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The map label for this gene is fecD [C]

Identifier: 21228170

GI number: 21228170

Start: 2462688

End: 2463758

Strand: Reverse

Name: fecD [C]

Synonym: MM_2068

Alternate gene names: 21228170

Gene position: 2463758-2462688 (Counterclockwise)

Preceding gene: 21228171

Following gene: 21228169

Centisome position: 60.15

GC content: 48.27

Gene sequence:

>1071_bases
GTGCATTTTGCCGACGGAGCAGTTCCAGAAGATTACCTCGTATATGTGCGAAGAAAATTCTTCTGGATTATGGGGGGGCT
CCTGCTCCTATTTATTATGCTCATATACTCAATCTCTGTAGGAGCAGTAACAATACCTCCTTATGAGGTCCTGCAAACCC
TGATGGGGCAGAGTGTCTCTACAAAATGGGACTCAATAATCTGGAATATACGCCTCCCTCAAGCCCTTGCTGCAATAGTG
GCCGGAGCCGGTCTCTCAGTTGCGGGAGTCGTAATGCAATCTATCCTGCGCAATCCACTCGGGTCTCCTTTCACCCTTGG
AATCTCCAATGCAGGAGCATTCGGAGCTGCAGTTTCGGTAATTATCCTTGGCACAGGAAAAATGCAATCAACCGCTGCAG
ACGCTGTCATAATTAACAACCCTTACATGACCACGATTGTGGCTTTTATTTTCTGTCTCCTCGCTACCGGGATAATCCTG
CTTATCTCCAGGATACGGGCAGCTTCACCCGAAGTGATGGTGCTTGCAGGAGTGGCTCTTTCTTCCCTCTTTACCGCAGG
AACGATGTTCCTTCAGTACTTTGCTGACGATACCCAGCTCGCAGCAGTTGTGTTCTGGACCTTTGGCGATGTTGGAAGAG
CAAACTGGCTGGAATTTAAGATTATGGCAGTTGTTGTCCTGCTTTCAACTCTGTTCTTTATGATCAACCGCTGGGACTAC
AATGCCATAGACGCAGGAGACGAGACCGCGAAAGGTCTTGGAGTCAACGTGGAAAGAGTCAGGATGGTAGGCATGATTGT
TGCAGCTCTAGTATCTGCCGTTATTGTTTCTTTCCTTGGAGTAATCGGATTTGTAGGACTGATCTGCCCTCATATGGTAA
GGAGACTCATAGGGGATGACCAGAGATACCTCATCCCGGGTTCAACTCTGCTTGGTGGAATTCTTCTCCTGGCATCTGAC
ACGGCAGCCAGGATCATAATATCACCATATGTGCTTCCTGTCTCCATACTTACTGCTTTCATGGGAGCACCGACTTTCAT
TTACCTGCTTCTCAGGGGGTATAGACGATGA

Upstream 100 bases:

>100_bases
CACATTCTTCGTTGGAAAACCTGTGTTCTCTGACCTTAACGGACAGTACAACGACACCGGCTTCAAGCAGATTCCGCTAT
AACACGGAGGGTACAAATAA

Downstream 100 bases:

>100_bases
TTCTATCTGTAGAAGAACTTCAGTTTTTGTATCGTAACCGTAAGATCCTGCATGAGATTGCCTTTACAATCGATGAAGGA
GAAGTTGTAGCAATTCTGGG

Product: Iron(III) dicitrate transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MHFADGAVPEDYLVYVRRKFFWIMGGLLLLFIMLIYSISVGAVTIPPYEVLQTLMGQSVSTKWDSIIWNIRLPQALAAIV
AGAGLSVAGVVMQSILRNPLGSPFTLGISNAGAFGAAVSVIILGTGKMQSTAADAVIINNPYMTTIVAFIFCLLATGIIL
LISRIRAASPEVMVLAGVALSSLFTAGTMFLQYFADDTQLAAVVFWTFGDVGRANWLEFKIMAVVVLLSTLFFMINRWDY
NAIDAGDETAKGLGVNVERVRMVGMIVAALVSAVIVSFLGVIGFVGLICPHMVRRLIGDDQRYLIPGSTLLGGILLLASD
TAARIIISPYVLPVSILTAFMGAPTFIYLLLRGYRR

Sequences:

