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The map label for this gene is ubiE [C]

Identifier: 21228434

GI number: 21228434

Start: 2790987

End: 2791670

Strand: Direct

Name: ubiE [C]

Synonym: MM_2332

Alternate gene names: 21228434

Gene position: 2790987-2791670 (Clockwise)

Preceding gene: 21228432

Following gene: 21228436

Centisome position: 68.13

GC content: 42.84

Gene sequence:

>684_bases
ATGCCTGAATCATACTGGGAAAAGGTATCCGGGAAGAACATACCTTCAAGCCTTGATCTTTACCCTATAATTCACAACTA
CCTGCAGGAAGATGATGAAATTCTTGATATCGGATGTGGGTCTGGAAAAATCAGTCTTGAGCTTGCTTCCCTGGGGTATT
CGGTAACAGGAATTGATATAAATTCTGAAGCGATCAGGCTTGCAGAAACTGCTGCAAGAAGCCCTGGTCTGAATCAAAAG
ACTGGAGGGAAGGCTGAGTTTAAGGTTGAAAATGCTTCTTCTCTTTCTTTTCATGACTCAAGTTTTGATTTTGCAGTCAT
GCAGGCATTTTTGACCTCTGTGCCGGACCCTAAGGAAAGATCCAGGATAATTAAAGAAGTTTTTCGAGTCCTGAAACCCG
GAGCTTATCTGTACCTTGTGGAATTCGGCCAGAACTGGCACCTGAAGCTCTACAGGAAACGATACCTCCACGACTTCCCA
ATTACAAAAGAAGAAGGGTCTTTCCTTGCCCGTGACCCTGAAACAGGGGAGACTGAGTTTATTGCACACCATTTTACTGA
AAAAGAGCTTGTGTTCCTGCTCACAGATTGCAGATTTGAAATTGATTATTTCAGGGTCAAAGAACTGGAGACGAGGACAG
GGAACAAAATTCTGGGGTTTGTAATTATTGCTCAGAAACTTTAA

Upstream 100 bases:

>100_bases
TCCTGCAGTTCTTTTAGCTTCTATTTTCTATTTTACTCGAAAACTCGTGAAGTCCGGAATTGCGAAATGTTCTTTATTCT
TCACCTGCATCTGATTCTTT

Downstream 100 bases:

>100_bases
ATTTCAGGCAGCAGACAATTTTGTCAGGAGCTGAAGGGCTTCAAACCTGATATTTTTGAAGCTCGATCTTATCTTTTAAG
ATTTTACTCAGTACGGAACT

Product: SAM-dependent methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: SAM-Dependent Methyltransferase; UbiE/COQ5 Methyltransferase

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MPESYWEKVSGKNIPSSLDLYPIIHNYLQEDDEILDIGCGSGKISLELASLGYSVTGIDINSEAIRLAETAARSPGLNQK
TGGKAEFKVENASSLSFHDSSFDFAVMQAFLTSVPDPKERSRIIKEVFRVLKPGAYLYLVEFGQNWHLKLYRKRYLHDFP
ITKEEGSFLARDPETGETEFIAHHFTEKELVFLLTDCRFEIDYFRVKELETRTGNKILGFVIIAQKL

Sequences:

>Translated_227_residues
MPESYWEKVSGKNIPSSLDLYPIIHNYLQEDDEILDIGCGSGKISLELASLGYSVTGIDINSEAIRLAETAARSPGLNQK
TGGKAEFKVENASSLSFHDSSFDFAVMQAFLTSVPDPKERSRIIKEVFRVLKPGAYLYLVEFGQNWHLKLYRKRYLHDFP
ITKEEGSFLARDPETGETEFIAHHFTEKELVFLLTDCRFEIDYFRVKELETRTGNKILGFVIIAQKL
>Mature_226_residues
PESYWEKVSGKNIPSSLDLYPIIHNYLQEDDEILDIGCGSGKISLELASLGYSVTGIDINSEAIRLAETAARSPGLNQKT
GGKAEFKVENASSLSFHDSSFDFAVMQAFLTSVPDPKERSRIIKEVFRVLKPGAYLYLVEFGQNWHLKLYRKRYLHDFPI
TKEEGSFLARDPETGETEFIAHHFTEKELVFLLTDCRFEIDYFRVKELETRTGNKILGFVIIAQKL

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI48994983, Length=179, Percent_Identity=26.2569832402235, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 25852; Mature: 25720

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS01184 UBIE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPESYWEKVSGKNIPSSLDLYPIIHNYLQEDDEILDIGCGSGKISLELASLGYSVTGIDI
CCHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCEEEEEEEECCEEEEEEEC
NSEAIRLAETAARSPGLNQKTGGKAEFKVENASSLSFHDSSFDFAVMQAFLTSVPDPKER
CHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEECCCCCCHHHHHHHHHCCCCHHHH
SRIIKEVFRVLKPGAYLYLVEFGQNWHLKLYRKRYLHDFPITKEEGSFLARDPETGETEF
HHHHHHHHHHHCCCCEEEEEEECCCCEEEHHHHHHHHCCCCCCCCCCEEECCCCCCCHHH
IAHHFTEKELVFLLTDCRFEIDYFRVKELETRTGNKILGFVIIAQKL
HHHHCCCCEEEEEEECCEEEEEEEEEEEHHCCCCCEEEEEEEEEECC
>Mature Secondary Structure 
PESYWEKVSGKNIPSSLDLYPIIHNYLQEDDEILDIGCGSGKISLELASLGYSVTGIDI
CHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCEEEEEEEECCEEEEEEEC
NSEAIRLAETAARSPGLNQKTGGKAEFKVENASSLSFHDSSFDFAVMQAFLTSVPDPKER
CHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEECCCCCCHHHHHHHHHCCCCHHHH
SRIIKEVFRVLKPGAYLYLVEFGQNWHLKLYRKRYLHDFPITKEEGSFLARDPETGETEF
HHHHHHHHHHHCCCCEEEEEEECCCCEEEHHHHHHHHCCCCCCCCCCEEECCCCCCCHHH
IAHHFTEKELVFLLTDCRFEIDYFRVKELETRTGNKILGFVIIAQKL
HHHHCCCCEEEEEEECCEEEEEEEEEEEHHCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA