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The map label for this gene is yfdZ [C]

Identifier: 21228470

GI number: 21228470

Start: 2824002

End: 2825201

Strand: Direct

Name: yfdZ [C]

Synonym: MM_2368

Alternate gene names: 21228470

Gene position: 2824002-2825201 (Clockwise)

Preceding gene: 21228469

Following gene: 21228471

Centisome position: 68.94

GC content: 45.58

Gene sequence:

>1200_bases
TTGGAGAAAGCAGAATTCAGAGTAAGCAGAATTCAGAGTAAGCAGAATTCAGAGGATATTATTTACGGGACCTTAGGAGG
GCACAATTTGAAGGAAATCAAATTTTCAGAAAACGTATCCCGGATAGATACATCCGGGATCAGAAAGATTTTCGAAGCTG
CAGGTTCAAACGCGATCAATCTCGGGCTGGGGCAGCCTGATTTTGATACTCCAGACCATATAAAAGCCGCAGCAATTAAA
GCCATAAATGAAGGTTTTACCGGTTATACCGCAGGTCCCGGAATCCCTGAACTGAGGGAAGCCCTGAGCCAGAAATTCAA
GGAAGAAAACTGCTTTTCGGTCTCTCCTCAGGAAATAATAGTAACATCAGGAGCATCTGAAGCCCTTACAATTGCCCTCA
CAGCCCTTCTTAACCGGGGAGATGAAGTCCTTATTTCAAATCCCGGCTTTGTATCCTATAATGCCCTGACTGAAATGCTA
TACGGAAAGGTCGTAAATGTCCCTCTCGGGGAAGACCTTACAATGAAGCCTGAAGACGTGCTTGAAAGAATCACACCGAA
AACAAAAGCTATCATTCTTAACTCCCCATCCAATCCCACAGGCGCTGTTTCAAGCAGGGCAGATATCAAAGCCCTTGCCG
AGATCGCAGACGACCACAGGATAACCATAATTTCTGACGAGGTCTACGAGTATTTCATTTATGAAGGTGAACACGTAAGT
CCTGCCAGCTATTCGGACAATGTGGTCACCGTAAATGCTACTTCAAAAAGCTATGCTATGACAGGCTGGAGACTCGGATA
TCTGGCAGCTAGGAATGAATACATATCCCAGATGCTTAAAGTTCACCAGTATATTCAGGCGTGTGCAAACTCTATTGCCC
AGAAAGCAGCTTATGCCGCAGTAACCGGGCCAAAAGACTCTGTCAGTGCCATGCGTGAAGAGTTCAGAAAACGCAGGGAT
GTGCTTGTTAAAGGGCTTAATGACCTGGGTATGGAATGTGCTCTTCCAAAAGGAGCTTTTTACGCCTTCCCCAGAGTCTC
AAATTCCGCTGAGGTCGCCTCAAAAATGATCTCAAACGGCGTTGTCGTGGTCCCGGGAACAGCTTTCGGGAGTGAAGGAG
ACGGCTACATAAGAATTTCTTACGCGGCTTCAATGAAAGATATTGAAAAATCTCTGAGCATCATGGAAAAAGTGCTCTGA

Upstream 100 bases:

>100_bases
GGTGTTTCGGAAGCAGAACTCAAGTTGAGGCACACAAATATCGAATAACTGGCCAGAATCAAATACAGGTTTTAAATTTC
CGCAAAGCAGGCTGCCAAGT

Downstream 100 bases:

>100_bases
GTCTGTTTAAAAGAGAGTTTTTCTCTCCCTTTTTCACCTTTATTTTACCTTTTTTCTTTTTTGTTATCTTTTCTTTCTTT
TACATTTTGTTTTTTCTGAT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MEKAEFRVSRIQSKQNSEDIIYGTLGGHNLKEIKFSENVSRIDTSGIRKIFEAAGSNAINLGLGQPDFDTPDHIKAAAIK
AINEGFTGYTAGPGIPELREALSQKFKEENCFSVSPQEIIVTSGASEALTIALTALLNRGDEVLISNPGFVSYNALTEML
YGKVVNVPLGEDLTMKPEDVLERITPKTKAIILNSPSNPTGAVSSRADIKALAEIADDHRITIISDEVYEYFIYEGEHVS
PASYSDNVVTVNATSKSYAMTGWRLGYLAARNEYISQMLKVHQYIQACANSIAQKAAYAAVTGPKDSVSAMREEFRKRRD
VLVKGLNDLGMECALPKGAFYAFPRVSNSAEVASKMISNGVVVVPGTAFGSEGDGYIRISYAASMKDIEKSLSIMEKVL

Sequences:

>Translated_399_residues
MEKAEFRVSRIQSKQNSEDIIYGTLGGHNLKEIKFSENVSRIDTSGIRKIFEAAGSNAINLGLGQPDFDTPDHIKAAAIK
AINEGFTGYTAGPGIPELREALSQKFKEENCFSVSPQEIIVTSGASEALTIALTALLNRGDEVLISNPGFVSYNALTEML
YGKVVNVPLGEDLTMKPEDVLERITPKTKAIILNSPSNPTGAVSSRADIKALAEIADDHRITIISDEVYEYFIYEGEHVS
PASYSDNVVTVNATSKSYAMTGWRLGYLAARNEYISQMLKVHQYIQACANSIAQKAAYAAVTGPKDSVSAMREEFRKRRD
VLVKGLNDLGMECALPKGAFYAFPRVSNSAEVASKMISNGVVVVPGTAFGSEGDGYIRISYAASMKDIEKSLSIMEKVL
>Mature_399_residues
MEKAEFRVSRIQSKQNSEDIIYGTLGGHNLKEIKFSENVSRIDTSGIRKIFEAAGSNAINLGLGQPDFDTPDHIKAAAIK
AINEGFTGYTAGPGIPELREALSQKFKEENCFSVSPQEIIVTSGASEALTIALTALLNRGDEVLISNPGFVSYNALTEML
YGKVVNVPLGEDLTMKPEDVLERITPKTKAIILNSPSNPTGAVSSRADIKALAEIADDHRITIISDEVYEYFIYEGEHVS
PASYSDNVVTVNATSKSYAMTGWRLGYLAARNEYISQMLKVHQYIQACANSIAQKAAYAAVTGPKDSVSAMREEFRKRRD
VLVKGLNDLGMECALPKGAFYAFPRVSNSAEVASKMISNGVVVVPGTAFGSEGDGYIRISYAASMKDIEKSLSIMEKVL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=323, Percent_Identity=30.6501547987616, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI56713256, Length=323, Percent_Identity=30.6501547987616, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI95147551, Length=397, Percent_Identity=27.9596977329975, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI169881279, Length=397, Percent_Identity=27.9596977329975, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI169881281, Length=326, Percent_Identity=25.7668711656442, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI4507369, Length=349, Percent_Identity=24.6418338108883, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI215599424, Length=370, Percent_Identity=25.9459459459459, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI19263340, Length=370, Percent_Identity=25.9459459459459, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI4885351, Length=380, Percent_Identity=24.2105263157895, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1788722, Length=354, Percent_Identity=29.9435028248588, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1788627, Length=377, Percent_Identity=30.2387267904509, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1786816, Length=346, Percent_Identity=30.635838150289, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1787710, Length=307, Percent_Identity=22.8013029315961, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788332, Length=256, Percent_Identity=23.4375, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=399, Percent_Identity=25.5639097744361, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71994476, Length=399, Percent_Identity=25.5639097744361, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17567663, Length=379, Percent_Identity=27.9683377308707, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17567369, Length=317, Percent_Identity=24.9211356466877, Blast_Score=106, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6322401, Length=322, Percent_Identity=31.9875776397516, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6320317, Length=353, Percent_Identity=26.3456090651558, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323118, Length=375, Percent_Identity=27.2, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28573069, Length=390, Percent_Identity=27.4358974358974, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24646114, Length=390, Percent_Identity=27.4358974358974, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI28573067, Length=390, Percent_Identity=27.4358974358974, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI28573065, Length=390, Percent_Identity=27.4358974358974, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI18859735, Length=362, Percent_Identity=25.9668508287293, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI45551451, Length=399, Percent_Identity=22.5563909774436, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641770, Length=399, Percent_Identity=22.5563909774436, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641760, Length=399, Percent_Identity=22.5563909774436, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641768, Length=399, Percent_Identity=22.5563909774436, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641766, Length=399, Percent_Identity=22.5563909774436, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641764, Length=399, Percent_Identity=22.5563909774436, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43307; Mature: 43307

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKAEFRVSRIQSKQNSEDIIYGTLGGHNLKEIKFSENVSRIDTSGIRKIFEAAGSNAIN
CCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEE
LGLGQPDFDTPDHIKAAAIKAINEGFTGYTAGPGIPELREALSQKFKEENCFSVSPQEII
ECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEE
VTSGASEALTIALTALLNRGDEVLISNPGFVSYNALTEMLYGKVVNVPLGEDLTMKPEDV
EECCCCHHHHHHHHHHHCCCCEEEEECCCEEEHHHHHHHHHHHEECCCCCCCCCCCHHHH
LERITPKTKAIILNSPSNPTGAVSSRADIKALAEIADDHRITIISDEVYEYFIYEGEHVS
HHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEHHHEEEEEECCCCCC
PASYSDNVVTVNATSKSYAMTGWRLGYLAARNEYISQMLKVHQYIQACANSIAQKAAYAA
CCCCCCCEEEEEECCCCEEECCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
VTGPKDSVSAMREEFRKRRDVLVKGLNDLGMECALPKGAFYAFPRVSNSAEVASKMISNG
ECCCHHHHHHHHHHHHHHHHHHHHCHHHCCCEECCCCCCEEECCCCCCHHHHHHHHHHCC
VVVVPGTAFGSEGDGYIRISYAASMKDIEKSLSIMEKVL
EEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MEKAEFRVSRIQSKQNSEDIIYGTLGGHNLKEIKFSENVSRIDTSGIRKIFEAAGSNAIN
CCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEE
LGLGQPDFDTPDHIKAAAIKAINEGFTGYTAGPGIPELREALSQKFKEENCFSVSPQEII
ECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEE
VTSGASEALTIALTALLNRGDEVLISNPGFVSYNALTEMLYGKVVNVPLGEDLTMKPEDV
EECCCCHHHHHHHHHHHCCCCEEEEECCCEEEHHHHHHHHHHHEECCCCCCCCCCCHHHH
LERITPKTKAIILNSPSNPTGAVSSRADIKALAEIADDHRITIISDEVYEYFIYEGEHVS
HHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEHHHEEEEEECCCCCC
PASYSDNVVTVNATSKSYAMTGWRLGYLAARNEYISQMLKVHQYIQACANSIAQKAAYAA
CCCCCCCEEEEEECCCCEEECCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
VTGPKDSVSAMREEFRKRRDVLVKGLNDLGMECALPKGAFYAFPRVSNSAEVASKMISNG
ECCCHHHHHHHHHHHHHHHHHHHHCHHHCCCEECCCCCCEEECCCCCCHHHHHHHHHHCC
VVVVPGTAFGSEGDGYIRISYAASMKDIEKSLSIMEKVL
EEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]