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The map label for this gene is sod [H]

Identifier: 21228525

GI number: 21228525

Start: 2891414

End: 2892046

Strand: Direct

Name: sod [H]

Synonym: MM_2423

Alternate gene names: 21228525

Gene position: 2891414-2892046 (Clockwise)

Preceding gene: 21228523

Following gene: 21228529

Centisome position: 70.59

GC content: 43.13

Gene sequence:

>633_bases
TTGAATAACATGGCTAAAGAGTTATACAAATTACCACCGTTAAAATACGGATATGCAGACCTCGAACCTTACATTTCCGA
AGAACAGCTGCGCATACACCATGACAAGCACCATCAGGGTTATGTGAACAACACCAACTCACTGATGGAAATGATGGACA
AAGCCAGGAAAGACGGAACAGACTTTGATTATAAGGCAACTGCAAAAGCTCTGGCTTTTAATCTGGGAGGGCATGTCCTT
CATGACTATTTCTGGTGGGAGATGACTCCTGCAAGCAATGCCAGCAAAGAGCCTGTCGGCGACCTGGCTGACGTTATCAA
AGAGGATTTCGGAAGCTTTGAAAGGTTTAAAAAAGAATTTACCCAGATTGCGTCAGGCGTGGAAGGTTCGGGCTGGGCAG
CAGTAACATACTGCAACGACACCAAAAGGCTCGGGATAATGCAGATAGAAAAGCACAACGTGAACGTAGTCCCTGATTAT
CCGATCCTTATGGTTCTGGACGTATGGGAACATGCTTACTATATTGACTACAAGAATGATAGGGGCAAATTCATAGAAGG
GTTCTGGAATATAATTAACTGGGAAGAAATCGACAGGTATTTCAAGAAACTTCAAAGCATGAAAATGGAATAA

Upstream 100 bases:

>100_bases
TGGAAATAAAGGCAACAATGCATATACGCCTGGAGTACGGATACAGCCCTGCAGAGGTTCCCTATCACATTTTGCAAGCC
AGTTGATATTTTAAAGAGGG

Downstream 100 bases:

>100_bases
TTCCATATCCTCAATAAAATAGTACGGCTGCAGTACCGGGAACTTCCCTGACAGGTTAACCAGGGAAATATTTTTTATTT
CATTGCCAGCGAGGCGTTGA

Product: superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MNNMAKELYKLPPLKYGYADLEPYISEEQLRIHHDKHHQGYVNNTNSLMEMMDKARKDGTDFDYKATAKALAFNLGGHVL
HDYFWWEMTPASNASKEPVGDLADVIKEDFGSFERFKKEFTQIASGVEGSGWAAVTYCNDTKRLGIMQIEKHNVNVVPDY
PILMVLDVWEHAYYIDYKNDRGKFIEGFWNIINWEEIDRYFKKLQSMKME

Sequences:

>Translated_210_residues
MNNMAKELYKLPPLKYGYADLEPYISEEQLRIHHDKHHQGYVNNTNSLMEMMDKARKDGTDFDYKATAKALAFNLGGHVL
HDYFWWEMTPASNASKEPVGDLADVIKEDFGSFERFKKEFTQIASGVEGSGWAAVTYCNDTKRLGIMQIEKHNVNVVPDY
PILMVLDVWEHAYYIDYKNDRGKFIEGFWNIINWEEIDRYFKKLQSMKME
>Mature_210_residues
MNNMAKELYKLPPLKYGYADLEPYISEEQLRIHHDKHHQGYVNNTNSLMEMMDKARKDGTDFDYKATAKALAFNLGGHVL
HDYFWWEMTPASNASKEPVGDLADVIKEDFGSFERFKKEFTQIASGVEGSGWAAVTYCNDTKRLGIMQIEKHNVNVVPDY
PILMVLDVWEHAYYIDYKNDRGKFIEGFWNIINWEEIDRYFKKLQSMKME

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=203, Percent_Identity=38.9162561576355, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI67782305, Length=203, Percent_Identity=38.9162561576355, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI67782309, Length=203, Percent_Identity=31.0344827586207, Blast_Score=110, Evalue=6e-25,
Organism=Escherichia coli, GI1787946, Length=197, Percent_Identity=37.5634517766497, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1790342, Length=210, Percent_Identity=35.7142857142857, Blast_Score=129, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17506561, Length=202, Percent_Identity=39.1089108910891, Blast_Score=150, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17569479, Length=195, Percent_Identity=41.025641025641, Blast_Score=150, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6321796, Length=200, Percent_Identity=35.5, Blast_Score=127, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17136812, Length=204, Percent_Identity=36.2745098039216, Blast_Score=148, Evalue=3e-36,

Paralogues:

None

Copy number: 2020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 900 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 24627; Mature: 24627

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNMAKELYKLPPLKYGYADLEPYISEEQLRIHHDKHHQGYVNNTNSLMEMMDKARKDGT
CCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHEECCCCCCCCCCCHHHHHHHHHHHHCCCC
DFDYKATAKALAFNLGGHVLHDYFWWEMTPASNASKEPVGDLADVIKEDFGSFERFKKEF
CCCHHHHHHHHHHHCCCHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TQIASGVEGSGWAAVTYCNDTKRLGIMQIEKHNVNVVPDYPILMVLDVWEHAYYIDYKND
HHHHCCCCCCCEEEEEEECCCCCCCEEEEECCCCEECCCCCHHHHEEHHHCEEEEEEECC
RGKFIEGFWNIINWEEIDRYFKKLQSMKME
CCHHHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNMAKELYKLPPLKYGYADLEPYISEEQLRIHHDKHHQGYVNNTNSLMEMMDKARKDGT
CCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHEECCCCCCCCCCCHHHHHHHHHHHHCCCC
DFDYKATAKALAFNLGGHVLHDYFWWEMTPASNASKEPVGDLADVIKEDFGSFERFKKEF
CCCHHHHHHHHHHHCCCHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TQIASGVEGSGWAAVTYCNDTKRLGIMQIEKHNVNVVPDYPILMVLDVWEHAYYIDYKND
HHHHCCCCCCCEEEEEEECCCCCCCEEEEECCCCEECCCCCHHHHEEHHHCEEEEEEECC
RGKFIEGFWNIINWEEIDRYFKKLQSMKME
CCHHHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2122808; 9371463; 1907270; 11197024 [H]