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The map label for this gene is mtbB

Identifier: 21228152

GI number: 21228152

Start: 2446279

End: 2446593

Strand: Reverse

Name: mtbB

Synonym: MM_2050

Alternate gene names: 21228152

Gene position: 2446593-2446279 (Counterclockwise)

Preceding gene: 21228153

Following gene: 21228151

Centisome position: 59.73

GC content: 41.27

Gene sequence:

>315_bases
ATGCCGATCTCCCACATAATGGCTTCAGGTATGACAGGAATGAGAGCAGCAGGAGACCTTGTTGCAAGGATGCAGTTCTC
AAAGAACATGAAGATTAAAGAGGCAAAGGAGTACGTGGCAAAGAAGCTTAATGTAGAAATCAGGGACCTTGCGGATGAAT
ACATTATGCGTGAACTCCGTGAAGAACTAAATATAGGAGTTATTACCTCGGTTCCGGGATCTGCAAAGGGAATTGCTGCA
AAAATGAATATTGAGAAGCTGCTTGGTATTAAGATTAACTCATGTGAACTCTTTAGAAAACAGACCGGAAAATAA

Upstream 100 bases:

>100_bases
TGAAACTCCTCCGATTGATGCAGTTACAAGGGCAAGCAAGGCAATGGTTGAGATTGCAGGAGTAGACGGCATATAGATCG
GGGTCGGCGACCCTCTGGGT

Downstream 100 bases:

>100_bases
CCCAGAGGTCAAGAACAAAAAGGAAAGTATGGAAAAAAACCGGAAGTAACCCGGGTCAGGAAAAAGGAAAGGCTAGAAAG
GTAGCAAAAAGCGGGGAAAG

Product: dimethylamine:corrinoid methyltransferase

Products: NA

Alternate protein names: DMA methyltransferase 1; DMAMT 1

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MPISHIMASGMTGMRAAGDLVARMQFSKNMKIKEAKEYVAKKLNVEIRDLADEYIMRELREELNIGVITSVPGSAKGIAA
KMNIEKLLGIKINSCELFRKQTGK

Sequences:

>Translated_104_residues
MPISHIMASGMTGMRAAGDLVARMQFSKNMKIKEAKEYVAKKLNVEIRDLADEYIMRELREELNIGVITSVPGSAKGIAA
KMNIEKLLGIKINSCELFRKQTGK
>Mature_103_residues
PISHIMASGMTGMRAAGDLVARMQFSKNMKIKEAKEYVAKKLNVEIRDLADEYIMRELREELNIGVITSVPGSAKGIAAK
MNIEKLLGIKINSCELFRKQTGK

Specific function: Catalyzes the transfer of a methyl group from dimethylamine to the corrinoid cofactor of mtbC

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dimethylamine methyltransferase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTBB1_METMA (P58970)

Other databases:

- EMBL:   AE008384
- EMBL:   AE008384
- RefSeq:   NP_634074.1
- RefSeq:   NP_634075.1
- GeneID:   1480392
- GeneID:   1480393
- BioCyc:   MMAZ192952:MM2050-MONOMER
- BioCyc:   MMAZ192952:MM2051-MONOMER
- GO:   GO:0015948
- InterPro:   IPR012653
- TIGRFAMs:   TIGR02368

Pfam domain/function: PF09505 Dimeth_Pyl

EC number: NA

Molecular weight: Translated: 11571; Mature: 11440

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
7.7 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
6.8 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPISHIMASGMTGMRAAGDLVARMQFSKNMKIKEAKEYVAKKLNVEIRDLADEYIMRELR
CCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EELNIGVITSVPGSAKGIAAKMNIEKLLGIKINSCELFRKQTGK
HHCCCCEEECCCCCCCCEEHHCCHHHHHCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
PISHIMASGMTGMRAAGDLVARMQFSKNMKIKEAKEYVAKKLNVEIRDLADEYIMRELR
CHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EELNIGVITSVPGSAKGIAAKMNIEKLLGIKINSCELFRKQTGK
HHCCCCEEECCCCCCCCEEHHCCHHHHHCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824