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The map label for this gene is argG [H]

Identifier: 57236975

GI number: 57236975

Start: 700224

End: 701444

Strand: Reverse

Name: argG [H]

Synonym: CJE0767

Alternate gene names: 57236975

Gene position: 701444-700224 (Counterclockwise)

Preceding gene: 57236983

Following gene: 57236974

Centisome position: 39.46

GC content: 36.69

Gene sequence:

>1221_bases
ATGAAAAATGAAGTAAAAAAAGTAGTTTTAGCGTATTCTGGGGGGCTTGATACGAGCATTATTTTAAAATGGCTTCAAGA
TGAGTATAATTGTGAAGTTGTAACTTTTACAGCAGATATTGGTCAAGGTGAAGAACTCGAACCTGCAAGAAAAAAAGCCC
TTTCTTTAGGCATAAAAGAAGAAAATATTTTCATTAAAGATTTAAGAGATGAATTTGTTAAAGATTATGTATTTCCTATG
TTTAGAGCCAATGCGATTTATGAAGGAGAATATCTTTTAGGAACAAGTATAGCAAGACCACTTATAGCAAAAACTCAAGC
ACAAATCGCCCTGCAAACAGGTGCTGATGCAGTAAGTCATGGTGCCACAGGTAAAGGAAATGATCAAGTGCGTTTTGAAC
TTGGTTATCTTGCTTTTAATCCCGATTTAAAAATCATCGCTCCATGGCGTGAGTGGGATTTAAACAGTCGTGAAAAACTC
CTTGCTTATGCACAAAAACACGGTATTGATATTTCTAAGAAAAAAGGAAAATCTCCTTATTCTATGGACGCAAATTTACT
TCATATTTCTTACGAAGGACTTGTCTTAGAAGATCCTGCACACGCACCTGAAGAAGATATGTGGAGATGGAGTAAAAGCC
CAAAAGATGCTCCAAATGAAAGTGAAATTATAGAACTTGATTTCCAAAAAGGAGATTTAGTAGCGATAAATGGAGAAAAA
CTAAGTCCTGCAGGACTTTTAACCAAACTTAACGAACTAGGCTGCAAACACGGTATAGGACGCCTTGATATAGTAGAAAA
TCGCTATGTAGGTATGAAAAGCCGTGGTTGTTACGAAACACCAGGTGGTACCATACTTTTAAAAGCACACAGAGCGCTTG
AAAGCATCACGCTTGATAGAGAAGCAGCACACTTAAAAGATGAACTCATGCCAAAATACGCGAGTTTAATTTATAATGGC
TATTGGTTCTCGCCTGAAAGAATGATGCTTCAAGCCTTAATCGATGAGTCTCAAATTCACGCCAATGGCAGAGTAAAACT
CGAGCTTTATAAAGGCAATGTGATAGTTATAGGACGCGAAAGTTCGAACGATAGCTTGTTTAACGCAGCTTATTGTACTT
TTGAAGAAGATGAAGTGTATAATCAAAAAGACGCAGCAGGCTTTATCAAGCTTAATGCTTTGCGTTTTATCATCGCAGGA
AAAAATGGAAGAAAATTTTAA

Upstream 100 bases:

>100_bases
TGCTTTATTTTTTTAAGAAAATAGCAAGTAAAAACTTTTCTTTAATGAAATTTGGATACAATTTTACAATTTTCAAATCT
ATTTTAACAAAGGATATCTT

Downstream 100 bases:

>100_bases
TAAAGGAATAAAATGAAAGTATTATTAATCAAAGATGTAAAAGCACTTGGAAAAGCAGGAGAAATAAAAGAAGTAAAAGA
CGGCTACGGACAAAATTTCT

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MKNEVKKVVLAYSGGLDTSIILKWLQDEYNCEVVTFTADIGQGEELEPARKKALSLGIKEENIFIKDLRDEFVKDYVFPM
FRANAIYEGEYLLGTSIARPLIAKTQAQIALQTGADAVSHGATGKGNDQVRFELGYLAFNPDLKIIAPWREWDLNSREKL
LAYAQKHGIDISKKKGKSPYSMDANLLHISYEGLVLEDPAHAPEEDMWRWSKSPKDAPNESEIIELDFQKGDLVAINGEK
LSPAGLLTKLNELGCKHGIGRLDIVENRYVGMKSRGCYETPGGTILLKAHRALESITLDREAAHLKDELMPKYASLIYNG
YWFSPERMMLQALIDESQIHANGRVKLELYKGNVIVIGRESSNDSLFNAAYCTFEEDEVYNQKDAAGFIKLNALRFIIAG
KNGRKF

Sequences:

>Translated_406_residues
MKNEVKKVVLAYSGGLDTSIILKWLQDEYNCEVVTFTADIGQGEELEPARKKALSLGIKEENIFIKDLRDEFVKDYVFPM
FRANAIYEGEYLLGTSIARPLIAKTQAQIALQTGADAVSHGATGKGNDQVRFELGYLAFNPDLKIIAPWREWDLNSREKL
LAYAQKHGIDISKKKGKSPYSMDANLLHISYEGLVLEDPAHAPEEDMWRWSKSPKDAPNESEIIELDFQKGDLVAINGEK
LSPAGLLTKLNELGCKHGIGRLDIVENRYVGMKSRGCYETPGGTILLKAHRALESITLDREAAHLKDELMPKYASLIYNG
YWFSPERMMLQALIDESQIHANGRVKLELYKGNVIVIGRESSNDSLFNAAYCTFEEDEVYNQKDAAGFIKLNALRFIIAG
KNGRKF
>Mature_406_residues
MKNEVKKVVLAYSGGLDTSIILKWLQDEYNCEVVTFTADIGQGEELEPARKKALSLGIKEENIFIKDLRDEFVKDYVFPM
FRANAIYEGEYLLGTSIARPLIAKTQAQIALQTGADAVSHGATGKGNDQVRFELGYLAFNPDLKIIAPWREWDLNSREKL
LAYAQKHGIDISKKKGKSPYSMDANLLHISYEGLVLEDPAHAPEEDMWRWSKSPKDAPNESEIIELDFQKGDLVAINGEK
LSPAGLLTKLNELGCKHGIGRLDIVENRYVGMKSRGCYETPGGTILLKAHRALESITLDREAAHLKDELMPKYASLIYNG
YWFSPERMMLQALIDESQIHANGRVKLELYKGNVIVIGRESSNDSLFNAAYCTFEEDEVYNQKDAAGFIKLNALRFIIAG
KNGRKF

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=398, Percent_Identity=46.7336683417085, Blast_Score=343, Evalue=1e-94,
Organism=Homo sapiens, GI16950633, Length=398, Percent_Identity=46.7336683417085, Blast_Score=343, Evalue=1e-94,
Organism=Escherichia coli, GI1789563, Length=414, Percent_Identity=28.5024154589372, Blast_Score=125, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6324514, Length=404, Percent_Identity=44.5544554455446, Blast_Score=347, Evalue=2e-96,
Organism=Drosophila melanogaster, GI21358151, Length=403, Percent_Identity=44.6650124069479, Blast_Score=337, Evalue=6e-93,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 45604; Mature: 45604

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNEVKKVVLAYSGGLDTSIILKWLQDEYNCEVVTFTADIGQGEELEPARKKALSLGIKE
CCCHHEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCC
ENIFIKDLRDEFVKDYVFPMFRANAIYEGEYLLGTSIARPLIAKTQAQIALQTGADAVSH
CCEEHHHHHHHHHHHHHHHHHHCCEEECCCEEECHHHHHHHHHHHHHEEEEECCCHHHHC
GATGKGNDQVRFELGYLAFNPDLKIIAPWREWDLNSREKLLAYAQKHGIDISKKKGKSPY
CCCCCCCCEEEEEEEEEEECCCEEEEECHHHCCCCCHHHHHHHHHHHCCCCHHHCCCCCC
SMDANLLHISYEGLVLEDPAHAPEEDMWRWSKSPKDAPNESEIIELDFQKGDLVAINGEK
CCCCEEEEEEECCEEEECCCCCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEECCCC
LSPAGLLTKLNELGCKHGIGRLDIVENRYVGMKSRGCYETPGGTILLKAHRALESITLDR
CCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEECCCCEEEEEEHHHHHHHHCCH
EAAHLKDELMPKYASLIYNGYWFSPERMMLQALIDESQIHANGRVKLELYKGNVIVIGRE
HHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHCHHHCCCCCEEEEEEEECCEEEEEEC
SSNDSLFNAAYCTFEEDEVYNQKDAAGFIKLNALRFIIAGKNGRKF
CCCCCEEEEEEEEECHHHHCCCCCCCCEEEEEEEEEEEECCCCCCC
>Mature Secondary Structure
MKNEVKKVVLAYSGGLDTSIILKWLQDEYNCEVVTFTADIGQGEELEPARKKALSLGIKE
CCCHHEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCC
ENIFIKDLRDEFVKDYVFPMFRANAIYEGEYLLGTSIARPLIAKTQAQIALQTGADAVSH
CCEEHHHHHHHHHHHHHHHHHHCCEEECCCEEECHHHHHHHHHHHHHEEEEECCCHHHHC
GATGKGNDQVRFELGYLAFNPDLKIIAPWREWDLNSREKLLAYAQKHGIDISKKKGKSPY
CCCCCCCCEEEEEEEEEEECCCEEEEECHHHCCCCCHHHHHHHHHHHCCCCHHHCCCCCC
SMDANLLHISYEGLVLEDPAHAPEEDMWRWSKSPKDAPNESEIIELDFQKGDLVAINGEK
CCCCEEEEEEECCEEEECCCCCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEECCCC
LSPAGLLTKLNELGCKHGIGRLDIVENRYVGMKSRGCYETPGGTILLKAHRALESITLDR
CCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEECCCCEEEEEEHHHHHHHHCCH
EAAHLKDELMPKYASLIYNGYWFSPERMMLQALIDESQIHANGRVKLELYKGNVIVIGRE
HHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHCHHHCCCCCEEEEEEEECCEEEEEEC
SSNDSLFNAAYCTFEEDEVYNQKDAAGFIKLNALRFIIAGKNGRKF
CCCCCEEEEEEEEECHHHHCCCCCCCCEEEEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA