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The map label for this gene is ydjN [C]

Identifier: 57236937

GI number: 57236937

Start: 30265

End: 31650

Strand: Reverse

Name: ydjN [C]

Synonym: CJE0025

Alternate gene names: 57236937

Gene position: 31650-30265 (Counterclockwise)

Preceding gene: 57236938

Following gene: 57236934

Centisome position: 1.78

GC content: 31.17

Gene sequence:

>1386_bases
ATGGATAAACAATTTTTTCAAGATTTTCTAATGCTTTCACAAGCTCATACTATAACTACTCTTGCTATGCTTTGTGTTGT
TTTTTACGCATTAAAAAAAATGCGGGATATAAAAATCAATTTTTCTCTTCGCATGCTATTTGCGCTTTTAATGGGTTTGG
GGTTTGGTTTTGCTTTGCAATATTTGGCAAATTTTCCAGATGCTAAAGAAGCAAGTAATATTCTTTGGTATAGCGAAACA
AAACATTGGTTTGCATTTGTAAGTTCTGTTTTTGTAGCTTTTATAAAAATGCTGGTTGTTCCTCTTGTAAGTATTTGCAT
TATAAAAGTAATTATAGAAATTGATAAAAATATCAAAATATCCTCCTTGCTTGGAATAAGTCTTTTTTGGATACTCTTTA
GCACAGCCATAGCTGCAACCTTGGGTATATTTTTAGGTTATAGTTTTGATTTAGGAAGTAATTTTGCTATATATGAAGGA
AATAAACAAATTCGCGAAATTCAAACTTTTTCAAATATTATACTAGGGCTAATACCTAGCAACATCATTGCAGCTATTAA
TAAAGAAAATATTATAGCTATTGTTATTTTTTCTTTTTTTATAGGAATTAGTGCTAAAAAAATTTCTAAAAAAGAAGAGT
ATGAACAAGCCTTTAAAAGTTTTCATAATTTTATCCTAACCTTTTATAATATTATGATGAACATGACTGCTACAGTTATT
AGATTTATGCCTTATGCTGTAGTTTGTATGATGGCTAATGTGCTTTTAAGCAATGGTTTTGAAGCTATCAAAACAGCTGG
ACTTTTTATAATGCTTATTTATATAGCTATGTTAATAATGTTCGGGGTGCATTTTTTACTTCTTGCTTCACAAGGGCTAA
ACCCTATAAAATATGCAAAAAAAGCATTTCCTGTATGGTTATTTGCATTTAGCTCAAGATCTTCTTTGGGCACTTTGCCT
ATGACTACTTCAACTTTGCAAAATAAATTTGGAGTTAATTCAGCTATAGCTAATTTTGTAGCATCTATAGGTACAACAAC
AGGACTTAATGGTTGTGCGGGATATTTTCCAGCTTTAGCGGCAGTTTTTGTAGCTTTTGCTACACATACACATATTGATT
TTACATTTGCTTTAATGATAGTTTTGGTAGCTGTTATTGGATCCTTGGGTATAGCTGGAGTACCTGGAAGTGCAACTATG
GCAGCTTCTATTATGCTAGCAGGGATTGGATTTGGTAATAATTTTGTCATGCTAAGTTTGATTTTAGCTATAGATCCTAT
TATAGATATGGCAAGAACAGCAAGTAATGTCTCAGGAGCTATGACTTCGGCACTTTGTACTGCAAAAAATCTAAAAGCCC
TAGATAAAGAAATTTACAATTCTTAA

Upstream 100 bases:

>100_bases
ATTTAAAATATTGTTATGCTACCATTTATAAAATCAAGCTTTACGCAAGTATATTTTCATATACCTTGTGCTTGATTATA
GTTTCTTATAAGGACTTTTT

Downstream 100 bases:

>100_bases
TCTCTTAAAACCCAATATTTTTCATTGGGTTTTAGTATTTATTGGCAACCTTCACATTCTATGCTACGATCTGCAACATT
GACTTTTTCACTATCAGGGC

Product: sodium/dicarboxylate symporter

Products: NA

Alternate protein names: Transporter of cystine tcyP [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MDKQFFQDFLMLSQAHTITTLAMLCVVFYALKKMRDIKINFSLRMLFALLMGLGFGFALQYLANFPDAKEASNILWYSET
KHWFAFVSSVFVAFIKMLVVPLVSICIIKVIIEIDKNIKISSLLGISLFWILFSTAIAATLGIFLGYSFDLGSNFAIYEG
NKQIREIQTFSNIILGLIPSNIIAAINKENIIAIVIFSFFIGISAKKISKKEEYEQAFKSFHNFILTFYNIMMNMTATVI
RFMPYAVVCMMANVLLSNGFEAIKTAGLFIMLIYIAMLIMFGVHFLLLASQGLNPIKYAKKAFPVWLFAFSSRSSLGTLP
MTTSTLQNKFGVNSAIANFVASIGTTTGLNGCAGYFPALAAVFVAFATHTHIDFTFALMIVLVAVIGSLGIAGVPGSATM
AASIMLAGIGFGNNFVMLSLILAIDPIIDMARTASNVSGAMTSALCTAKNLKALDKEIYNS

