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The map label for this gene is pknB [H]

Identifier: 21228224

GI number: 21228224

Start: 2536074

End: 2537264

Strand: Direct

Name: pknB [H]

Synonym: MM_2122

Alternate gene names: 21228224

Gene position: 2536074-2537264 (Clockwise)

Preceding gene: 21228223

Following gene: 21228225

Centisome position: 61.91

GC content: 46.35

Gene sequence:

>1191_bases
GTGACCCTTAAAACAAATATTGCTCTGGAAGGGGAGGAACTGAGGTTCCAGATGCCAGAAGCCGATGATATTATCAGCCC
CGAAAACCTCAGCACAATAGAATTCTCTTTAAAGGCTGTTCCTGAAAAGCCGGATATTGCCTCGTGTAAAGAAGTCCCTG
GCCTTGTCGGGCTTTCAAAAGAAGAAGCAGAAAGCAAACTTCAGGAGGCAGGTTTTAAGGCAGGAGAAATTCTTGAAAAA
GAAAGCAGCACCTCCCAGGGCACGGTAATAGGCCAGCTCCCATCGGACGGCTCCCTAGCAGCACCGGGGGCAGCTGTGGA
TCTTATCATTTCGAAAATAATTTCATTAAAAGTGCCGGACTTCTCAGGTCTCAGTCTCGAAGCTGCAAAAGCTCTCATTG
AAAAATCGCGGCTCAGGCTTGAAGGGGTCAAAGAAAAACCTTCTGATAAAACCCCTGGCATAGTCCTTGCACAGAGCCTC
CCGCCAGGTTCTGAAGTCAGTGTTGACACTACAATTGTCCTGACGGTTTCAATAGCGGTTTTTAAAGTCCCGAACCTGCT
TGGACTTGAGCTTGAGAGCGCAAAACAGGTAATAGATAAATCCGGACTCCTACCTGGCAGTATCAAAGAACAGCTCGTTA
GTAGTGGGAAGCCGGGCATTGTCCTTGCACAGAGCCTTAAACCCGGGGCTGAAGTGGAAAAATATTCAAAAATTGATCTT
GTAGTTTCAGCAGGGAAAATAGGGTCAGTTATTGAAGCGCCTTTGAATACTTTTCCCGAAACTGCTGCTAAAAAACCTGT
AAATAAAATTTTATCCGAAACCGCATCAAAGCTGCAGCCTGAAACTACATTTAAAGTTTCAGGTGAAACTCCATCGACTG
CGCCTTTAGAAACTCAGGTGAAAATATCTGCAGAGCCTCAGGTCCGAACCCATGCCGAACCCTCGGTAAAACTGGTTCCT
GATATTATCGGAATGCCTCTTGAAAAGGCTATCTCCTTACTTGGGGCTCAGGAGATAAAAGCAGGAACAGTATCTGAAGC
TGTTTCTACAGCTGCTGCAGGAACGGTTATAAGCCAGAATCCGGGTGCAGGCTCTATGGTTAACATGTCTGTGCCTGTCA
ACCTCACAGTCTCAAAAAAGGCACCTGTAACCCAGCTGCGCAGCAATACAATTTCCAGGATTAAGCTTTGA

Upstream 100 bases:

>100_bases
TTCGAACCTTGTAAGCACTTTTGCGTCCTCACTTGCGGAAATGGATAAAGGACTGAAGAAAATCCAGTCAGGTCCAAAGT
ACCTTGTCAGCGGTATGAAC

Downstream 100 bases:

>100_bases
TCTGCAGGTTTTTCAATGCCATTTGAAACGTATCTTATAAAGGTTACAGATAATGCTACAGCCTTTCAGGTCCAGAAGCT
CCTTAAATTGGTTCTGGAAA

Product: putative serine/threonine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MTLKTNIALEGEELRFQMPEADDIISPENLSTIEFSLKAVPEKPDIASCKEVPGLVGLSKEEAESKLQEAGFKAGEILEK
ESSTSQGTVIGQLPSDGSLAAPGAAVDLIISKIISLKVPDFSGLSLEAAKALIEKSRLRLEGVKEKPSDKTPGIVLAQSL
PPGSEVSVDTTIVLTVSIAVFKVPNLLGLELESAKQVIDKSGLLPGSIKEQLVSSGKPGIVLAQSLKPGAEVEKYSKIDL
VVSAGKIGSVIEAPLNTFPETAAKKPVNKILSETASKLQPETTFKVSGETPSTAPLETQVKISAEPQVRTHAEPSVKLVP
DIIGMPLEKAISLLGAQEIKAGTVSEAVSTAAAGTVISQNPGAGSMVNMSVPVNLTVSKKAPVTQLRSNTISRIKL

