Click here to switch to the map view.

The map label for this gene is mat [H]

Identifier: 21228178

GI number: 21228178

Start: 2476039

End: 2477271

Strand: Reverse

Name: mat [H]

Synonym: MM_2076

Alternate gene names: 21228178

Gene position: 2477271-2476039 (Counterclockwise)

Preceding gene: 21228179

Following gene: 21228176

Centisome position: 60.48

GC content: 48.09

Gene sequence:

>1233_bases
TTGAGAAATATTGTTATAGAAGAGTTGAAAGCTTCGGAAGTCTACCGGCAAAAGGTAGAGGTTGTTGAAAGAAAAGGGCT
CGGGCACCCGGACTATATCTGCGATGCAATTATGGAACAGATTTCCGTAAACCTGAGCCAGAAATACCTTGAGACTTTCG
GAACCATCCTGCACCACAACATAGACAAGGGTATGCTTGTTGCAGGGCAGGTAGAAGGAAAATTTCTGGGGGGAAGGGTT
GTAAGCCCTATGAGGCTGATAATCGGAGACAGGGCAACCTTCGAATACGAAGGGACCGAGATCGATGTTTCCGGGCTTGC
TGTTGACACGGCAAAAGAATGGTTCTCGGAAAAACTCCGTTTTGTGGACGCTGAAAGTGTCATTTACCAGGTTGAACTTA
AAAAGGGATCTGCAGAACTTACTGACATCTTCAGCAGAGGTGGGAAGGTACTCGGGGCAAACGATACCTCTGCAGCGGTC
GGATATGCGCCTCTGAGCTCAACGGAGAGGCTGGTGCTAGAGACCGAGCGCTACCTTAACTCAAGGGGGTTCAAGAAAGA
ATATCCGGAGTCGGGAGAAGATATAAAGGTCATGGGGCTCAGGCATAAAGAGAATGTTCACCTCACGGTTGCTGCTCCTT
TTGTGGACATGTATGTTGAATCTGAAGATGACTATTTTAAAAAGAAGATAGAACTTCACGACAGGATAGAAGAGTTTACT
GCCGGGTTTGCGGAAAAAGAAAGAACTGAGCCTGAAGCCTGCATATGTGCAAGACCCACGGCTTCCCTTAACACCCTTGA
CATGCCTGGAAGGGGGATGGAAGGAATTTACACAACAGTTACCGGAACTTCTGCAGAAGACGCAGACTGCGGAGAGGTGG
GGCGTGGAAACCGCGTAAACGGGATAATTCCTTTAAACCGCCCTGTAAGCAGTGAGGCTGCAGCAGGGAAAAACCCCGTG
AGCCACATAGGAAAGATCTATAATCTCCTCTCCCACAGGATAGCCGCAGAGATTTACAGGCAGGTGCCTGATGTCTCGGA
GGTATATGTCTGGCTCCTGAGTGAGATCGGAACCCCTATTGACCAGCCCCAGATTGCAACTGCCCAGTTGATAATGAAAA
AAGGTGCAGCGGATGACGTTGAAAAAGAGGCAGCAGAAGTTATAGAAAAAGAACTTGACGATATCCATTCCTTTTCAATG
GAACTTGTAGCAGGGAAGAGACCTATCTGCTGA

Upstream 100 bases:

>100_bases
TTACAGGTCATTAACAAATATGGATGAACTATTTGGACCATATCCGTAACATCAAATCGGCATCTACTGCGCCCTTAAGG
GCAATCTGGGGGGAAAGACT

Downstream 100 bases:

>100_bases
AAAAACCAGTAAAAATTTTTCTGTCAAATTTGACTGCTAAATAAAAGATGGAATAGTAAGAGGTAGAATAATAAGAGATC
AAATCTTGACAGATTATTAA

Product: S-adenosylmethionine synthetase

Products: NA

Alternate protein names: AdoMet synthase; Methionine adenosyltransferase [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MRNIVIEELKASEVYRQKVEVVERKGLGHPDYICDAIMEQISVNLSQKYLETFGTILHHNIDKGMLVAGQVEGKFLGGRV
VSPMRLIIGDRATFEYEGTEIDVSGLAVDTAKEWFSEKLRFVDAESVIYQVELKKGSAELTDIFSRGGKVLGANDTSAAV
GYAPLSSTERLVLETERYLNSRGFKKEYPESGEDIKVMGLRHKENVHLTVAAPFVDMYVESEDDYFKKKIELHDRIEEFT
AGFAEKERTEPEACICARPTASLNTLDMPGRGMEGIYTTVTGTSAEDADCGEVGRGNRVNGIIPLNRPVSSEAAAGKNPV
SHIGKIYNLLSHRIAAEIYRQVPDVSEVYVWLLSEIGTPIDQPQIATAQLIMKKGAADDVEKEAAEVIEKELDDIHSFSM
ELVAGKRPIC

Sequences:

>Translated_410_residues
MRNIVIEELKASEVYRQKVEVVERKGLGHPDYICDAIMEQISVNLSQKYLETFGTILHHNIDKGMLVAGQVEGKFLGGRV
VSPMRLIIGDRATFEYEGTEIDVSGLAVDTAKEWFSEKLRFVDAESVIYQVELKKGSAELTDIFSRGGKVLGANDTSAAV
GYAPLSSTERLVLETERYLNSRGFKKEYPESGEDIKVMGLRHKENVHLTVAAPFVDMYVESEDDYFKKKIELHDRIEEFT
AGFAEKERTEPEACICARPTASLNTLDMPGRGMEGIYTTVTGTSAEDADCGEVGRGNRVNGIIPLNRPVSSEAAAGKNPV
SHIGKIYNLLSHRIAAEIYRQVPDVSEVYVWLLSEIGTPIDQPQIATAQLIMKKGAADDVEKEAAEVIEKELDDIHSFSM
ELVAGKRPIC
>Mature_410_residues
MRNIVIEELKASEVYRQKVEVVERKGLGHPDYICDAIMEQISVNLSQKYLETFGTILHHNIDKGMLVAGQVEGKFLGGRV
VSPMRLIIGDRATFEYEGTEIDVSGLAVDTAKEWFSEKLRFVDAESVIYQVELKKGSAELTDIFSRGGKVLGANDTSAAV
GYAPLSSTERLVLETERYLNSRGFKKEYPESGEDIKVMGLRHKENVHLTVAAPFVDMYVESEDDYFKKKIELHDRIEEFT
AGFAEKERTEPEACICARPTASLNTLDMPGRGMEGIYTTVTGTSAEDADCGEVGRGNRVNGIIPLNRPVSSEAAAGKNPV
SHIGKIYNLLSHRIAAEIYRQVPDVSEVYVWLLSEIGTPIDQPQIATAQLIMKKGAADDVEKEAAEVIEKELDDIHSFSM
ELVAGKRPIC

Specific function: Catalyzes the formation of S-adenosylmethionine from methionine and ATP [H]

COG id: COG1812

COG function: function code E; Archaeal S-adenosylmethionine synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AdoMet synthase 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002795
- ProDom:   PD011777 [H]

Pfam domain/function: PF01941 AdoMet_Synthase [H]

EC number: =2.5.1.6 [H]

Molecular weight: Translated: 45395; Mature: 45395

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNIVIEELKASEVYRQKVEVVERKGLGHPDYICDAIMEQISVNLSQKYLETFGTILHHN
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IDKGMLVAGQVEGKFLGGRVVSPMRLIIGDRATFEYEGTEIDVSGLAVDTAKEWFSEKLR
CCCCEEEEEEECCEEECCCCCCCHHHEECCCEEEEECCCEEEECCEEHHHHHHHHHHHHH
FVDAESVIYQVELKKGSAELTDIFSRGGKVLGANDTSAAVGYAPLSSTERLVLETERYLN
HCCCCCEEEEEEECCCCHHHHHHHHCCCEEEECCCCCCEEEECCCCCCCHHHHHHHHHHH
SRGFKKEYPESGEDIKVMGLRHKENVHLTVAAPFVDMYVESEDDYFKKKIELHDRIEEFT
CCCCCCCCCCCCCCEEEEEEEECCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHH
AGFAEKERTEPEACICARPTASLNTLDMPGRGMEGIYTTVTGTSAEDADCGEVGRGNRVN
CCHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
GIIPLNRPVSSEAAAGKNPVSHIGKIYNLLSHRIAAEIYRQVPDVSEVYVWLLSEIGTPI
EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
DQPQIATAQLIMKKGAADDVEKEAAEVIEKELDDIHSFSMELVAGKRPIC
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRNIVIEELKASEVYRQKVEVVERKGLGHPDYICDAIMEQISVNLSQKYLETFGTILHHN
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IDKGMLVAGQVEGKFLGGRVVSPMRLIIGDRATFEYEGTEIDVSGLAVDTAKEWFSEKLR
CCCCEEEEEEECCEEECCCCCCCHHHEECCCEEEEECCCEEEECCEEHHHHHHHHHHHHH
FVDAESVIYQVELKKGSAELTDIFSRGGKVLGANDTSAAVGYAPLSSTERLVLETERYLN
HCCCCCEEEEEEECCCCHHHHHHHHCCCEEEECCCCCCEEEECCCCCCCHHHHHHHHHHH
SRGFKKEYPESGEDIKVMGLRHKENVHLTVAAPFVDMYVESEDDYFKKKIELHDRIEEFT
CCCCCCCCCCCCCCEEEEEEEECCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHH
AGFAEKERTEPEACICARPTASLNTLDMPGRGMEGIYTTVTGTSAEDADCGEVGRGNRVN
CCHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
GIIPLNRPVSSEAAAGKNPVSHIGKIYNLLSHRIAAEIYRQVPDVSEVYVWLLSEIGTPI
EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
DQPQIATAQLIMKKGAADDVEKEAAEVIEKELDDIHSFSMELVAGKRPIC
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]