Sequences:

>Translated_461_residues
MDKQFFQDFLMLSQAHTITTLAMLCVVFYALKKMRDIKINFSLRMLFALLMGLGFGFALQYLANFPDAKEASNILWYSET
KHWFAFVSSVFVAFIKMLVVPLVSICIIKVIIEIDKNIKISSLLGISLFWILFSTAIAATLGIFLGYSFDLGSNFAIYEG
NKQIREIQTFSNIILGLIPSNIIAAINKENIIAIVIFSFFIGISAKKISKKEEYEQAFKSFHNFILTFYNIMMNMTATVI
RFMPYAVVCMMANVLLSNGFEAIKTAGLFIMLIYIAMLIMFGVHFLLLASQGLNPIKYAKKAFPVWLFAFSSRSSLGTLP
MTTSTLQNKFGVNSAIANFVASIGTTTGLNGCAGYFPALAAVFVAFATHTHIDFTFALMIVLVAVIGSLGIAGVPGSATM
AASIMLAGIGFGNNFVMLSLILAIDPIIDMARTASNVSGAMTSALCTAKNLKALDKEIYNS
>Mature_461_residues
MDKQFFQDFLMLSQAHTITTLAMLCVVFYALKKMRDIKINFSLRMLFALLMGLGFGFALQYLANFPDAKEASNILWYSET
KHWFAFVSSVFVAFIKMLVVPLVSICIIKVIIEIDKNIKISSLLGISLFWILFSTAIAATLGIFLGYSFDLGSNFAIYEG
NKQIREIQTFSNIILGLIPSNIIAAINKENIIAIVIFSFFIGISAKKISKKEEYEQAFKSFHNFILTFYNIMMNMTATVI
RFMPYAVVCMMANVLLSNGFEAIKTAGLFIMLIYIAMLIMFGVHFLLLASQGLNPIKYAKKAFPVWLFAFSSRSSLGTLP
MTTSTLQNKFGVNSAIANFVASIGTTTGLNGCAGYFPALAAVFVAFATHTHIDFTFALMIVLVAVIGSLGIAGVPGSATM
AASIMLAGIGFGNNFVMLSLILAIDPIIDMARTASNVSGAMTSALCTAKNLKALDKEIYNS

Specific function: Mediates uptake of L-cystine, the oxidized form of L- cysteine [H]

COG id: COG1823

COG function: function code R; Predicted Na+/dicarboxylate symporter

Gene ontology:

Cell location: Membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI169790839, Length=306, Percent_Identity=25.8169934640523, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI40254478, Length=415, Percent_Identity=22.1686746987952, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI21314632, Length=299, Percent_Identity=26.4214046822742, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI223468564, Length=256, Percent_Identity=26.171875, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI223468566, Length=256, Percent_Identity=26.171875, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI194239697, Length=254, Percent_Identity=26.7716535433071, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4827012, Length=265, Percent_Identity=24.1509433962264, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI5032093, Length=256, Percent_Identity=26.171875, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI66773030, Length=260, Percent_Identity=24.6153846153846, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI301601644, Length=179, Percent_Identity=30.1675977653631, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1788024, Length=465, Percent_Identity=31.6129032258064, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI1790514, Length=448, Percent_Identity=25.8928571428571, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1789947, Length=396, Percent_Identity=23.2323232323232, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71983099, Length=432, Percent_Identity=22.6851851851852, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71983106, Length=432, Percent_Identity=22.6851851851852, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI193206505, Length=465, Percent_Identity=23.6559139784946, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71996953, Length=474, Percent_Identity=24.4725738396624, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193206654, Length=453, Percent_Identity=21.6335540838852, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17537407, Length=397, Percent_Identity=22.1662468513854, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583025, Length=415, Percent_Identity=24.8192771084337, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17137668, Length=415, Percent_Identity=24.8192771084337, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24583023, Length=415, Percent_Identity=24.8192771084337, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 50511; Mature: 50511

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA