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The map label for this gene is yciL [C]

Identifier: 57236895

GI number: 57236895

Start: 1756746

End: 1757507

Strand: Reverse

Name: yciL [C]

Synonym: CJE1878

Alternate gene names: 57236895

Gene position: 1757507-1756746 (Counterclockwise)

Preceding gene: 57236896

Following gene: 57236893

Centisome position: 98.86

GC content: 33.86

Gene sequence:

>762_bases
ATGAGAATTAATAAATTTATATCCCATAACACCCGCTATTCACGCCGTGAAGCCGATGAACTTATCAAACAAGGCTTAGT
AAAAATAAACAACAAAATTGCCCTTTTAAGCGATGAAGTTAAATTTGATGATAAAGTTTTTGTTAAAGGTAAAAGAGTAC
AAAAAAGAACGCAATTTAGCGTGATAATCTACCATAAACAAAAAGGCGAAATTGTCAGTAAAAAAGACGATCGTGGAAGA
AAAACTATATATGATACCTTGCCAAGACAATTTAGTACTTGGCTTAGCGTAGGTAGGCTGGATTATGCAAGTGAAGGCTT
ACTTTTGCTTACAGATTCTCCTGTGATTGCCGATGCTTTAATGCATAGCGATTTAGAAAGAGAATACTACCTTAAAGTTA
AAGGCACGGTGAGCAAACAAGTCATCGAAGCCATGCAAAATGGACTTGAGATTAAAAATGAAAAAAAAGGCGCACATGCA
AAAACTAAAATTACCTCTATGAGTTTTGCTCCTTTTATAGACTTTGAAATTTTTGGATCAAGTGGAGGCTATACTAAGCT
TAGAGTGGTTATAAATGAAGGTAAAAATAGAGAGCTTAGACGCTTTTTTGGACATTTTGATCTTGAAGTCATGGATCTTA
AGCGTGTTGCTTTTGGGGCTTTAGATCTTGGTATGTTGAAGGCGGGAAAACATCGTTATTTAGAAAATGGCGAATATGAA
AAATTAAGAGATTTTTTAAAATTTAATGGAATAAGATATTGA

Upstream 100 bases:

>100_bases
GAAAACACATCTTTAGAAAGATTAAAAAATACCCAACCATAGTTCCAACTATTTTTGTAATGTAAAAAAGGGCAAAAACG
CCCTTTTTAAGGAAGATCAA

Downstream 100 bases:

>100_bases
CCATTATATACAAAAATTTAAAAAATAATGATAATTTTTAAATTCTAAAAATTCTATTTTTATCCTTTTTAAAAGGAAAA
TAATAGAAAAATTTCATCAA

Product: RNA pseudouridylate synthase

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MRINKFISHNTRYSRREADELIKQGLVKINNKIALLSDEVKFDDKVFVKGKRVQKRTQFSVIIYHKQKGEIVSKKDDRGR
KTIYDTLPRQFSTWLSVGRLDYASEGLLLLTDSPVIADALMHSDLEREYYLKVKGTVSKQVIEAMQNGLEIKNEKKGAHA
KTKITSMSFAPFIDFEIFGSSGGYTKLRVVINEGKNRELRRFFGHFDLEVMDLKRVAFGALDLGMLKAGKHRYLENGEYE
KLRDFLKFNGIRY

Sequences:

>Translated_253_residues
MRINKFISHNTRYSRREADELIKQGLVKINNKIALLSDEVKFDDKVFVKGKRVQKRTQFSVIIYHKQKGEIVSKKDDRGR
KTIYDTLPRQFSTWLSVGRLDYASEGLLLLTDSPVIADALMHSDLEREYYLKVKGTVSKQVIEAMQNGLEIKNEKKGAHA
KTKITSMSFAPFIDFEIFGSSGGYTKLRVVINEGKNRELRRFFGHFDLEVMDLKRVAFGALDLGMLKAGKHRYLENGEYE
KLRDFLKFNGIRY
>Mature_253_residues
MRINKFISHNTRYSRREADELIKQGLVKINNKIALLSDEVKFDDKVFVKGKRVQKRTQFSVIIYHKQKGEIVSKKDDRGR
KTIYDTLPRQFSTWLSVGRLDYASEGLLLLTDSPVIADALMHSDLEREYYLKVKGTVSKQVIEAMQNGLEIKNEKKGAHA
KTKITSMSFAPFIDFEIFGSSGGYTKLRVVINEGKNRELRRFFGHFDLEVMDLKRVAFGALDLGMLKAGKHRYLENGEYE
KLRDFLKFNGIRY

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=239, Percent_Identity=30.1255230125523, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790453, Length=241, Percent_Identity=30.7053941908714, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 29297; Mature: 29297

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRINKFISHNTRYSRREADELIKQGLVKINNKIALLSDEVKFDDKVFVKGKRVQKRTQFS
CCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEECHHHHCCCEEE
VIIYHKQKGEIVSKKDDRGRKTIYDTLPRQFSTWLSVGRLDYASEGLLLLTDSPVIADAL
EEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHH
MHSDLEREYYLKVKGTVSKQVIEAMQNGLEIKNEKKGAHAKTKITSMSFAPFIDFEIFGS
HHCCCCCEEEEEEECCHHHHHHHHHHCCCEECCCCCCCCCCEEEEEEECCCEEEEEEECC
SGGYTKLRVVINEGKNRELRRFFGHFDLEVMDLKRVAFGALDLGMLKAGKHRYLENGEYE
CCCCEEEEEEEECCCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCHHCCCCCCHH
KLRDFLKFNGIRY
HHHHHHHHCCCCC
>Mature Secondary Structure
MRINKFISHNTRYSRREADELIKQGLVKINNKIALLSDEVKFDDKVFVKGKRVQKRTQFS
CCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEECHHHHCCCEEE
VIIYHKQKGEIVSKKDDRGRKTIYDTLPRQFSTWLSVGRLDYASEGLLLLTDSPVIADAL
EEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHH
MHSDLEREYYLKVKGTVSKQVIEAMQNGLEIKNEKKGAHAKTKITSMSFAPFIDFEIFGS
HHCCCCCEEEEEEECCHHHHHHHHHHCCCEECCCCCCCCCCEEEEEEECCCEEEEEEECC
SGGYTKLRVVINEGKNRELRRFFGHFDLEVMDLKRVAFGALDLGMLKAGKHRYLENGEYE
CCCCEEEEEEEECCCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCHHCCCCCCHH
KLRDFLKFNGIRY
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]