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The map label for this gene is yleA [C]

Identifier: 21228284

GI number: 21228284

Start: 2588166

End: 2589473

Strand: Direct

Name: yleA [C]

Synonym: MM_2182

Alternate gene names: 21228284

Gene position: 2588166-2589473 (Clockwise)

Preceding gene: 21228283

Following gene: 21228287

Centisome position: 63.18

GC content: 47.32

Gene sequence:

>1308_bases
ATGAAGGTTTATCTTGAGAGTTTTGGCTGTTCTGCAAGTCAGGCATCAGCCGAGATAATGAAAGCGAGCATTGGGAAGCT
CGGGCATGAATTATTGAGCCCTGAAAATGCGGGGCAGGCAGAGGTCTATATCTGCAACTCCTGCACGGTGAAATACACAA
CAGAACAGAAAATTCTCTATAAAATACGCAGCATGGGCGAGAAAGGCGTACAGGTGATTGTTTCAGGCTGCATGCCCGAA
GTCCAGCTTGAAGATATCCTCCATGCAAACCCTGAAGCCCATATTCTTGGCGTGAATGCGGTTTCCCGCCTGGGGGACCT
TCTTTCCACAATCGAACAGAGAAAAAAGACTGGAATCCCCGGAGGAGAACGTCTGGAAATCCGGACCTCCGAGCCTCAGG
GTTTCCTGAATGTCCCTCGCGAGCGCTCAAATCCGAACATCCATATCTGCCAGATCTCCCAGGGCTGTAATTTCGCCTGC
TCTTATTGTATAGTAAAGCATGCAAGGGGTAAACTCCTCTCTTTTCCCCCTGAAGAAATAATAGAAGACATCCGCTCTGC
AGTTGCAGACGGCTGCAGGGAGATATGGCTCACGTCTCAGGACGACAGCCAGTACGGCATGGATACGGGCGTCAAACTCC
CTGAACTCCTGCGTGCGATCTCAGAAATTCCGGGTGATTTTAAGGTAAGGGTTGGCATGATGAACCCCTTCTCTGTCCTC
CCTATTCTGGACGATCTGGTGGATGCCTTTGATTCGGATAAGATTTTCAAACTTCTTCACCTCCCGATTCAGTCTGCCTC
GCATTCGGTCCTGAAAAAAATGAACCGCCTGCATAAAATGGATTCCGTGGATGAAATTATTACGAAATTCCGTGCCCACT
TTGAAGACCTTTCCCTCTTTACCGACATAATTGTCGGCTTCTGTGATGAAACCGATGAGGATTTTGAAGAAACCATAGAG
TGGGTAAAAAAATACCGTCCCGAAAAGATCAATATTTCCAGATATTCACCCCGCCCGCATACAAAGGCATTTTCGTTCAG
GAATCTGGACTCCAGAATTTCAGTAAAACGCTCTCACCAACTTCACAAAGTCTGTGAGCAGATAAAGATTGAATCCAAAA
ATGAAATGATTGGCTGGAAAGGCAGAGTTTTTGTCTCAAAATACACAGAGATCGGAGATGTTCTCACGCGTACGGACTCT
TACCGTCCGGTTGTGATTAGCGGCTCAGATCTCAGACCCGGCGAATATGCTGAAGTGAAAATTACGGGTGCAAAGCCCGG
TTACTTCCTTGGAAAACTTGTCAGCTAA

Upstream 100 bases:

>100_bases
GGGCTAATTGTTAATTTCATATCAGCTGTTAATTAAAGTGCTGTCCCGGTATCAACTAAATGTTAAGTTAAAACATCAGT
TCAAAATGTGAAGGCAGAAT

Downstream 100 bases:

>100_bases
ATATGGAGACTATCCCAAAACCTGTTTTATTCAAAATTATCAGAAGTTTTCAAGATCATTTCCCATGATTAGATATTCTA
TTGACTGTTCCAAATACGAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MKVYLESFGCSASQASAEIMKASIGKLGHELLSPENAGQAEVYICNSCTVKYTTEQKILYKIRSMGEKGVQVIVSGCMPE
VQLEDILHANPEAHILGVNAVSRLGDLLSTIEQRKKTGIPGGERLEIRTSEPQGFLNVPRERSNPNIHICQISQGCNFAC
SYCIVKHARGKLLSFPPEEIIEDIRSAVADGCREIWLTSQDDSQYGMDTGVKLPELLRAISEIPGDFKVRVGMMNPFSVL
PILDDLVDAFDSDKIFKLLHLPIQSASHSVLKKMNRLHKMDSVDEIITKFRAHFEDLSLFTDIIVGFCDETDEDFEETIE
WVKKYRPEKINISRYSPRPHTKAFSFRNLDSRISVKRSHQLHKVCEQIKIESKNEMIGWKGRVFVSKYTEIGDVLTRTDS
YRPVVISGSDLRPGEYAEVKITGAKPGYFLGKLVS

Sequences:

