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The map label for this gene is mttB [H]

Identifier: 21228151

GI number: 21228151

Start: 2444654

End: 2445655

Strand: Reverse

Name: mttB [H]

Synonym: MM_2049

Alternate gene names: 21228151

Gene position: 2445655-2444654 (Counterclockwise)

Preceding gene: 21228152

Following gene: 21228150

Centisome position: 59.7

GC content: 49.8

Gene sequence:

>1002_bases
ATGGCGCAAAATAATGCAGTTGCAGGATTCAACGCACTTAATGGCGTAGAATTAAGCCTTTTTACTACCGATGAACTCAA
AGCAATTCACTATGCCACAATGGAAGTTCTGATGAACCCGGGTGTTCAGGTATCGGACCCTGAAGCAAGGCAGATCTTCA
AAGAAAATGGCTGTGAAGTTGACGAAAAAACCAGTATTGTAAAGATCCCCGAATACCTTGTAAGGAGAGCCCTTCAGCTT
GCGCCTTCAAGGTTCGTTCTCTGGGGCAGGGACAAAAAGTACAACACTGTCCAGGAAGCAGGAGGCAAGGTACACTGGAC
CTGCTTCGGTACCGGTGTTAAGATGTGTAAGTACCAGGACGGAAAATACGTAACTGTTGACTCCGTGGAACAGGACATTG
CAGACATCGCAAAGCTCTGCGACTGGGCAGAAAATATCGATTACTTCTCACTTCCGGTATCCGCAAGGGACTGGGCTGGG
AAGGGCGCACAGGACGTCCATGAAACCCTTACCCCTATAGCAAATACTGCAAAACACTACCACCACATTGACCCTGTAGG
GGAACATGTCGATTACTACCGGGACATTGTAAAAGCCTATTACGGCGGCGATGAAGAAGAAGCAAGGAAAAAGCCTATCT
TTTCCATGCTGCTCTGCCCTACAAGCCCGCTTGAACTCAGCGTCAATGCCTGCCAGGTCATAATCAGGGGTGCACGCTTC
GGAATGCCTGTGAATGTCCTGAGCATGGCAATGTCAGGCGGATCGTCCCCTGTGTACCTTGCAGGGACCCTTGTGACCCA
TAATGCCGAAGTCCTTTCAGGAATTGTTCTTGCCCAGCTGACAGTGCCCGGAGCTAAAGTCTGGTACGGAAGCTCAACAA
CCACTTTTGACCTGAAGAAAGGCACTGCCCCTGTAGGATCTCCAGAACTCGGCTTGATAAGTGCTGCTGTAGCAAAACTT
GCCCAGTTCTATGGCCTGCCTTCCTATGTTGCAGGCACCTAG

Upstream 100 bases:

>100_bases
TGCACCCTGAATCGAAGATAAAAGAATTTGCCCTGAGTAAGACAAACTCAGCTGATGAGAGGAAGCAAACCGGAAATATT
CAGGAAAAAGGAGATAGAGA

Downstream 100 bases:

>100_bases
TCTGATGCCAAGATCCCGGACAACCAGGCAGGACACGAAAAGACAATGACATGTCTCCTCCCGGCGCTTGCCGGAGCAAA
TACCATCTACGGAGCCGGGA

Product: trimethylamine:corrinoid methyltransferase

Products: NA

Alternate protein names: TMA methyltransferase 1 [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MAQNNAVAGFNALNGVELSLFTTDELKAIHYATMEVLMNPGVQVSDPEARQIFKENGCEVDEKTSIVKIPEYLVRRALQL
APSRFVLWGRDKKYNTVQEAGGKVHWTCFGTGVKMCKYQDGKYVTVDSVEQDIADIAKLCDWAENIDYFSLPVSARDWAG
KGAQDVHETLTPIANTAKHYHHIDPVGEHVDYYRDIVKAYYGGDEEEARKKPIFSMLLCPTSPLELSVNACQVIIRGARF
GMPVNVLSMAMSGGSSPVYLAGTLVTHNAEVLSGIVLAQLTVPGAKVWYGSSTTTFDLKKGTAPVGSPELGLISAAVAKL
AQFYGLPSYVAGT

Sequences:

>Translated_333_residues
MAQNNAVAGFNALNGVELSLFTTDELKAIHYATMEVLMNPGVQVSDPEARQIFKENGCEVDEKTSIVKIPEYLVRRALQL
APSRFVLWGRDKKYNTVQEAGGKVHWTCFGTGVKMCKYQDGKYVTVDSVEQDIADIAKLCDWAENIDYFSLPVSARDWAG
KGAQDVHETLTPIANTAKHYHHIDPVGEHVDYYRDIVKAYYGGDEEEARKKPIFSMLLCPTSPLELSVNACQVIIRGARF
GMPVNVLSMAMSGGSSPVYLAGTLVTHNAEVLSGIVLAQLTVPGAKVWYGSSTTTFDLKKGTAPVGSPELGLISAAVAKL
AQFYGLPSYVAGT
>Mature_332_residues
AQNNAVAGFNALNGVELSLFTTDELKAIHYATMEVLMNPGVQVSDPEARQIFKENGCEVDEKTSIVKIPEYLVRRALQLA
PSRFVLWGRDKKYNTVQEAGGKVHWTCFGTGVKMCKYQDGKYVTVDSVEQDIADIAKLCDWAENIDYFSLPVSARDWAGK
GAQDVHETLTPIANTAKHYHHIDPVGEHVDYYRDIVKAYYGGDEEEARKKPIFSMLLCPTSPLELSVNACQVIIRGARFG
MPVNVLSMAMSGGSSPVYLAGTLVTHNAEVLSGIVLAQLTVPGAKVWYGSSTTTFDLKKGTAPVGSPELGLISAAVAKLA
QFYGLPSYVAGT

Specific function: Catalyzes probably the transfer of a methyl group from trimethylamine to the corrinoid cofactor of mttC [H]

COG id: COG5598

COG function: function code H; Trimethylamine:corrinoid methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trimethylamine methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010426
- InterPro:   IPR012740 [H]

Pfam domain/function: PF06253 MTTB [H]

EC number: NA

Molecular weight: Translated: 36233; Mature: 36101

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQNNAVAGFNALNGVELSLFTTDELKAIHYATMEVLMNPGVQVSDPEARQIFKENGCEV
CCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
DEKTSIVKIPEYLVRRALQLAPSRFVLWGRDKKYNTVQEAGGKVHWTCFGTGVKMCKYQD
CCCCCEEEHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHCCCEEEEEEECCCEEEEEECC
GKYVTVDSVEQDIADIAKLCDWAENIDYFSLPVSARDWAGKGAQDVHETLTPIANTAKHY
CCEEECCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
HHIDPVGEHVDYYRDIVKAYYGGDEEEARKKPIFSMLLCPTSPLELSVNACQVIIRGARF
HCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCHHEEEECCCCCCEEEHHHHHHHHHHHHC
GMPVNVLSMAMSGGSSPVYLAGTLVTHNAEVLSGIVLAQLTVPGAKVWYGSSTTTFDLKK
CCCHHHHHHHHCCCCCCEEEEEEEEECCHHHHHHHHHEEEECCCCEEEECCCCEEEEECC
GTAPVGSPELGLISAAVAKLAQFYGLPSYVAGT
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
AQNNAVAGFNALNGVELSLFTTDELKAIHYATMEVLMNPGVQVSDPEARQIFKENGCEV
CCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
DEKTSIVKIPEYLVRRALQLAPSRFVLWGRDKKYNTVQEAGGKVHWTCFGTGVKMCKYQD
CCCCCEEEHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHCCCEEEEEEECCCEEEEEECC
GKYVTVDSVEQDIADIAKLCDWAENIDYFSLPVSARDWAGKGAQDVHETLTPIANTAKHY
CCEEECCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
HHIDPVGEHVDYYRDIVKAYYGGDEEEARKKPIFSMLLCPTSPLELSVNACQVIIRGARF
HCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCHHEEEECCCCCCEEEHHHHHHHHHHHHC
GMPVNVLSMAMSGGSSPVYLAGTLVTHNAEVLSGIVLAQLTVPGAKVWYGSSTTTFDLKK
CCCHHHHHHHHCCCCCCEEEEEEEEECCHHHHHHHHHEEEECCCCEEEECCCCEEEEECC
GTAPVGSPELGLISAAVAKLAQFYGLPSYVAGT
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]