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The map label for this gene is trkA [H]

Identifier: 21228603

GI number: 21228603

Start: 2980665

End: 2982092

Strand: Reverse

Name: trkA [H]

Synonym: MM_2501

Alternate gene names: 21228603

Gene position: 2982092-2980665 (Counterclockwise)

Preceding gene: 21228604

Following gene: 21228602

Centisome position: 72.8

GC content: 45.52

Gene sequence:

>1428_bases
ATGTACGTTTTTTTCTCCAAAGACTACTTAAGCAAGCAGGAGCAATCTATCTGGGAACAGTCTTTTCTTCGAGGGAATCT
TATGAAAGCGGTGGTTATCGGCGCAGGTGAAGTTGGGTATCATATAGCAAAGTTCCTTTCCCTCACACACGATGTGATCG
TTATTGAGAATGACGAGGATGCCCTGAGACGGGCGGATGAGCTTGATGTTCAGGTTGTGGAAGGAAACGGCGCAAATGCA
GATATTCTTGCAAGTGTCCTCCCTGATGTGGATATTCTCGTTGCTGTCACAGGAGTTGATGAAGTCAATATAGTTGCCTG
TATGACTGCAAAGCTTATATTAAGGGCACATCCGGGCTGGAAAGAAACAAAAACCATTGCCAGGGTCAGCAACCCTGACT
ATATTGATGTGCCGGTTACGTCCAGAGCTCAGGTAGGGGTAGACATAATGATATGCCCTGAACTTGCTCTTGCTTCGGAA
GTCGCTGAAGTGCTCTCAAATCCCTCTGCAATAGACGCGGAAATGTTTGCAGGGGGCAAAGTTCAGATGATGGAATTTGC
CATCCGCCCGGACAACAGGCTTGTTGGAAAGCGCATGCAGGATATTGAGCTTGAGGACTGCTGCATCGTCAGTGCAATAT
TCAGGAATAATGATATAATCATCCCTCACGGAGACGATTTCATAAAGGCAAATGACCACATGGTAGTTGTGGGCAAGCCC
AGGGCCATGGCGGACCTTGAAAACGTTTTCGGAAACGAAGGACCTCACCGGAATAGAATTCTTCTAATTGGCTGCGGAAT
TGTAGGCTTTTACCTTGCCAAGATTATAGATAAGGATGAGAACGCAGACCTCAAGGTTATCGAATACAGGAAAAGCCGCT
GTATAGAAGTGGCAGAGATGCTGGAAAATGCACTTATACTCAATGGGGACGGCACTGATGTCAACCTTCTCAGGGAAGAA
AACATAGAGGATATGGATGTCGTTATTGCGGTTACGGACAATGACGAAAAAAACCTTCTCTGTTCCCTGCTCGCAAAGCA
AATGGGAGCAAAAAAAGTAATCGCAAGAGCTGACCGCTCGGATTATGTCCCTCTTTTTGAGATGGTTGGGATCGACATTG
CAGTAAGCCCTAGAGAAGCAACCGTAAATGAAGTCCTCAAACTTACCATGGGAAAAGGCATAGAAGCCCTTGCGACAATT
GAAGGCGAAAAAGCGGAAATTATCGAATATACTGCATCAGGACAATCCAAAATCGTAGGAAAACCGCTTAGCAAGATAAA
GTTTCCCAAGGGTGCGATTGTTACCATGGTAGTCCATGATGATGATGTCATTATTCCCAGAGGGGAATTCATCATCAGGG
AAGGGGATAGAGTTATTATCTTTGCCCTTTCCTCCGCAGTCCGCTCTGTTGAGAAATTGTTTAAGTAA

Upstream 100 bases:

>100_bases
CCGAACAGCACACTTTACTTAAATTTTATCAGCCCTGGATTTTTATTCTTTGGTTCTTTTTCATTTTTTCCACATTAAAT
GATTTCTTAGAAATCCTCCC

Downstream 100 bases:

>100_bases
GCAATAAATACGAAAATCTTAAATACGAAACTCTTTCTTCATCTTCTTCATCTGTCCCTCATTTTTGAGAAGCTGTTTAA
GCAAGAAATAAATATGAATA

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA homolog 2 [H]

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MYVFFSKDYLSKQEQSIWEQSFLRGNLMKAVVIGAGEVGYHIAKFLSLTHDVIVIENDEDALRRADELDVQVVEGNGANA
DILASVLPDVDILVAVTGVDEVNIVACMTAKLILRAHPGWKETKTIARVSNPDYIDVPVTSRAQVGVDIMICPELALASE
VAEVLSNPSAIDAEMFAGGKVQMMEFAIRPDNRLVGKRMQDIELEDCCIVSAIFRNNDIIIPHGDDFIKANDHMVVVGKP
RAMADLENVFGNEGPHRNRILLIGCGIVGFYLAKIIDKDENADLKVIEYRKSRCIEVAEMLENALILNGDGTDVNLLREE
NIEDMDVVIAVTDNDEKNLLCSLLAKQMGAKKVIARADRSDYVPLFEMVGIDIAVSPREATVNEVLKLTMGKGIEALATI
EGEKAEIIEYTASGQSKIVGKPLSKIKFPKGAIVTMVVHDDDVIIPRGEFIIREGDRVIIFALSSAVRSVEKLFK

Sequences:

>Translated_475_residues
MYVFFSKDYLSKQEQSIWEQSFLRGNLMKAVVIGAGEVGYHIAKFLSLTHDVIVIENDEDALRRADELDVQVVEGNGANA
DILASVLPDVDILVAVTGVDEVNIVACMTAKLILRAHPGWKETKTIARVSNPDYIDVPVTSRAQVGVDIMICPELALASE
VAEVLSNPSAIDAEMFAGGKVQMMEFAIRPDNRLVGKRMQDIELEDCCIVSAIFRNNDIIIPHGDDFIKANDHMVVVGKP
RAMADLENVFGNEGPHRNRILLIGCGIVGFYLAKIIDKDENADLKVIEYRKSRCIEVAEMLENALILNGDGTDVNLLREE
NIEDMDVVIAVTDNDEKNLLCSLLAKQMGAKKVIARADRSDYVPLFEMVGIDIAVSPREATVNEVLKLTMGKGIEALATI
EGEKAEIIEYTASGQSKIVGKPLSKIKFPKGAIVTMVVHDDDVIIPRGEFIIREGDRVIIFALSSAVRSVEKLFK
>Mature_475_residues
MYVFFSKDYLSKQEQSIWEQSFLRGNLMKAVVIGAGEVGYHIAKFLSLTHDVIVIENDEDALRRADELDVQVVEGNGANA
DILASVLPDVDILVAVTGVDEVNIVACMTAKLILRAHPGWKETKTIARVSNPDYIDVPVTSRAQVGVDIMICPELALASE
VAEVLSNPSAIDAEMFAGGKVQMMEFAIRPDNRLVGKRMQDIELEDCCIVSAIFRNNDIIIPHGDDFIKANDHMVVVGKP
RAMADLENVFGNEGPHRNRILLIGCGIVGFYLAKIIDKDENADLKVIEYRKSRCIEVAEMLENALILNGDGTDVNLLREE
NIEDMDVVIAVTDNDEKNLLCSLLAKQMGAKKVIARADRSDYVPLFEMVGIDIAVSPREATVNEVLKLTMGKGIEALATI
EGEKAEIIEYTASGQSKIVGKPLSKIKFPKGAIVTMVVHDDDVIIPRGEFIIREGDRVIIFALSSAVRSVEKLFK

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=465, Percent_Identity=33.9784946236559, Blast_Score=229, Evalue=3e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 52237; Mature: 52237

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVFFSKDYLSKQEQSIWEQSFLRGNLMKAVVIGAGEVGYHIAKFLSLTHDVIVIENDED
CEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHCCCEEEEECCHH
ALRRADELDVQVVEGNGANADILASVLPDVDILVAVTGVDEVNIVACMTAKLILRAHPGW
HHHCCCCCCEEEEECCCCCHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHEECCCCC
KETKTIARVSNPDYIDVPVTSRAQVGVDIMICPELALASEVAEVLSNPSAIDAEMFAGGK
HHHHHEEECCCCCEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHCCCC
VQMMEFAIRPDNRLVGKRMQDIELEDCCIVSAIFRNNDIIIPHGDDFIKANDHMVVVGKP
EEEEEEEECCCCHHHHCHHCCCCCCHHHEEEHHHCCCCEEEECCCCEEECCCCEEEEECC
RAMADLENVFGNEGPHRNRILLIGCGIVGFYLAKIIDKDENADLKVIEYRKSRCIEVAEM
HHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHH
LENALILNGDGTDVNLLREENIEDMDVVIAVTDNDEKNLLCSLLAKQMGAKKVIARADRS
HCCEEEECCCCCCEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHCHHHHHHHCCCC
DYVPLFEMVGIDIAVSPREATVNEVLKLTMGKGIEALATIEGEKAEIIEYTASGQSKIVG
CCCCHHHHHCCEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCCEECC
KPLSKIKFPKGAIVTMVVHDDDVIIPRGEFIIREGDRVIIFALSSAVRSVEKLFK
CCHHHCCCCCCCEEEEEEECCCEEEECCCEEEECCCEEEEEEHHHHHHHHHHHHC
>Mature Secondary Structure
MYVFFSKDYLSKQEQSIWEQSFLRGNLMKAVVIGAGEVGYHIAKFLSLTHDVIVIENDED
CEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHCCCEEEEECCHH
ALRRADELDVQVVEGNGANADILASVLPDVDILVAVTGVDEVNIVACMTAKLILRAHPGW
HHHCCCCCCEEEEECCCCCHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHEECCCCC
KETKTIARVSNPDYIDVPVTSRAQVGVDIMICPELALASEVAEVLSNPSAIDAEMFAGGK
HHHHHEEECCCCCEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHCCCC
VQMMEFAIRPDNRLVGKRMQDIELEDCCIVSAIFRNNDIIIPHGDDFIKANDHMVVVGKP
EEEEEEEECCCCHHHHCHHCCCCCCHHHEEEHHHCCCCEEEECCCCEEECCCCEEEEECC
RAMADLENVFGNEGPHRNRILLIGCGIVGFYLAKIIDKDENADLKVIEYRKSRCIEVAEM
HHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHH
LENALILNGDGTDVNLLREENIEDMDVVIAVTDNDEKNLLCSLLAKQMGAKKVIARADRS
HCCEEEECCCCCCEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHCHHHHHHHCCCC
DYVPLFEMVGIDIAVSPREATVNEVLKLTMGKGIEALATIEGEKAEIIEYTASGQSKIVG
CCCCHHHHHCCEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCCEECC
KPLSKIKFPKGAIVTMVVHDDDVIIPRGEFIIREGDRVIIFALSSAVRSVEKLFK
CCHHHCCCCCCCEEEEEEECCCEEEECCCEEEECCCEEEEEEHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]