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The map label for this gene is yhcC [C]

Identifier: 21228076

GI number: 21228076

Start: 2344103

End: 2345770

Strand: Reverse

Name: yhcC [C]

Synonym: MM_1974

Alternate gene names: 21228076

Gene position: 2345770-2344103 (Counterclockwise)

Preceding gene: 21228077

Following gene: 21228075

Centisome position: 57.26

GC content: 47.12

Gene sequence:

>1668_bases
ATGACCCTAAAGACGGAATTTGAGATGAAAGAAGCTGATTACAACAGGGCCTGCAGGAACATCCTTGAAAAGGTGCTTGC
CGGGGAAATAAAAGACGAAGACCAGTTAAACAAAGTGAAAAAAGATGTGAGTAAGCTGTATCATCTTGCCAGCCTGCCTA
GAAATGGGGATATTATTATGCAGGGCACACCTGAGGAGCAGGCTCTAATAAAAGAGTTCCTCAGGAGAAAACCCGTAAGG
ACGATTTCCGGAGTCGCGGTAATTGCTGTAATGACCTCTCCTGCCCCATGCCCTCACGGGGTTTGCCTGCCCTGTCCGGG
AGGTCCGAATTCCTCATTTAAATCCCCTCAGAGCTACATGGGAAGGGAACCTGCAGCAATGAGAGCAATTCAGCATGAAT
TTGACCCTTACTCCCAGGTTCAGTCCAGGCTTTCCCAGCTAAAAGAGATAGGGCATGATGTTGAAAAAGTTGAGCTTATA
GTGATGGGAGGCACTTTTTCAGCACGCAGCCTTGACTATCAGGAATGGTTTACCAAACGCTGCCTTGAAGCAATGAACGA
TTTTACAGGCATGGAATGGAGGGATAAAGCCTGGACGATCGGAAAGTCCTTGCCTTATGTTCCGCTTGAAGAGGTTCAGA
AAGCAAACGAAACAGCTGACATCCGAAACGTTGGCATAACCTTTGAGACAAGACCTGATTGGGCAAGAGAAGAACATGTA
GACGAATTCCTCAGGCTTGGAGGGACAAAGGTAGAGATTGGAGTCCAGAGCGTTTATGATTTTGTATTATCCCGGATGCA
GAGAGGGCATGGAGTTGCAGAAATTGTCAGAGCTAACAGGGTATTAAGAGACAGTGCATTTAAAGTAGGCTTTCACATGA
TGCCTCACCTTCCTGGAGCGGACTCCGAACTTGACCTGAGGGGATTTAAAAAGCTCTTCGATGACCAGCGTTTCAGGCCG
GATTACCTGAAAATATATCCTACCCTTGTAACCGAAGGCACCCCCCTGTACAGAATGTGGAAATCCGGAGAATATCAGGC
TCTTTCAGACGAAGAAGCTGCAGAACTTGTCGCAGATATAAAGGCTGTCCTGCCTAAATGGGTAAGGCTTCAGCGCATCC
AGAGGGATATTCCTGCCCACCAGATCTTTGCAGGCGTGAGGAAAAGTAACCTAAGGCAGCTTGCAGAGGAGAAACTCCGG
GAAAAGGGAGGGAAATGCCGCTGCATACGCTGCAGAGAGGTCGGACACAACAGCCTGAAAGGAAGAAGGATAAATGAAAA
AGACATCGAGCTTACTGTGGAATCTTACGAAGCCTGTAACGGTAAAGAACACTTCATCGCTTTTGAAGACCTTTCGGCAG
ATGTCCTGATAGGTTTTACACGTTTGCGTTTCCCTGCCGAACCTCACAGAGAAGAACTGCAGGGCTCTGCACTTATAAGG
GAACTGCATGTTTACGGCTCCATGGTGCCTGTAGGAAAAGGCGCAAAACAAAAAGAATGGCAACACAGGGGTTATGGAAA
GGAACTTATTGAACATGCAGAAAAAACGGCATCCGAATCCGGCTACGGCAAGCTTTCTATAATTAGCGGAATAGGCGCAA
GGGAATATTATAGGAAACTGGGATACGATCTTGACGGAGTATACATGTCAAAACCCCTGAAGGATTAA

Upstream 100 bases:

>100_bases
TAAAAACAGGAATTTAAAATTTATGAATCCCTCCCTGGAACCTGATTACAAGTTCAGGTTAAGGATTTCAGTTGCAGATG
CCAATGAAAGAGCCTGGAAT

Downstream 100 bases:

>100_bases
AAAATGGAGATATGAAATAACCGGAGACCGGATTTTCCAGCCAGGCAATATATTAACCACCTTGGGCTCTGGAATTCATC
CGGAGCCCCAGGTTATTGAG

Product: histone acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MTLKTEFEMKEADYNRACRNILEKVLAGEIKDEDQLNKVKKDVSKLYHLASLPRNGDIIMQGTPEEQALIKEFLRRKPVR
TISGVAVIAVMTSPAPCPHGVCLPCPGGPNSSFKSPQSYMGREPAAMRAIQHEFDPYSQVQSRLSQLKEIGHDVEKVELI
VMGGTFSARSLDYQEWFTKRCLEAMNDFTGMEWRDKAWTIGKSLPYVPLEEVQKANETADIRNVGITFETRPDWAREEHV
DEFLRLGGTKVEIGVQSVYDFVLSRMQRGHGVAEIVRANRVLRDSAFKVGFHMMPHLPGADSELDLRGFKKLFDDQRFRP
DYLKIYPTLVTEGTPLYRMWKSGEYQALSDEEAAELVADIKAVLPKWVRLQRIQRDIPAHQIFAGVRKSNLRQLAEEKLR
EKGGKCRCIRCREVGHNSLKGRRINEKDIELTVESYEACNGKEHFIAFEDLSADVLIGFTRLRFPAEPHREELQGSALIR
ELHVYGSMVPVGKGAKQKEWQHRGYGKELIEHAEKTASESGYGKLSIISGIGAREYYRKLGYDLDGVYMSKPLKD

Sequences:

>Translated_555_residues
MTLKTEFEMKEADYNRACRNILEKVLAGEIKDEDQLNKVKKDVSKLYHLASLPRNGDIIMQGTPEEQALIKEFLRRKPVR
TISGVAVIAVMTSPAPCPHGVCLPCPGGPNSSFKSPQSYMGREPAAMRAIQHEFDPYSQVQSRLSQLKEIGHDVEKVELI
VMGGTFSARSLDYQEWFTKRCLEAMNDFTGMEWRDKAWTIGKSLPYVPLEEVQKANETADIRNVGITFETRPDWAREEHV
DEFLRLGGTKVEIGVQSVYDFVLSRMQRGHGVAEIVRANRVLRDSAFKVGFHMMPHLPGADSELDLRGFKKLFDDQRFRP
DYLKIYPTLVTEGTPLYRMWKSGEYQALSDEEAAELVADIKAVLPKWVRLQRIQRDIPAHQIFAGVRKSNLRQLAEEKLR
EKGGKCRCIRCREVGHNSLKGRRINEKDIELTVESYEACNGKEHFIAFEDLSADVLIGFTRLRFPAEPHREELQGSALIR
ELHVYGSMVPVGKGAKQKEWQHRGYGKELIEHAEKTASESGYGKLSIISGIGAREYYRKLGYDLDGVYMSKPLKD
>Mature_554_residues
TLKTEFEMKEADYNRACRNILEKVLAGEIKDEDQLNKVKKDVSKLYHLASLPRNGDIIMQGTPEEQALIKEFLRRKPVRT
ISGVAVIAVMTSPAPCPHGVCLPCPGGPNSSFKSPQSYMGREPAAMRAIQHEFDPYSQVQSRLSQLKEIGHDVEKVELIV
MGGTFSARSLDYQEWFTKRCLEAMNDFTGMEWRDKAWTIGKSLPYVPLEEVQKANETADIRNVGITFETRPDWAREEHVD
EFLRLGGTKVEIGVQSVYDFVLSRMQRGHGVAEIVRANRVLRDSAFKVGFHMMPHLPGADSELDLRGFKKLFDDQRFRPD
YLKIYPTLVTEGTPLYRMWKSGEYQALSDEEAAELVADIKAVLPKWVRLQRIQRDIPAHQIFAGVRKSNLRQLAEEKLRE
KGGKCRCIRCREVGHNSLKGRRINEKDIELTVESYEACNGKEHFIAFEDLSADVLIGFTRLRFPAEPHREELQGSALIRE
LHVYGSMVPVGKGAKQKEWQHRGYGKELIEHAEKTASESGYGKLSIISGIGAREYYRKLGYDLDGVYMSKPLKD

Specific function: Unknown

COG id: COG1243

COG function: function code KB; Histone acetyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI23510283, Length=533, Percent_Identity=43.9024390243902, Blast_Score=416, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI133955098, Length=534, Percent_Identity=43.4456928838951, Blast_Score=410, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6325171, Length=564, Percent_Identity=40.6028368794326, Blast_Score=413, Evalue=1e-116,
Organism=Drosophila melanogaster, GI19920684, Length=544, Percent_Identity=41.7279411764706, Blast_Score=408, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR006638
- InterPro:   IPR005910
- InterPro:   IPR007197 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 63211; Mature: 63080

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKTEFEMKEADYNRACRNILEKVLAGEIKDEDQLNKVKKDVSKLYHLASLPRNGDIIM
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEE
QGTPEEQALIKEFLRRKPVRTISGVAVIAVMTSPAPCPHGVCLPCPGGPNSSFKSPQSYM
ECCCHHHHHHHHHHHHCCCHHHCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCHHHH
GREPAAMRAIQHEFDPYSQVQSRLSQLKEIGHDVEKVELIVMGGTFSARSLDYQEWFTKR
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCCHHHHHHHH
CLEAMNDFTGMEWRDKAWTIGKSLPYVPLEEVQKANETADIRNVGITFETRPDWAREEHV
HHHHHHHHCCCCCCCCHHCCCCCCCCCCHHHHHHCCCCHHHHCCCEEEECCCCHHHHHHH
DEFLRLGGTKVEIGVQSVYDFVLSRMQRGHGVAEIVRANRVLRDSAFKVGFHMMPHLPGA
HHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DSELDLRGFKKLFDDQRFRPDYLKIYPTLVTEGTPLYRMWKSGEYQALSDEEAAELVADI
CCCCCHHHHHHHHCCCCCCCCHHEEEHHHHCCCCCHHHHHCCCCCCCCCCHHHHHHHHHH
KAVLPKWVRLQRIQRDIPAHQIFAGVRKSNLRQLAEEKLREKGGKCRCIRCREVGHNSLK
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHCCCCCCC
GRRINEKDIELTVESYEACNGKEHFIAFEDLSADVLIGFTRLRFPAEPHREELQGSALIR
CCCCCCCHHEEEEHHHHCCCCCCEEEEEECCCCCHHEEHHHHCCCCCCCHHHHHHHHHHH
ELHVYGSMVPVGKGAKQKEWQHRGYGKELIEHAEKTASESGYGKLSIISGIGAREYYRKL
HHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHH
GYDLDGVYMSKPLKD
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
TLKTEFEMKEADYNRACRNILEKVLAGEIKDEDQLNKVKKDVSKLYHLASLPRNGDIIM
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEE
QGTPEEQALIKEFLRRKPVRTISGVAVIAVMTSPAPCPHGVCLPCPGGPNSSFKSPQSYM
ECCCHHHHHHHHHHHHCCCHHHCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCHHHH
GREPAAMRAIQHEFDPYSQVQSRLSQLKEIGHDVEKVELIVMGGTFSARSLDYQEWFTKR
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCCHHHHHHHH
CLEAMNDFTGMEWRDKAWTIGKSLPYVPLEEVQKANETADIRNVGITFETRPDWAREEHV
HHHHHHHHCCCCCCCCHHCCCCCCCCCCHHHHHHCCCCHHHHCCCEEEECCCCHHHHHHH
DEFLRLGGTKVEIGVQSVYDFVLSRMQRGHGVAEIVRANRVLRDSAFKVGFHMMPHLPGA
HHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DSELDLRGFKKLFDDQRFRPDYLKIYPTLVTEGTPLYRMWKSGEYQALSDEEAAELVADI
CCCCCHHHHHHHHCCCCCCCCHHEEEHHHHCCCCCHHHHHCCCCCCCCCCHHHHHHHHHH
KAVLPKWVRLQRIQRDIPAHQIFAGVRKSNLRQLAEEKLREKGGKCRCIRCREVGHNSLK
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHCCCCCCC
GRRINEKDIELTVESYEACNGKEHFIAFEDLSADVLIGFTRLRFPAEPHREELQGSALIR
CCCCCCCHHEEEEHHHHCCCCCCEEEEEECCCCCHHEEHHHHCCCCCCCHHHHHHHHHHH
ELHVYGSMVPVGKGAKQKEWQHRGYGKELIEHAEKTASESGYGKLSIISGIGAREYYRKL
HHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHH
GYDLDGVYMSKPLKD
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]