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The map label for this gene is arsR [C]

Identifier: 21228348

GI number: 21228348

Start: 2673949

End: 2674389

Strand: Reverse

Name: arsR [C]

Synonym: MM_2246

Alternate gene names: 21228348

Gene position: 2674389-2673949 (Counterclockwise)

Preceding gene: 21228353

Following gene: 21228347

Centisome position: 65.29

GC content: 40.82

Gene sequence:

>441_bases
GTGGAGGCAGCTGCTGCAGGTAAATTCATGAAAGCTGAAAGAAAATCAGATGTGAACAAAAGAAAGCGTGAAGTGGAAAT
TGGAAGATTGGAACGTTTTATTTTTGACAGAGATCAGTTAGAGGTAAGAACGCAAAAGCTCAGTTCTCTGGTAAATGGGC
TGGATGAAGAAGCACTATACTCAGAAGCCAGGATTTTTAAAGCCCTTGCAGATCCCAATCGCCTCAAAATTGTAAAACTA
TTAAAAGAAGGAGAACTCTGTGCCTGCGAATTAACTATTGCACTTTCCAGTTCCCAATCGACTGTTTCTCACCATCTTTC
GGTATTGAAGAGTGCGGGCCTGGTCAAAGAACGGAAAGAAGGAAAATGGTCTTACTTTCGTCTCTCAGAAGGAGCAGTTA
TTGAAATACTTAACCAGGCAAAATTGCTTCATGAAAGATGA

Upstream 100 bases:

>100_bases
TCGTTACTCAGAGCCAATCACAGGGACTTAGGAAATATAAAGATGTGTGTGAAGTGCTGATCAAAAGAACAGTGTAAAAA
CATGCTACTTCCTATAGGAA

Downstream 100 bases:

>100_bases
GATTTCAGAAAGTTATATTTTTAAAAGTAGCATTAAGGGCCGGATCTGTATCCCTTAAAAATGGTTAAAGCTTCAGAAAA
ATCGCATTTATGAGAGGGTG

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MEAAAAGKFMKAERKSDVNKRKREVEIGRLERFIFDRDQLEVRTQKLSSLVNGLDEEALYSEARIFKALADPNRLKIVKL
LKEGELCACELTIALSSSQSTVSHHLSVLKSAGLVKERKEGKWSYFRLSEGAVIEILNQAKLLHER

Sequences:

>Translated_146_residues
MEAAAAGKFMKAERKSDVNKRKREVEIGRLERFIFDRDQLEVRTQKLSSLVNGLDEEALYSEARIFKALADPNRLKIVKL
LKEGELCACELTIALSSSQSTVSHHLSVLKSAGLVKERKEGKWSYFRLSEGAVIEILNQAKLLHER
>Mature_146_residues
MEAAAAGKFMKAERKSDVNKRKREVEIGRLERFIFDRDQLEVRTQKLSSLVNGLDEEALYSEARIFKALADPNRLKIVKL
LKEGELCACELTIALSSSQSTVSHHLSVLKSAGLVKERKEGKWSYFRLSEGAVIEILNQAKLLHER

Specific function: Transcriptional Repressor For The Arsefg Operon. Arse Is A Trans-Acting Regulatory Protein Which Controls Its Own Expression. The Repressive Effect Of Arse Is Alleviated By Oxyions Of +III Oxidation State Of Arsenic, Antimony, And Bismuth, As Well As Arse

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=68, Percent_Identity=52.9411764705882, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 16557; Mature: 16557

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAAAAGKFMKAERKSDVNKRKREVEIGRLERFIFDRDQLEVRTQKLSSLVNGLDEEALY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHH
SEARIFKALADPNRLKIVKLLKEGELCACELTIALSSSQSTVSHHLSVLKSAGLVKERKE
HHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCHHHHHCC
GKWSYFRLSEGAVIEILNQAKLLHER
CCCEEEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEAAAAGKFMKAERKSDVNKRKREVEIGRLERFIFDRDQLEVRTQKLSSLVNGLDEEALY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHH
SEARIFKALADPNRLKIVKLLKEGELCACELTIALSSSQSTVSHHLSVLKSAGLVKERKE
HHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEEEEECCCHHHHHHHHHHHHHCCHHHHHCC
GKWSYFRLSEGAVIEILNQAKLLHER
CCCEEEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]