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The map label for this gene is gsiC [H]

Identifier: 21228560

GI number: 21228560

Start: 2932528

End: 2933511

Strand: Reverse

Name: gsiC [H]

Synonym: MM_2458

Alternate gene names: 21228560

Gene position: 2933511-2932528 (Counterclockwise)

Preceding gene: 21228561

Following gene: 21228559

Centisome position: 71.61

GC content: 45.22

Gene sequence:

>984_bases
ATGGAAAAGGACAGGAATTCGTTTATTTTCAGGTTATTATCGACCCTTTTTGTAATTCTTGCCATAAACTTTTTTCTTCC
AAGAATGATGCCAGGTGACCCTTTCGCAACCACTTCCGCGGATGAGGTAGGGGAAGAAATTATTGTAATGACAGAAGAGC
AGCGCCTTTATTACCTGAACTATTACGGGCTTGACAGACCCCTGTATGAACAGTTTTTAGTATATATAAAAAATCTGATG
ACTGGAAATCTGGGAAAGAGCATTTATTACAAAATGCCTGTCAGCGACGTAATACTGCTGCATCTCCCCTGGACCGTGCT
GATTGTCATGGGAGCGACTGTAATAAGTACAGTCTCAGGTGTGCTTCTCGGGACACTTTCGGCTAAAAACAGGAAAAATG
GAAGTGACAGGATTATGATGACAGGTATGATAGCTTTTGCAGAAATTCCCTCATTTCTGCTTGGCCTGATCCTTCTTCTT
ATTTTCAGTGTGCACCTAAGGCTTTTCCCACTTGCGGGTGCCATTACTCCCTTCGCAGATTATACTGGTCTGGCAGAACA
GGCATGGGACATACTGTATCATGCCTTCCTTCCTGTTGTGACCCTCTCCCTTTCCCAGCTGACCGGAGTTTACCTGCTAA
CCAGAAATACTCTGATTACAGTGACCACAAAGGACTACATCAGGACTGCGAGAGCCAAAGGCCTGGGAGAAAAAACCGTA
TGGACACGGCATGCTCTCAGGAACGCACTTCTTCCTGTGGTGACAAGGACAGGGTTTATGATCGGAATAATGATGGGCGG
TGTTGTGCTGGTTGAGAGTGTTTTTTCCTATCCCGGGATAGGGATGACACTCAGAAGTGCTGTAATCGGCAGGGATTATC
CTCTTATCCAGGGAATTCTGCTGGTAATTGCAGTCTCCATACTCGTCTGCAACCTGATGGTTGACAAAATATACGGGAAA
CTTGATCCGAGAGTTGTGGTATGA

Upstream 100 bases:

>100_bases
TCAGGATGGGATCTACCGTTCCAAATCCGATGTATATACCGGCATGATGGTCTGGGAAGTTAACGGCAAATGATCGGATA
ATGAAGGGGCAGATGATTGG

Downstream 100 bases:

>100_bases
TAAAGGATGTTGCTGCCTCTGGAAATGCCAGAATTATTTCATTTGCTCAGGCGTTAAATATTGACAAATTTGTAAGCGGT
ACAGCTGAAACATTTTCGAA

Product: peptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MEKDRNSFIFRLLSTLFVILAINFFLPRMMPGDPFATTSADEVGEEIIVMTEEQRLYYLNYYGLDRPLYEQFLVYIKNLM
TGNLGKSIYYKMPVSDVILLHLPWTVLIVMGATVISTVSGVLLGTLSAKNRKNGSDRIMMTGMIAFAEIPSFLLGLILLL
IFSVHLRLFPLAGAITPFADYTGLAEQAWDILYHAFLPVVTLSLSQLTGVYLLTRNTLITVTTKDYIRTARAKGLGEKTV
WTRHALRNALLPVVTRTGFMIGIMMGGVVLVESVFSYPGIGMTLRSAVIGRDYPLIQGILLVIAVSILVCNLMVDKIYGK
LDPRVVV

Sequences:

>Translated_327_residues
MEKDRNSFIFRLLSTLFVILAINFFLPRMMPGDPFATTSADEVGEEIIVMTEEQRLYYLNYYGLDRPLYEQFLVYIKNLM
TGNLGKSIYYKMPVSDVILLHLPWTVLIVMGATVISTVSGVLLGTLSAKNRKNGSDRIMMTGMIAFAEIPSFLLGLILLL
IFSVHLRLFPLAGAITPFADYTGLAEQAWDILYHAFLPVVTLSLSQLTGVYLLTRNTLITVTTKDYIRTARAKGLGEKTV
WTRHALRNALLPVVTRTGFMIGIMMGGVVLVESVFSYPGIGMTLRSAVIGRDYPLIQGILLVIAVSILVCNLMVDKIYGK
LDPRVVV
>Mature_327_residues
MEKDRNSFIFRLLSTLFVILAINFFLPRMMPGDPFATTSADEVGEEIIVMTEEQRLYYLNYYGLDRPLYEQFLVYIKNLM
TGNLGKSIYYKMPVSDVILLHLPWTVLIVMGATVISTVSGVLLGTLSAKNRKNGSDRIMMTGMIAFAEIPSFLLGLILLL
IFSVHLRLFPLAGAITPFADYTGLAEQAWDILYHAFLPVVTLSLSQLTGVYLLTRNTLITVTTKDYIRTARAKGLGEKTV
WTRHALRNALLPVVTRTGFMIGIMMGGVVLVESVFSYPGIGMTLRSAVIGRDYPLIQGILLVIAVSILVCNLMVDKIYGK
LDPRVVV

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=314, Percent_Identity=34.3949044585987, Blast_Score=194, Evalue=7e-51,
Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=33.6283185840708, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1789888, Length=306, Percent_Identity=33.0065359477124, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787497, Length=315, Percent_Identity=30.7936507936508, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1787761, Length=321, Percent_Identity=31.4641744548287, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788504, Length=350, Percent_Identity=27.4285714285714, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787550, Length=288, Percent_Identity=26.7361111111111, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36431; Mature: 36431

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKDRNSFIFRLLSTLFVILAINFFLPRMMPGDPFATTSADEVGEEIIVMTEEQRLYYLN
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCEEEEEECCCEEEEEE
YYGLDRPLYEQFLVYIKNLMTGNLGKSIYYKMPVSDVILLHLPWTVLIVMGATVISTVSG
EECCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLGTLSAKNRKNGSDRIMMTGMIAFAEIPSFLLGLILLLIFSVHLRLFPLAGAITPFAD
HHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
YTGLAEQAWDILYHAFLPVVTLSLSQLTGVYLLTRNTLITVTTKDYIRTARAKGLGEKTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCEEEEEECHHHHHHHHHCCCCCHHH
WTRHALRNALLPVVTRTGFMIGIMMGGVVLVESVFSYPGIGMTLRSAVIGRDYPLIQGIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHH
LVIAVSILVCNLMVDKIYGKLDPRVVV
HHHHHHHHHHHHHHHHHHCCCCCEEEC
>Mature Secondary Structure
MEKDRNSFIFRLLSTLFVILAINFFLPRMMPGDPFATTSADEVGEEIIVMTEEQRLYYLN
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCEEEEEECCCEEEEEE
YYGLDRPLYEQFLVYIKNLMTGNLGKSIYYKMPVSDVILLHLPWTVLIVMGATVISTVSG
EECCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLGTLSAKNRKNGSDRIMMTGMIAFAEIPSFLLGLILLLIFSVHLRLFPLAGAITPFAD
HHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
YTGLAEQAWDILYHAFLPVVTLSLSQLTGVYLLTRNTLITVTTKDYIRTARAKGLGEKTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCEEEEEECHHHHHHHHHCCCCCHHH
WTRHALRNALLPVVTRTGFMIGIMMGGVVLVESVFSYPGIGMTLRSAVIGRDYPLIQGIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHH
LVIAVSILVCNLMVDKIYGKLDPRVVV
HHHHHHHHHHHHHHHHHHCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]