Sequences:

>Translated_396_residues
MTLKTNIALEGEELRFQMPEADDIISPENLSTIEFSLKAVPEKPDIASCKEVPGLVGLSKEEAESKLQEAGFKAGEILEK
ESSTSQGTVIGQLPSDGSLAAPGAAVDLIISKIISLKVPDFSGLSLEAAKALIEKSRLRLEGVKEKPSDKTPGIVLAQSL
PPGSEVSVDTTIVLTVSIAVFKVPNLLGLELESAKQVIDKSGLLPGSIKEQLVSSGKPGIVLAQSLKPGAEVEKYSKIDL
VVSAGKIGSVIEAPLNTFPETAAKKPVNKILSETASKLQPETTFKVSGETPSTAPLETQVKISAEPQVRTHAEPSVKLVP
DIIGMPLEKAISLLGAQEIKAGTVSEAVSTAAAGTVISQNPGAGSMVNMSVPVNLTVSKKAPVTQLRSNTISRIKL
>Mature_395_residues
TLKTNIALEGEELRFQMPEADDIISPENLSTIEFSLKAVPEKPDIASCKEVPGLVGLSKEEAESKLQEAGFKAGEILEKE
SSTSQGTVIGQLPSDGSLAAPGAAVDLIISKIISLKVPDFSGLSLEAAKALIEKSRLRLEGVKEKPSDKTPGIVLAQSLP
PGSEVSVDTTIVLTVSIAVFKVPNLLGLELESAKQVIDKSGLLPGSIKEQLVSSGKPGIVLAQSLKPGAEVEKYSKIDLV
VSAGKIGSVIEAPLNTFPETAAKKPVNKILSETASKLQPETTFKVSGETPSTAPLETQVKISAEPQVRTHAEPSVKLVPD
IIGMPLEKAISLLGAQEIKAGTVSEAVSTAAAGTVISQNPGAGSMVNMSVPVNLTVSKKAPVTQLRSNTISRIKL

Specific function: Unknown

COG id: COG2815

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR005543
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR008271 [H]

Pfam domain/function: PF03793 PASTA; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 41329; Mature: 41198

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKTNIALEGEELRFQMPEADDIISPENLSTIEFSLKAVPEKPDIASCKEVPGLVGLSK
CEEECEEEECCHHHEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHCCCCCCCCH
EEAESKLQEAGFKAGEILEKESSTSQGTVIGQLPSDGSLAAPGAAVDLIISKIISLKVPD
HHHHHHHHHCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHEECCC
FSGLSLEAAKALIEKSRLRLEGVKEKPSDKTPGIVLAQSLPPGSEVSVDTTIVLTVSIAV
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCEECEEEEEEEEEEE
FKVPNLLGLELESAKQVIDKSGLLPGSIKEQLVSSGKPGIVLAQSLKPGAEVEKYSKIDL
HHCCCHHCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCHHHHCEEEE
VVSAGKIGSVIEAPLNTFPETAAKKPVNKILSETASKLQPETTFKVSGETPSTAPLETQV
EEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEE
KISAEPQVRTHAEPSVKLVPDIIGMPLEKAISLLGAQEIKAGTVSEAVSTAAAGTVISQN
EEECCCCEECCCCCCCEECHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEECC
PGAGSMVNMSVPVNLTVSKKAPVTQLRSNTISRIKL
CCCCCEEEEEEEEEEEECCCCCHHHHHHCCHHHCCC
>Mature Secondary Structure 
TLKTNIALEGEELRFQMPEADDIISPENLSTIEFSLKAVPEKPDIASCKEVPGLVGLSK
EEECEEEECCHHHEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHCCCCCCCCH
EEAESKLQEAGFKAGEILEKESSTSQGTVIGQLPSDGSLAAPGAAVDLIISKIISLKVPD
HHHHHHHHHCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHEECCC
FSGLSLEAAKALIEKSRLRLEGVKEKPSDKTPGIVLAQSLPPGSEVSVDTTIVLTVSIAV
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCEECEEEEEEEEEEE
FKVPNLLGLELESAKQVIDKSGLLPGSIKEQLVSSGKPGIVLAQSLKPGAEVEKYSKIDL
HHCCCHHCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCHHHHCEEEE
VVSAGKIGSVIEAPLNTFPETAAKKPVNKILSETASKLQPETTFKVSGETPSTAPLETQV
EEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEE
KISAEPQVRTHAEPSVKLVPDIIGMPLEKAISLLGAQEIKAGTVSEAVSTAAAGTVISQN
EEECCCCEECCCCCCCEECHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEECC
PGAGSMVNMSVPVNLTVSKKAPVTQLRSNTISRIKL
CCCCCEEEEEEEEEEEECCCCCHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]