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The map label for this gene is ftsZ [H]

Identifier: 57236999

GI number: 57236999

Start: 732673

End: 733785

Strand: Direct

Name: ftsZ [H]

Synonym: CJE0795

Alternate gene names: 57236999

Gene position: 732673-733785 (Clockwise)

Preceding gene: 57236998

Following gene: 57237000

Centisome position: 41.21

GC content: 35.85

Gene sequence:

>1113_bases
ATGAGTGAATTTTTAGTAGAAGAAATGCAACATAATAAAGGTGCAAAAATTAAGGTTATAGGCTGCGGTGGCGGTGGCGG
TAATATGATCAATCATATGGTTAAAATGGGATTAAATGATCTTGATTTAATTGCAGCGAATACTGATGCACAAGCTATTT
CAATTTCATTAGCAAAAACTAAAATTCAACTTGGCGAGAAAAAAACTAAAGGTTTGGGCGCTGGTATGCTTCCTGAAGTA
GGTGCAGAAAGCGCTAGAGAAAGTTTTGAAGAAATAAAAGCAAGTCTTAGTCAAAGTGATATTGTATTTATTGCTTCAGG
TTTTGGTGGAGGTACTGGAACGGGTGCCACTCCAGTTATTGCACAAGCAGCTAAAGAGATTGGAGCTTTAACTGTTTCTG
TTGTAACTATGCCTTTTGCATTCGAAGGAAAACAAAGAAAAAAACTTGCTGAAAGCGGTCTCCTTGAGCTTAAAAAAGAA
AGTGATTCTATTCTTGTAATTCAAAATGAAAAATTATTGAGCATTATTGATAAAAAAGCAGGCATTAAAGATGCTTTTAG
GTTGGTTGATGATATTTTAGCTCGTGCTGTAAAAGGTATGGTGTCTATCTTACTTGATAATGGAGATATTAATGTTGACT
TTGCGGATGTAAGAACCATCATGAGTCATCGCGGACTCGCGCTTATGGGTGTTGGTAGTGCTAGCGGTGAAAATGCTATA
GAAGAGGCTCTTTCAAACGCTATAGAATCTCCTTTGCTTGATGGAATGGATATTAAAGGTGCCAAGGGAGTTATTTTACA
TTTTAAAACAAGTTCTAATTGCTCTTTGTTTGAAATTTCGGCAGCAGCAAATAGTATACAAGAAATTGTTGATGAAAATG
CTAAGATTATTTTTGGTTCTACCACAGATGATAGCATGGAAGATAGAGTTGAAGTAACTATTATTGCGACAGGGTTTGAA
GATAAAGATACAGTAGCTAAAAAATCTACCGAAGAAGCTCAAGCTTCTAAGAAAAATCCTTATTTAAGTCTTAAAAAGGT
AAGCGGTGGTTACGATGAAGAGATAATGGCGCAAATTGAAACACCAACTTTCTTGCGTCGTCAAATGGATTAA

Upstream 100 bases:

>100_bases
AGAACAATTAGATTTTAAAGAGCCAAAAGAAAAAAAACCTAGTGTTTTTTCAAATATCTGGCATAAAATTATGAATCAAT
TTTAACAAGGAGAAATTTTT

Downstream 100 bases:

>100_bases
AATTGATTTTTAAAGCAAGATTGAGTCAAATCTTGCTTTTTATAGTTTAAAATTCTCTCCTAATAATCTTTCAAATATTT
ATTTTTCTTTGTTTTTAAAA

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSEFLVEEMQHNKGAKIKVIGCGGGGGNMINHMVKMGLNDLDLIAANTDAQAISISLAKTKIQLGEKKTKGLGAGMLPEV
GAESARESFEEIKASLSQSDIVFIASGFGGGTGTGATPVIAQAAKEIGALTVSVVTMPFAFEGKQRKKLAESGLLELKKE
SDSILVIQNEKLLSIIDKKAGIKDAFRLVDDILARAVKGMVSILLDNGDINVDFADVRTIMSHRGLALMGVGSASGENAI
EEALSNAIESPLLDGMDIKGAKGVILHFKTSSNCSLFEISAAANSIQEIVDENAKIIFGSTTDDSMEDRVEVTIIATGFE
DKDTVAKKSTEEAQASKKNPYLSLKKVSGGYDEEIMAQIETPTFLRRQMD

Sequences:

