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The map label for this gene is prf1 [H]

Identifier: 21228388

GI number: 21228388

Start: 2725064

End: 2725960

Strand: Direct

Name: prf1 [H]

Synonym: MM_2286

Alternate gene names: 21228388

Gene position: 2725064-2725960 (Clockwise)

Preceding gene: 21228356

Following gene: 21228389

Centisome position: 66.52

GC content: 47.6

Gene sequence:

>897_bases
TTGCAGAATACAAAAAACCAGCTTGAAAAGAAAGAAGCACTTGCAAGACAGGCAGTTGCAGACAGACAGGAAGCTGAATC
CCGCTTGAACCAGGAACGTGTAAGGACTCAGACCCTTTCGCATGAACTTGATAAAATGCGTACTGAATCACAGAACAGGC
TCGAGTTCCGCGGGGTTGAAAACCTGAGCCCTTCTGCCGTTCAGGCTTACCTTTCAAAACTCAGTTCTTTCCGTTCCCCT
TCTGAGGATCTATTAACTGTATATCTGCCCGCCGGAACTCGCCTTTTAGCTATAGTTCCTGAAAAAACTCTTGAGCTGGT
CGAAGAAGAAACCTGCTCTCTTCTTGACAGGCTCAACACCGAAACAGGCATGATCTTTTTTTACGACCTGCACCGCATGA
TCTCAGAAGCCATAGTCCCTCCTTTCCCTGTCTCCTCTGCTGTCTGGTACCTCAAGGACAGCTTTGAGACCGCTCCGCTT
GAGGAAAACCTGAATTCCTCCTGCCGCATGCTTGTACTTGTCCTGCATGCAGGCGAGTCTTTCATAGGCTTTGCTCCTGA
TGCCCGTGTTTTTGATACGGAGGAATTCATCAAAAGCAGCGTCAAAGAAAAACACAGCAAAGGGGGTTTCTCCCAGCGCC
GTTTCGAACGCCTCAGGGAAGAGGATATTGCCCACCACATGGACAAAGTCTTTGAGGCTCTGGACAAAATACTCGAAGAA
AATTCCCCTGTAGATTTCGTTATTTTGAACGGGGATACTCCACTTATAAGGGAAGCTGAGAAGCGCCTGCCTCTGAGCCC
TGAGATTATTGAGAAGCCGGCTGATATTAAGGTTGAAAAAACGGGTGGAGAGGAGATTTTAAGGACGGTTTTAAGCTCAA
GAAGGTATCTGCTATGA

Upstream 100 bases:

>100_bases
AAAAGGTCTGGGCACCATTATAGGAAAAATCTCCGGAAAGGGCAGGCTGGAAACGGAGGTTGAGAGGCTTGCTTCAAGAG
TAGACGAGCTCGAACTGGGC

Downstream 100 bases:

>100_bases
AACTGGGAGATATTTGCTGTAAAGTGCTGAAAAATTTGCTGTAGATTCTGAAAAACATATGTAAAGAGCCGAAAAATATG
GACGCAAAGAAGTTCACATC

Product: hypothetical protein

Products: NA

Alternate protein names: Translation termination factor aRF1 [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MQNTKNQLEKKEALARQAVADRQEAESRLNQERVRTQTLSHELDKMRTESQNRLEFRGVENLSPSAVQAYLSKLSSFRSP
SEDLLTVYLPAGTRLLAIVPEKTLELVEEETCSLLDRLNTETGMIFFYDLHRMISEAIVPPFPVSSAVWYLKDSFETAPL
EENLNSSCRMLVLVLHAGESFIGFAPDARVFDTEEFIKSSVKEKHSKGGFSQRRFERLREEDIAHHMDKVFEALDKILEE
NSPVDFVILNGDTPLIREAEKRLPLSPEIIEKPADIKVEKTGGEEILRTVLSSRRYLL

Sequences:

>Translated_298_residues
MQNTKNQLEKKEALARQAVADRQEAESRLNQERVRTQTLSHELDKMRTESQNRLEFRGVENLSPSAVQAYLSKLSSFRSP
SEDLLTVYLPAGTRLLAIVPEKTLELVEEETCSLLDRLNTETGMIFFYDLHRMISEAIVPPFPVSSAVWYLKDSFETAPL
EENLNSSCRMLVLVLHAGESFIGFAPDARVFDTEEFIKSSVKEKHSKGGFSQRRFERLREEDIAHHMDKVFEALDKILEE
NSPVDFVILNGDTPLIREAEKRLPLSPEIIEKPADIKVEKTGGEEILRTVLSSRRYLL
>Mature_298_residues
MQNTKNQLEKKEALARQAVADRQEAESRLNQERVRTQTLSHELDKMRTESQNRLEFRGVENLSPSAVQAYLSKLSSFRSP
SEDLLTVYLPAGTRLLAIVPEKTLELVEEETCSLLDRLNTETGMIFFYDLHRMISEAIVPPFPVSSAVWYLKDSFETAPL
EENLNSSCRMLVLVLHAGESFIGFAPDARVFDTEEFIKSSVKEKHSKGGFSQRRFERLREEDIAHHMDKVFEALDKILEE
NSPVDFVILNGDTPLIREAEKRLPLSPEIIEKPADIKVEKTGGEEILRTVLSSRRYLL

Specific function: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA [H]

COG id: COG1503

COG function: function code J; Peptide chain release factor 1 (eRF1)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eukaryotic release factor 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005140
- InterPro:   IPR005141
- InterPro:   IPR005142
- InterPro:   IPR020918
- InterPro:   IPR004403 [H]

Pfam domain/function: PF03463 eRF1_1; PF03464 eRF1_2; PF03465 eRF1_3 [H]

EC number: NA

Molecular weight: Translated: 34067; Mature: 34067

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNTKNQLEKKEALARQAVADRQEAESRLNQERVRTQTLSHELDKMRTESQNRLEFRGVE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCC
NLSPSAVQAYLSKLSSFRSPSEDLLTVYLPAGTRLLAIVPEKTLELVEEETCSLLDRLNT
CCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHCCC
ETGMIFFYDLHRMISEAIVPPFPVSSAVWYLKDSFETAPLEENLNSSCRMLVLVLHAGES
CCCEEHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHCCCC
FIGFAPDARVFDTEEFIKSSVKEKHSKGGFSQRRFERLREEDIAHHMDKVFEALDKILEE
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NSPVDFVILNGDTPLIREAEKRLPLSPEIIEKPADIKVEKTGGEEILRTVLSSRRYLL
CCCEEEEEECCCCHHHHHHHHCCCCCHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQNTKNQLEKKEALARQAVADRQEAESRLNQERVRTQTLSHELDKMRTESQNRLEFRGVE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCC
NLSPSAVQAYLSKLSSFRSPSEDLLTVYLPAGTRLLAIVPEKTLELVEEETCSLLDRLNT
CCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHCCC
ETGMIFFYDLHRMISEAIVPPFPVSSAVWYLKDSFETAPLEENLNSSCRMLVLVLHAGES
CCCEEHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHCCCC
FIGFAPDARVFDTEEFIKSSVKEKHSKGGFSQRRFERLREEDIAHHMDKVFEALDKILEE
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NSPVDFVILNGDTPLIREAEKRLPLSPEIIEKPADIKVEKTGGEEILRTVLSSRRYLL
CCCEEEEEECCCCHHHHHHHHCCCCCHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]