>Translated_356_residues
MHFADGAVPEDYLVYVRRKFFWIMGGLLLLFIMLIYSISVGAVTIPPYEVLQTLMGQSVSTKWDSIIWNIRLPQALAAIV
AGAGLSVAGVVMQSILRNPLGSPFTLGISNAGAFGAAVSVIILGTGKMQSTAADAVIINNPYMTTIVAFIFCLLATGIIL
LISRIRAASPEVMVLAGVALSSLFTAGTMFLQYFADDTQLAAVVFWTFGDVGRANWLEFKIMAVVVLLSTLFFMINRWDY
NAIDAGDETAKGLGVNVERVRMVGMIVAALVSAVIVSFLGVIGFVGLICPHMVRRLIGDDQRYLIPGSTLLGGILLLASD
TAARIIISPYVLPVSILTAFMGAPTFIYLLLRGYRR
>Mature_356_residues
MHFADGAVPEDYLVYVRRKFFWIMGGLLLLFIMLIYSISVGAVTIPPYEVLQTLMGQSVSTKWDSIIWNIRLPQALAAIV
AGAGLSVAGVVMQSILRNPLGSPFTLGISNAGAFGAAVSVIILGTGKMQSTAADAVIINNPYMTTIVAFIFCLLATGIIL
LISRIRAASPEVMVLAGVALSSLFTAGTMFLQYFADDTQLAAVVFWTFGDVGRANWLEFKIMAVVVLLSTLFFMINRWDY
NAIDAGDETAKGLGVNVERVRMVGMIVAALVSAVIVSFLGVIGFVGLICPHMVRRLIGDDQRYLIPGSTLLGGILLLASD
TAARIIISPYVLPVSILTAFMGAPTFIYLLLRGYRR

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=330, Percent_Identity=31.5151515151515, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788004, Length=300, Percent_Identity=31.3333333333333, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1790741, Length=332, Percent_Identity=28.9156626506024, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1786347, Length=287, Percent_Identity=31.7073170731707, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786805, Length=323, Percent_Identity=30.6501547987616, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786804, Length=329, Percent_Identity=29.1793313069909, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 38359; Mature: 38359

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFADGAVPEDYLVYVRRKFFWIMGGLLLLFIMLIYSISVGAVTIPPYEVLQTLMGQSVS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHCCCCC
TKWDSIIWNIRLPQALAAIVAGAGLSVAGVVMQSILRNPLGSPFTLGISNAGAFGAAVSV
CCHHHEEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHEEE
IILGTGKMQSTAADAVIINNPYMTTIVAFIFCLLATGIILLISRIRAASPEVMVLAGVAL
EEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHH
SSLFTAGTMFLQYFADDTQLAAVVFWTFGDVGRANWLEFKIMAVVVLLSTLFFMINRWDY
HHHHHHHHHHHHHHCCCCCEEHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
NAIDAGDETAKGLGVNVERVRMVGMIVAALVSAVIVSFLGVIGFVGLICPHMVRRLIGDD
CCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QRYLIPGSTLLGGILLLASDTAARIIISPYVLPVSILTAFMGAPTFIYLLLRGYRR
CEEEECCHHHHHHHHHHCCCCHHEEEECCHHHHHHHHHHHHCHHHHHHHHHHHCCC
>Mature Secondary Structure
MHFADGAVPEDYLVYVRRKFFWIMGGLLLLFIMLIYSISVGAVTIPPYEVLQTLMGQSVS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHCCCCC
TKWDSIIWNIRLPQALAAIVAGAGLSVAGVVMQSILRNPLGSPFTLGISNAGAFGAAVSV
CCHHHEEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHEEE
IILGTGKMQSTAADAVIINNPYMTTIVAFIFCLLATGIILLISRIRAASPEVMVLAGVAL
EEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHH
SSLFTAGTMFLQYFADDTQLAAVVFWTFGDVGRANWLEFKIMAVVVLLSTLFFMINRWDY
HHHHHHHHHHHHHHCCCCCEEHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
NAIDAGDETAKGLGVNVERVRMVGMIVAALVSAVIVSFLGVIGFVGLICPHMVRRLIGDD
CCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QRYLIPGSTLLGGILLLASDTAARIIISPYVLPVSILTAFMGAPTFIYLLLRGYRR
CEEEECCHHHHHHHHHHCCCCHHEEEECCHHHHHHHHHHHHCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]