKIIKIFTVATVAMMPPTLIGTVYGMNFKFMPELELH
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCHHHHHHHHCCCEEECCCCHHH
YAYPIVLGVMVISIILPLVVFKKKGWL
HHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]