>Translated_435_residues
MKVYLESFGCSASQASAEIMKASIGKLGHELLSPENAGQAEVYICNSCTVKYTTEQKILYKIRSMGEKGVQVIVSGCMPE
VQLEDILHANPEAHILGVNAVSRLGDLLSTIEQRKKTGIPGGERLEIRTSEPQGFLNVPRERSNPNIHICQISQGCNFAC
SYCIVKHARGKLLSFPPEEIIEDIRSAVADGCREIWLTSQDDSQYGMDTGVKLPELLRAISEIPGDFKVRVGMMNPFSVL
PILDDLVDAFDSDKIFKLLHLPIQSASHSVLKKMNRLHKMDSVDEIITKFRAHFEDLSLFTDIIVGFCDETDEDFEETIE
WVKKYRPEKINISRYSPRPHTKAFSFRNLDSRISVKRSHQLHKVCEQIKIESKNEMIGWKGRVFVSKYTEIGDVLTRTDS
YRPVVISGSDLRPGEYAEVKITGAKPGYFLGKLVS
>Mature_435_residues
MKVYLESFGCSASQASAEIMKASIGKLGHELLSPENAGQAEVYICNSCTVKYTTEQKILYKIRSMGEKGVQVIVSGCMPE
VQLEDILHANPEAHILGVNAVSRLGDLLSTIEQRKKTGIPGGERLEIRTSEPQGFLNVPRERSNPNIHICQISQGCNFAC
SYCIVKHARGKLLSFPPEEIIEDIRSAVADGCREIWLTSQDDSQYGMDTGVKLPELLRAISEIPGDFKVRVGMMNPFSVL
PILDDLVDAFDSDKIFKLLHLPIQSASHSVLKKMNRLHKMDSVDEIITKFRAHFEDLSLFTDIIVGFCDETDEDFEETIE
WVKKYRPEKINISRYSPRPHTKAFSFRNLDSRISVKRSHQLHKVCEQIKIESKNEMIGWKGRVFVSKYTEIGDVLTRTDS
YRPVVISGSDLRPGEYAEVKITGAKPGYFLGKLVS

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=447, Percent_Identity=30.2013422818792, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI28872784, Length=486, Percent_Identity=24.4855967078189, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI28872782, Length=486, Percent_Identity=24.4855967078189, Blast_Score=128, Evalue=9e-30,
Organism=Escherichia coli, GI1786882, Length=456, Percent_Identity=26.7543859649123, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1787057, Length=444, Percent_Identity=25.4504504504505, Blast_Score=121, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71996771, Length=334, Percent_Identity=32.6347305389222, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17553146, Length=467, Percent_Identity=23.7687366167024, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI19922432, Length=448, Percent_Identity=31.9196428571429, Blast_Score=228, Evalue=6e-60,
Organism=Drosophila melanogaster, GI21356207, Length=434, Percent_Identity=24.4239631336406, Blast_Score=115, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006466
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 48906; Mature: 48906

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS50926 TRAM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVYLESFGCSASQASAEIMKASIGKLGHELLSPENAGQAEVYICNSCTVKYTTEQKILY
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEHHHHHHH
KIRSMGEKGVQVIVSGCMPEVQLEDILHANPEAHILGVNAVSRLGDLLSTIEQRKKTGIP
HHHHCCHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCC
GGERLEIRTSEPQGFLNVPRERSNPNIHICQISQGCNFACSYCIVKHARGKLLSFPPEEI
CCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHH
IEDIRSAVADGCREIWLTSQDDSQYGMDTGVKLPELLRAISEIPGDFKVRVGMMNPFSVL
HHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHH
PILDDLVDAFDSDKIFKLLHLPIQSASHSVLKKMNRLHKMDSVDEIITKFRAHFEDLSLF
HHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TDIIVGFCDETDEDFEETIEWVKKYRPEKINISRYSPRPHTKAFSFRNLDSRISVKRSHQ
HHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEECCCCCHHHHHHHHHH
LHKVCEQIKIESKNEMIGWKGRVFVSKYTEIGDVLTRTDSYRPVVISGSDLRPGEYAEVK
HHHHHHHHCCCCCCCEECCCCEEEEHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEE
ITGAKPGYFLGKLVS
EECCCCCHHHHHHCC
>Mature Secondary Structure
MKVYLESFGCSASQASAEIMKASIGKLGHELLSPENAGQAEVYICNSCTVKYTTEQKILY
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEHHHHHHH
KIRSMGEKGVQVIVSGCMPEVQLEDILHANPEAHILGVNAVSRLGDLLSTIEQRKKTGIP
HHHHCCHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCC
GGERLEIRTSEPQGFLNVPRERSNPNIHICQISQGCNFACSYCIVKHARGKLLSFPPEEI
CCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHH
IEDIRSAVADGCREIWLTSQDDSQYGMDTGVKLPELLRAISEIPGDFKVRVGMMNPFSVL
HHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHH
PILDDLVDAFDSDKIFKLLHLPIQSASHSVLKKMNRLHKMDSVDEIITKFRAHFEDLSLF
HHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TDIIVGFCDETDEDFEETIEWVKKYRPEKINISRYSPRPHTKAFSFRNLDSRISVKRSHQ
HHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEECCCCCHHHHHHHHHH
LHKVCEQIKIESKNEMIGWKGRVFVSKYTEIGDVLTRTDSYRPVVISGSDLRPGEYAEVK
HHHHHHHHCCCCCCCEECCCCEEEEHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEE
ITGAKPGYFLGKLVS
EECCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]