Click here to switch to the map view.

The map label for this gene is dtpT [H]

Identifier: 57236967

GI number: 57236967

Start: 692038

End: 693591

Strand: Reverse

Name: dtpT [H]

Synonym: CJE0757

Alternate gene names: 57236967

Gene position: 693591-692038 (Counterclockwise)

Preceding gene: 57236968

Following gene: 57236966

Centisome position: 39.01

GC content: 30.18

Gene sequence:

>1554_bases
TTGAGTAAAAATGTAAAAAATTTAGATACTTCATTTTTTGGACATCCAAAACCACTTTTATCTCTTTCACTTACTGAGCT
TTGGGAAAGATTTTCTTTTTACGGAATTCGTCCCTTGCTTTACCTTTTTATGATAGCAAGTTTTGAAAAAAGTGGAATGA
ACTTAAAACCTGAAGAAGCAAGTGCAATTATGGGAATTTTTGCAAGTTGTTTATATCTTGCTGCTTTGCCAGGTGGATGG
CTTGCGGACAATTACTTAGGACAAAAAAGAGCAATTTTACTAGGTGCTTTAACTATAGCATTTGGACATTTGTGCATAGC
CTTTTCTTATTTTAACAATAAAATGATTTTTGTTGGTATGGTTTTTTTGGTTATAGGTACAGGACTTTTTAAAACTTGTG
CTTCTGTAATGGTTGGAATGCTTTATAAAAAAAATGATGCAAGGCGTGACTCTGGTTTTACTCTTTTTTATATGTGCTTT
AATTTTGGTGCTTTTGTAGCTCCTTTAATTTGCGGCTTTTTACAAAAAGAATACGGATGGCATTTTGGTTTTGGTGCAGG
TGGGATTGGTATGCTTTTAGCGGTAATTATTTTCTACCTAAAAACTATGCCTGATTTAAAAGAATTTGATGAAAAAGTTG
GCATAGACTCTACTTGGGATAGACCAAGCAAAAAAAGCAAAAACGCATTTTACATCATCATTGTATCAGGTATTGTTTTG
CTTGGAGCAATATTTTTAATCCTTGGTGGTTTTATAAAATTAGATGCACAAGTTATTAATAAAAATATTATTCTAACTAT
CTTAGCTTGTGCTGGAATTTATTTTTTATATCTTTTCGCTTTTACTTCTTTAAAAATAGAAGAAAAAAGAAATTTAATTA
TTTTTATTGTTTTATTTTTAGCGGCTGCGTTATTTTGGTCAGTATATGAGCAACAATACACTTCTTTTAATTTTTTTGCA
GAAAAATTAACAGATAAAACCATATTAAATTATGAAATTCCTACAATATGGTTTCAATCTCTTGGAGGTTTATTTGTTAT
ACTTTTTGCACCTTTTAGTGCTTTTATATGGACTATATGTGCCAAAAATAATAAAGAAATTTCATCTATTATTAAATTTG
CATTAGGACTTTTGGGTGCAGCTTTGGCATTTTTAATAATGGCTTTAGCTTCAAATCATGCAATTAGTTTAAATGGCGAT
GCTAATACATTAAGAGAAAATTTAGAAAATTCATCACAAATTATTTTAGTTTCACCTTGGTGGCTTGTCAGTAGCTTTTT
GCTTATGGTTTTAGGAGAGCTTTGCCTTTCCCCTGTGGGACTTTCTATAATGACAAAAATTGCACCTAATTTAATTAAAT
CTCAAGTCATGGGACTTTGGTTTGTAGCAAGTGCATTAGGCAATGCTTTAGCTGGATTCATAGGTGGTAAAGCAAGTGAA
GAAAATATAGCTTATTTGCCAAATTTATTTTACCAATGTATGTGGATATTACTTGGTGCTGTTATAATTTTACTTATACT
CAAAAAACCTATCAATAAAATACTAAAAAATTAA

Upstream 100 bases:

>100_bases
GTAACATTATGATATAAATCATTTAAAAATATTACAAAGTTATACATATTTTTTAATTTCTTGTCTATAATTTATAAATA
AAAATACACAAAGGATATAA

Downstream 100 bases:

>100_bases
TATTAAGGAGAAAATATGAGTATTTACAAACAAAGAGTATTAGAACTTAGAAGATTAATGAAAGAAAATAATATTGACGC
CTATCTCATCTTAAGCGCGG

Product: di-/tripeptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MSKNVKNLDTSFFGHPKPLLSLSLTELWERFSFYGIRPLLYLFMIASFEKSGMNLKPEEASAIMGIFASCLYLAALPGGW
LADNYLGQKRAILLGALTIAFGHLCIAFSYFNNKMIFVGMVFLVIGTGLFKTCASVMVGMLYKKNDARRDSGFTLFYMCF
NFGAFVAPLICGFLQKEYGWHFGFGAGGIGMLLAVIIFYLKTMPDLKEFDEKVGIDSTWDRPSKKSKNAFYIIIVSGIVL
LGAIFLILGGFIKLDAQVINKNIILTILACAGIYFLYLFAFTSLKIEEKRNLIIFIVLFLAAALFWSVYEQQYTSFNFFA
EKLTDKTILNYEIPTIWFQSLGGLFVILFAPFSAFIWTICAKNNKEISSIIKFALGLLGAALAFLIMALASNHAISLNGD
ANTLRENLENSSQIILVSPWWLVSSFLLMVLGELCLSPVGLSIMTKIAPNLIKSQVMGLWFVASALGNALAGFIGGKASE
ENIAYLPNLFYQCMWILLGAVIILLILKKPINKILKN

Sequences:

>Translated_517_residues
MSKNVKNLDTSFFGHPKPLLSLSLTELWERFSFYGIRPLLYLFMIASFEKSGMNLKPEEASAIMGIFASCLYLAALPGGW
LADNYLGQKRAILLGALTIAFGHLCIAFSYFNNKMIFVGMVFLVIGTGLFKTCASVMVGMLYKKNDARRDSGFTLFYMCF
NFGAFVAPLICGFLQKEYGWHFGFGAGGIGMLLAVIIFYLKTMPDLKEFDEKVGIDSTWDRPSKKSKNAFYIIIVSGIVL
LGAIFLILGGFIKLDAQVINKNIILTILACAGIYFLYLFAFTSLKIEEKRNLIIFIVLFLAAALFWSVYEQQYTSFNFFA
EKLTDKTILNYEIPTIWFQSLGGLFVILFAPFSAFIWTICAKNNKEISSIIKFALGLLGAALAFLIMALASNHAISLNGD
ANTLRENLENSSQIILVSPWWLVSSFLLMVLGELCLSPVGLSIMTKIAPNLIKSQVMGLWFVASALGNALAGFIGGKASE
ENIAYLPNLFYQCMWILLGAVIILLILKKPINKILKN
>Mature_516_residues
SKNVKNLDTSFFGHPKPLLSLSLTELWERFSFYGIRPLLYLFMIASFEKSGMNLKPEEASAIMGIFASCLYLAALPGGWL
ADNYLGQKRAILLGALTIAFGHLCIAFSYFNNKMIFVGMVFLVIGTGLFKTCASVMVGMLYKKNDARRDSGFTLFYMCFN
FGAFVAPLICGFLQKEYGWHFGFGAGGIGMLLAVIIFYLKTMPDLKEFDEKVGIDSTWDRPSKKSKNAFYIIIVSGIVLL
GAIFLILGGFIKLDAQVINKNIILTILACAGIYFLYLFAFTSLKIEEKRNLIIFIVLFLAAALFWSVYEQQYTSFNFFAE
KLTDKTILNYEIPTIWFQSLGGLFVILFAPFSAFIWTICAKNNKEISSIIKFALGLLGAALAFLIMALASNHAISLNGDA
NTLRENLENSSQIILVSPWWLVSSFLLMVLGELCLSPVGLSIMTKIAPNLIKSQVMGLWFVASALGNALAGFIGGKASEE
NIAYLPNLFYQCMWILLGAVIILLILKKPINKILKN

Specific function: Proton-dependent uptake of di- or tri-peptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=406, Percent_Identity=22.4137931034483, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI21717816, Length=493, Percent_Identity=23.3265720081136, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI226371746, Length=387, Percent_Identity=21.7054263565891, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1789911, Length=513, Percent_Identity=28.2651072124756, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1787922, Length=483, Percent_Identity=28.5714285714286, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1790572, Length=479, Percent_Identity=27.1398747390397, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1786927, Length=479, Percent_Identity=26.7223382045929, Blast_Score=180, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17569141, Length=428, Percent_Identity=25.2336448598131, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71987453, Length=402, Percent_Identity=22.8855721393035, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24639583, Length=213, Percent_Identity=28.6384976525822, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24639585, Length=215, Percent_Identity=28.3720930232558, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24639581, Length=201, Percent_Identity=28.8557213930348, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 57456; Mature: 57325

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKNVKNLDTSFFGHPKPLLSLSLTELWERFSFYGIRPLLYLFMIASFEKSGMNLKPEEA
CCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHH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CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]