>Translated_370_residues
MSEFLVEEMQHNKGAKIKVIGCGGGGGNMINHMVKMGLNDLDLIAANTDAQAISISLAKTKIQLGEKKTKGLGAGMLPEV
GAESARESFEEIKASLSQSDIVFIASGFGGGTGTGATPVIAQAAKEIGALTVSVVTMPFAFEGKQRKKLAESGLLELKKE
SDSILVIQNEKLLSIIDKKAGIKDAFRLVDDILARAVKGMVSILLDNGDINVDFADVRTIMSHRGLALMGVGSASGENAI
EEALSNAIESPLLDGMDIKGAKGVILHFKTSSNCSLFEISAAANSIQEIVDENAKIIFGSTTDDSMEDRVEVTIIATGFE
DKDTVAKKSTEEAQASKKNPYLSLKKVSGGYDEEIMAQIETPTFLRRQMD
>Mature_369_residues
SEFLVEEMQHNKGAKIKVIGCGGGGGNMINHMVKMGLNDLDLIAANTDAQAISISLAKTKIQLGEKKTKGLGAGMLPEVG
AESARESFEEIKASLSQSDIVFIASGFGGGTGTGATPVIAQAAKEIGALTVSVVTMPFAFEGKQRKKLAESGLLELKKES
DSILVIQNEKLLSIIDKKAGIKDAFRLVDDILARAVKGMVSILLDNGDINVDFADVRTIMSHRGLALMGVGSASGENAIE
EALSNAIESPLLDGMDIKGAKGVILHFKTSSNCSLFEISAAANSIQEIVDENAKIIFGSTTDDSMEDRVEVTIIATGFED
KDTVAKKSTEEAQASKKNPYLSLKKVSGGYDEEIMAQIETPTFLRRQMD

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=360, Percent_Identity=39.4444444444444, Blast_Score=236, Evalue=1e-63,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 39278; Mature: 39146

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFLVEEMQHNKGAKIKVIGCGGGGGNMINHMVKMGLNDLDLIAANTDAQAISISLAKT
CCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEHH
KIQLGEKKTKGLGAGMLPEVGAESARESFEEIKASLSQSDIVFIASGFGGGTGTGATPVI
HHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHH
AQAAKEIGALTVSVVTMPFAFEGKQRKKLAESGLLELKKESDSILVIQNEKLLSIIDKKA
HHHHHHHCCEEEEEEEECEEECCHHHHHHHHHHHHHEECCCCCEEEEECCHHHHHHHHHC
GIKDAFRLVDDILARAVKGMVSILLDNGDINVDFADVRTIMSHRGLALMGVGSASGENAI
CHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEHHHHHHHHHHCCEEEEECCCCCCHHHH
EEALSNAIESPLLDGMDIKGAKGVILHFKTSSNCSLFEISAAANSIQEIVDENAKIIFGS
HHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCEEEEHHHHHHHHHHHCCCCEEEEEC
TTDDSMEDRVEVTIIATGFEDKDTVAKKSTEEAQASKKNPYLSLKKVSGGYDEEIMAQIE
CCCCCCCCCEEEEEEEECCCCCHHHHHCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHCC
TPTFLRRQMD
CCHHHHHCCC
>Mature Secondary Structure 
SEFLVEEMQHNKGAKIKVIGCGGGGGNMINHMVKMGLNDLDLIAANTDAQAISISLAKT
CHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEHH
KIQLGEKKTKGLGAGMLPEVGAESARESFEEIKASLSQSDIVFIASGFGGGTGTGATPVI
HHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHH
AQAAKEIGALTVSVVTMPFAFEGKQRKKLAESGLLELKKESDSILVIQNEKLLSIIDKKA
HHHHHHHCCEEEEEEEECEEECCHHHHHHHHHHHHHEECCCCCEEEEECCHHHHHHHHHC
GIKDAFRLVDDILARAVKGMVSILLDNGDINVDFADVRTIMSHRGLALMGVGSASGENAI
CHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEHHHHHHHHHHCCEEEEECCCCCCHHHH
EEALSNAIESPLLDGMDIKGAKGVILHFKTSSNCSLFEISAAANSIQEIVDENAKIIFGS
HHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCEEEEHHHHHHHHHHHCCCCEEEEEC
TTDDSMEDRVEVTIIATGFEDKDTVAKKSTEEAQASKKNPYLSLKKVSGGYDEEIMAQIE
CCCCCCCCCEEEEEEEECCCCCHHHHHCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHCC
TPTFLRRQMD
CCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685; 1490605 [H]