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The map label for this gene is hyuA [H]

Identifier: 21228698

GI number: 21228698

Start: 3091624

End: 3093621

Strand: Reverse

Name: hyuA [H]

Synonym: MM_2596

Alternate gene names: 21228698

Gene position: 3093621-3091624 (Counterclockwise)

Preceding gene: 21228699

Following gene: 21228697

Centisome position: 75.52

GC content: 47.95

Gene sequence:

>1998_bases
ATGGCATACAGTCTTGGCATTGACGCAGGCGGGACCTATACTGATTCTATATTAATCCGTAATTCGGATGGAGAGGTTAT
TGGTTCTAACAAGTCACTCACGACATATCCAGACCTTCTGGAAGGAATAATGAAATCAATTGACGGGCTTAACCAGGAAA
AACTGAAACTTGTGACCCTGGTTTCGGTTTCCACAACTCTTGCAACCAATACTATCCTTGAAAAAACAGGATATCCCGTG
GGACTGATCCTTGTAGGCAACTACGAAATCCCTGAGGACTCGGAGATTGAAAATTGCATAATGGTGCAGGGTGGGCACGA
TAGCCGCGGAGATGAAGTGGCACCCCTTGACCTTTCCGCAGTTGAGAGCTTTGTTCTGGGGCTGAAGGGCAGGGTCTCGG
CATTTGCAGTTTCTTCATACTTCAGTGTCCGCAACCCTGAACATGAACTGCAGATAAAAGCCCTGATTCAGGAACTTACA
GGACTTCCTGTAGTCTGCGGGCATGAACTTGCTCAGGCACTGGGAGCATATGAAAGAGGGGTTACGGCTTACCTTAACGC
CCAGCTTCTTCCGGTAGCAGAGGGTTTTCTGAAAACCGTTGTCTGTGAGATAGAGAGAAGAGGGCTTGAGCCCAGAATTG
CGATGCTCCGCTGCGACGGGTCTGTTGTCAGCATGCACGAAGCGATGAGAAAGCCCATAGAATCGGTCTTTTCCGGGCCT
GCCGCAAGCCTGCTCGGGGCTTCATATCTGTCAGGATACGAGACCTGTGCAGTTATCGATGTAGGAGGGACAAGTACGGA
TGTGTCCCTGATCCACAGAGGGCTTCCTTACCTCAGTGAAACCGGGGCAGTTGTGGGAGGCTGGCAGACAAAGGTAAGGG
CACTCAGGATGGAGACTTCGGCAATGGGAGGAGACAGCCATATCTGGGTCCAGGCCAGTAAAACAAACATCGGACCGCGC
AGGGTTATTCCTCTCTGCAGGGCTGCCGTACTTTACCCTTCATTTCTGAGTTCTCTGAAAAAACGCTGGATTCCCGACAA
GCTCAAATTAAATGAACATATTCAGGCAACAAAGTTTTTTGTAAGAACAAAGCAGGAGCCTGTTAACCTGACAAGGGAAG
AAAAGGAGCTCCTTGCCCTCATAAAAAATGAGCCTCTTTCTCTCAAAGACATTTACTGGGACAGAAACATCCTGCCTTCT
AAAAAAGTGATGGACTCTCTTATCCAGAAAAGGCTTGTTCAGGCTATTGGCTTTACCCCAACAGACGCCCTTCATGTGCT
GGGAGAATATACCGAATGGAACTCCGAAGCCTCGGAAATAGGGGCTACACTGCTTGCAAACTTTTTAGGGACTGAAAAGC
AGGAATTCTGCTTAAATGTAAAGCGGCTTTTCGCCCGGAATATGGCAAAAGATCTCGTTTCCTTCCTCATGGAAGGGGTT
GACAGGAACGAAATTGAAAAAATGCTCGAATGCAGCTTATTCTCCCGCTTTAAGGTAGATATCCCGGTTGTACTTCTTGG
AGGACCGGTCAGGGCTTATATCGATGACCTGAAAAAAGTGATCGATGCCGAAATAATTGTCCCGGAATACTGTAAAGTAG
GAAATGCCGTGGGAGCCCTTGTGGGAAAAGGGACGAAACGTGTGGAAATCACAGTCCGTACAACTTACAGCGAGTCAAGG
TACGACATGAGGACAAAAGGGGTTTTTGTCTACACCCCTCTCGGAAGAAGACATTTCGTCCTGAGGAGCGAAGCCCTAGA
GTTTGCTGAGGAATTCGGAAGAAAGCTTGTCCTTGATTATATGGCTGAATCCGGGCTTTCTCCGGACCAGGTGACGGTCA
GTATGGAAAAGAAAGACATAATGGTCCAGACAGGGGACGTTCCCCTCGAAACCAGGTTTATCTTCGAAGGAATCTCAAAC
TCGGACGTATATGAAAAAGCAGTATCAGGGCATAAAGACCTTTGCATAAATCCTGATGGAATTGAAGAACTGACCTGA

Upstream 100 bases:

>100_bases
TACTCATAGGTTGCCAGTTATTTAACATGACAAAAATGGAACCCCATATGGCAATTATGAGTACCCTGAATACATAAAAA
CAAAATAAGGAAGCAAAAAA

Downstream 100 bases:

>100_bases
CACGGAAAATGGAATTTTCCATGTGGGCCCCGGGTTTAAATTGATGGTGAAAAAGGGTAAAGTTCATAACTCTCAGGTAC
ATTTGGAACATGAAATATTC

Product: hypothetical protein

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 665; Mature: 664

Protein sequence:

>665_residues
MAYSLGIDAGGTYTDSILIRNSDGEVIGSNKSLTTYPDLLEGIMKSIDGLNQEKLKLVTLVSVSTTLATNTILEKTGYPV
GLILVGNYEIPEDSEIENCIMVQGGHDSRGDEVAPLDLSAVESFVLGLKGRVSAFAVSSYFSVRNPEHELQIKALIQELT
GLPVVCGHELAQALGAYERGVTAYLNAQLLPVAEGFLKTVVCEIERRGLEPRIAMLRCDGSVVSMHEAMRKPIESVFSGP
AASLLGASYLSGYETCAVIDVGGTSTDVSLIHRGLPYLSETGAVVGGWQTKVRALRMETSAMGGDSHIWVQASKTNIGPR
RVIPLCRAAVLYPSFLSSLKKRWIPDKLKLNEHIQATKFFVRTKQEPVNLTREEKELLALIKNEPLSLKDIYWDRNILPS
KKVMDSLIQKRLVQAIGFTPTDALHVLGEYTEWNSEASEIGATLLANFLGTEKQEFCLNVKRLFARNMAKDLVSFLMEGV
DRNEIEKMLECSLFSRFKVDIPVVLLGGPVRAYIDDLKKVIDAEIIVPEYCKVGNAVGALVGKGTKRVEITVRTTYSESR
YDMRTKGVFVYTPLGRRHFVLRSEALEFAEEFGRKLVLDYMAESGLSPDQVTVSMEKKDIMVQTGDVPLETRFIFEGISN
SDVYEKAVSGHKDLCINPDGIEELT

Sequences:

>Translated_665_residues
MAYSLGIDAGGTYTDSILIRNSDGEVIGSNKSLTTYPDLLEGIMKSIDGLNQEKLKLVTLVSVSTTLATNTILEKTGYPV
GLILVGNYEIPEDSEIENCIMVQGGHDSRGDEVAPLDLSAVESFVLGLKGRVSAFAVSSYFSVRNPEHELQIKALIQELT
GLPVVCGHELAQALGAYERGVTAYLNAQLLPVAEGFLKTVVCEIERRGLEPRIAMLRCDGSVVSMHEAMRKPIESVFSGP
AASLLGASYLSGYETCAVIDVGGTSTDVSLIHRGLPYLSETGAVVGGWQTKVRALRMETSAMGGDSHIWVQASKTNIGPR
RVIPLCRAAVLYPSFLSSLKKRWIPDKLKLNEHIQATKFFVRTKQEPVNLTREEKELLALIKNEPLSLKDIYWDRNILPS
KKVMDSLIQKRLVQAIGFTPTDALHVLGEYTEWNSEASEIGATLLANFLGTEKQEFCLNVKRLFARNMAKDLVSFLMEGV
DRNEIEKMLECSLFSRFKVDIPVVLLGGPVRAYIDDLKKVIDAEIIVPEYCKVGNAVGALVGKGTKRVEITVRTTYSESR
YDMRTKGVFVYTPLGRRHFVLRSEALEFAEEFGRKLVLDYMAESGLSPDQVTVSMEKKDIMVQTGDVPLETRFIFEGISN
SDVYEKAVSGHKDLCINPDGIEELT
>Mature_664_residues
AYSLGIDAGGTYTDSILIRNSDGEVIGSNKSLTTYPDLLEGIMKSIDGLNQEKLKLVTLVSVSTTLATNTILEKTGYPVG
LILVGNYEIPEDSEIENCIMVQGGHDSRGDEVAPLDLSAVESFVLGLKGRVSAFAVSSYFSVRNPEHELQIKALIQELTG
LPVVCGHELAQALGAYERGVTAYLNAQLLPVAEGFLKTVVCEIERRGLEPRIAMLRCDGSVVSMHEAMRKPIESVFSGPA
ASLLGASYLSGYETCAVIDVGGTSTDVSLIHRGLPYLSETGAVVGGWQTKVRALRMETSAMGGDSHIWVQASKTNIGPRR
VIPLCRAAVLYPSFLSSLKKRWIPDKLKLNEHIQATKFFVRTKQEPVNLTREEKELLALIKNEPLSLKDIYWDRNILPSK
KVMDSLIQKRLVQAIGFTPTDALHVLGEYTEWNSEASEIGATLLANFLGTEKQEFCLNVKRLFARNMAKDLVSFLMEGVD
RNEIEKMLECSLFSRFKVDIPVVLLGGPVRAYIDDLKKVIDAEIIVPEYCKVGNAVGALVGKGTKRVEITVRTTYSESRY
DMRTKGVFVYTPLGRRHFVLRSEALEFAEEFGRKLVLDYMAESGLSPDQVTVSMEKKDIMVQTGDVPLETRFIFEGISNS
DVYEKAVSGHKDLCINPDGIEELT

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Drosophila melanogaster, GI45550492, Length=373, Percent_Identity=26.2734584450402, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 73325; Mature: 73194

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSLGIDAGGTYTDSILIRNSDGEVIGSNKSLTTYPDLLEGIMKSIDGLNQEKLKLVTL
CEEEEECCCCCCEECEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEE
VSVSTTLATNTILEKTGYPVGLILVGNYEIPEDSEIENCIMVQGGHDSRGDEVAPLDLSA
EEHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHH
VESFVLGLKGRVSAFAVSSYFSVRNPEHELQIKALIQELTGLPVVCGHELAQALGAYERG
HHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCC
VTAYLNAQLLPVAEGFLKTVVCEIERRGLEPRIAMLRCDGSVVSMHEAMRKPIESVFSGP
CEEEECCEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCC
AASLLGASYLSGYETCAVIDVGGTSTDVSLIHRGLPYLSETGAVVGGWQTKVRALRMETS
HHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCHHHCCCEEECHHHHHHHHHHHHH
AMGGDSHIWVQASKTNIGPRRVIPLCRAAVLYPSFLSSLKKRWIPDKLKLNEHIQATKFF
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCHHHHHHHHHHH
VRTKQEPVNLTREEKELLALIKNEPLSLKDIYWDRNILPSKKVMDSLIQKRLVQAIGFTP
HHCCCCCCCCCHHHHHHHHHHCCCCCCHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCC
TDALHVLGEYTEWNSEASEIGATLLANFLGTEKQEFCLNVKRLFARNMAKDLVSFLMEGV
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DRNEIEKMLECSLFSRFKVDIPVVLLGGPVRAYIDDLKKVIDAEIIVPEYCKVGNAVGAL
CHHHHHHHHHHHHHHHEECCCCEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHH
VGKGTKRVEITVRTTYSESRYDMRTKGVFVYTPLGRRHFVLRSEALEFAEEFGRKLVLDY
HCCCCEEEEEEEEEECCCCCCCCEECCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHH
MAESGLSPDQVTVSMEKKDIMVQTGDVPLETRFIFEGISNSDVYEKAVSGHKDLCINPDG
HHHCCCCCCCEEEEEECCEEEEEECCCCEEEHHEECCCCCCHHHHHHHCCCCCEEECCCC
IEELT
HHHCC
>Mature Secondary Structure 
AYSLGIDAGGTYTDSILIRNSDGEVIGSNKSLTTYPDLLEGIMKSIDGLNQEKLKLVTL
EEEEECCCCCCEECEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEE
VSVSTTLATNTILEKTGYPVGLILVGNYEIPEDSEIENCIMVQGGHDSRGDEVAPLDLSA
EEHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHH
VESFVLGLKGRVSAFAVSSYFSVRNPEHELQIKALIQELTGLPVVCGHELAQALGAYERG
HHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCC
VTAYLNAQLLPVAEGFLKTVVCEIERRGLEPRIAMLRCDGSVVSMHEAMRKPIESVFSGP
CEEEECCEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCC
AASLLGASYLSGYETCAVIDVGGTSTDVSLIHRGLPYLSETGAVVGGWQTKVRALRMETS
HHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCHHHCCCEEECHHHHHHHHHHHHH
AMGGDSHIWVQASKTNIGPRRVIPLCRAAVLYPSFLSSLKKRWIPDKLKLNEHIQATKFF
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCHHHHHHHHHHH
VRTKQEPVNLTREEKELLALIKNEPLSLKDIYWDRNILPSKKVMDSLIQKRLVQAIGFTP
HHCCCCCCCCCHHHHHHHHHHCCCCCCHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCC
TDALHVLGEYTEWNSEASEIGATLLANFLGTEKQEFCLNVKRLFARNMAKDLVSFLMEGV
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DRNEIEKMLECSLFSRFKVDIPVVLLGGPVRAYIDDLKKVIDAEIIVPEYCKVGNAVGAL
CHHHHHHHHHHHHHHHEECCCCEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHH
VGKGTKRVEITVRTTYSESRYDMRTKGVFVYTPLGRRHFVLRSEALEFAEEFGRKLVLDY
HCCCCEEEEEEEEEECCCCCCCCEECCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHH
MAESGLSPDQVTVSMEKKDIMVQTGDVPLETRFIFEGISNSDVYEKAVSGHKDLCINPDG
HHHCCCCCCCEEEEEECCEEEEEECCCCEEEHHEECCCCCCHHHHHHHCCCCCEEECCCC
IEELT
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]