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The map label for this gene is atoS [H]

Identifier: 21228033

GI number: 21228033

Start: 2298295

End: 2300019

Strand: Direct

Name: atoS [H]

Synonym: MM_1931

Alternate gene names: 21228033

Gene position: 2298295-2300019 (Clockwise)

Preceding gene: 21228031

Following gene: 21228034

Centisome position: 56.11

GC content: 42.14

Gene sequence:

>1725_bases
ATGGGAGCATTAATTTTTTCAGGGCTCATATCTACCTTACTTGCGATCAGGGCATACAAAGCCTATAATTGCCACAGATC
GCCTTTTGTAAAACATTTTACGTTAGTTATGCTCGGCATGACGCTCTGGTCTATAAATTATGCTTTTGAAATTGGGTTTA
TGGAACCCGGACAAAAATATTTCTTTGCCCGCCTCCAGTATCTTGGTCTCTCCTTTATTCCTGTATCCTGGTTTTTATTT
ACTTCCGAATATTCTGGGATAGGCATTCAATTTGCACGAAAATATGAAAAGCTGCTCTATCTTTTGCCCTGCTCTGTAAT
TCTGTTGATGGTCACGAATAATGTCCATGGGCTGTTTTTCGAATCTTTTCATCTTGATTACTCCAGAGAGTTTCCTCTCC
TTATAATTCAGCATGGATCGTTGTTCTGGATTTTTTATCTCTATTCTTTTGTTTTACTGGTTCTTGGAATCTTTCTCCTC
TTCAAGCAATTTGTCCGCCTTACTGCACCTTACGGTACCCAGGCAGGCATCGCTCTTACCGCAGCCTGTGTTCCGGTTCT
TGGGAATATACTTCATCTCGCAGATGTAGGACCTTTTGAATCCCTTGACCCTACTCCATTTTCTCTTGCAATAACCGGTT
TGATCCTTTTCTGGGGCACAATCCAGCATGAGTTTCTTAATATTATTCCAGTTGCCAGAGAAAACGTTATAGAATCCATG
AGCGATGGATATATTGTTGTGGATACTTCAAACTCAATAGTGGACGTTAACAGGGCGGTACTTGAACTTGCAGGGAAAAC
AAGAAAAGAGGTACTGGGAAAAAACTTAACTTACCTTTTCGGAGAAGGAGTGGAGCTTCTATGTCATACGCCTGAAGGAG
ATTTTGGCAGGGAGATTTCACTTAAAAGCGGTTCGGAAATTAAGTTTTTTACTGTCAGTGTCAGCCCCCTTATGGCAAGG
AATGAGCCAGAAGGTAAACTGATAATGATCCATGATATCACGGAGATACACAGATACCAGGAAGCACTGAAACAGGCAAA
TAAAAAAATTAACCTCATGAGCAATATTACAAGGCATGATATTCTCAATCAGGTAAACGTGCTTTCGGGATATACAGAAC
TGATCTCCGAGATGCTCCCTCTGGACGTAAGGGGAGACCCCAGGATCGCGAAGTACTTCAGGAATCTCAACAAAGGAATT
GAAACAATTCATAGCCAGATTATTTTCACAAAAGACTACCAGGAACTCGGAGTCGTTTCTCCTACATGGCAGTCTATATG
CAGCATTGCAAAAGAGGCAGCATTCGCCTTTTCAGGGCAGGGAATCAAGTTTTCTATAGAGGATAAAGGCCTTGAAATCT
ATGCTGACCCTCTGCTTAAAAAAGCTTTTTACAATCTTTTTGACAATGCAAGAGCCCATGGTGAACGTGTGACTGAGATT
AACATCCGTTTTCACACAGCCGGGGAAAATGTCGTAATTGAAGTAAAGGACAACGGAATAGGAATCTCTTCCGCTATGAA
AGAGCTTATTTTTGAAAAATCAGTTGGTAGAAACACCGGGCTTGGTCTTTTCCTTGTCAGGGGAATACTTTCCATTACAG
GCATGGAAATTGCCGAAACGGGAATCGAAGGCGAGGGCGCCAGATTTGAAATCAGGGTACCCCCCGGGAACTGGAGGATA
GTTCCGACAGAGTGCAGAGCCAGTTCCATAGAAGTATGCAATTGA

Upstream 100 bases:

>100_bases
TTTACTTTCACCTCCTTACTCTCCAAATTTACATATCCACAATTGAAAAAAGGAAGGTCGTCTTATCAGCCTGCAAATTC
ACACCACTGCGTTTCCCTTT

Downstream 100 bases:

>100_bases
AAGCATGAAAATAAAGCCCCAATCATGCAGCGTAAGTAATTTGCTTTTTTTTCTTTGATTTATATTTTTTATATACGTTT
CCCGGTATATTATAAAATAA

Product: sensory transduction protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 574; Mature: 573

Protein sequence:

>574_residues
MGALIFSGLISTLLAIRAYKAYNCHRSPFVKHFTLVMLGMTLWSINYAFEIGFMEPGQKYFFARLQYLGLSFIPVSWFLF
TSEYSGIGIQFARKYEKLLYLLPCSVILLMVTNNVHGLFFESFHLDYSREFPLLIIQHGSLFWIFYLYSFVLLVLGIFLL
FKQFVRLTAPYGTQAGIALTAACVPVLGNILHLADVGPFESLDPTPFSLAITGLILFWGTIQHEFLNIIPVARENVIESM
SDGYIVVDTSNSIVDVNRAVLELAGKTRKEVLGKNLTYLFGEGVELLCHTPEGDFGREISLKSGSEIKFFTVSVSPLMAR
NEPEGKLIMIHDITEIHRYQEALKQANKKINLMSNITRHDILNQVNVLSGYTELISEMLPLDVRGDPRIAKYFRNLNKGI
ETIHSQIIFTKDYQELGVVSPTWQSICSIAKEAAFAFSGQGIKFSIEDKGLEIYADPLLKKAFYNLFDNARAHGERVTEI
NIRFHTAGENVVIEVKDNGIGISSAMKELIFEKSVGRNTGLGLFLVRGILSITGMEIAETGIEGEGARFEIRVPPGNWRI
VPTECRASSIEVCN

Sequences:

>Translated_574_residues
MGALIFSGLISTLLAIRAYKAYNCHRSPFVKHFTLVMLGMTLWSINYAFEIGFMEPGQKYFFARLQYLGLSFIPVSWFLF
TSEYSGIGIQFARKYEKLLYLLPCSVILLMVTNNVHGLFFESFHLDYSREFPLLIIQHGSLFWIFYLYSFVLLVLGIFLL
FKQFVRLTAPYGTQAGIALTAACVPVLGNILHLADVGPFESLDPTPFSLAITGLILFWGTIQHEFLNIIPVARENVIESM
SDGYIVVDTSNSIVDVNRAVLELAGKTRKEVLGKNLTYLFGEGVELLCHTPEGDFGREISLKSGSEIKFFTVSVSPLMAR
NEPEGKLIMIHDITEIHRYQEALKQANKKINLMSNITRHDILNQVNVLSGYTELISEMLPLDVRGDPRIAKYFRNLNKGI
ETIHSQIIFTKDYQELGVVSPTWQSICSIAKEAAFAFSGQGIKFSIEDKGLEIYADPLLKKAFYNLFDNARAHGERVTEI
NIRFHTAGENVVIEVKDNGIGISSAMKELIFEKSVGRNTGLGLFLVRGILSITGMEIAETGIEGEGARFEIRVPPGNWRI
VPTECRASSIEVCN
>Mature_573_residues
GALIFSGLISTLLAIRAYKAYNCHRSPFVKHFTLVMLGMTLWSINYAFEIGFMEPGQKYFFARLQYLGLSFIPVSWFLFT
SEYSGIGIQFARKYEKLLYLLPCSVILLMVTNNVHGLFFESFHLDYSREFPLLIIQHGSLFWIFYLYSFVLLVLGIFLLF
KQFVRLTAPYGTQAGIALTAACVPVLGNILHLADVGPFESLDPTPFSLAITGLILFWGTIQHEFLNIIPVARENVIESMS
DGYIVVDTSNSIVDVNRAVLELAGKTRKEVLGKNLTYLFGEGVELLCHTPEGDFGREISLKSGSEIKFFTVSVSPLMARN
EPEGKLIMIHDITEIHRYQEALKQANKKINLMSNITRHDILNQVNVLSGYTELISEMLPLDVRGDPRIAKYFRNLNKGIE
TIHSQIIFTKDYQELGVVSPTWQSICSIAKEAAFAFSGQGIKFSIEDKGLEIYADPLLKKAFYNLFDNARAHGERVTEIN
IRFHTAGENVVIEVKDNGIGISSAMKELIFEKSVGRNTGLGLFLVRGILSITGMEIAETGIEGEGARFEIRVPPGNWRIV
PTECRASSIEVCN

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=368, Percent_Identity=24.4565217391304, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64417; Mature: 64286

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGALIFSGLISTLLAIRAYKAYNCHRSPFVKHFTLVMLGMTLWSINYAFEIGFMEPGQKY
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEEEEEECCCCCHHH
FFARLQYLGLSFIPVSWFLFTSEYSGIGIQFARKYEKLLYLLPCSVILLMVTNNVHGLFF
HHHHHHHHCCHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
ESFHLDYSREFPLLIIQHGSLFWIFYLYSFVLLVLGIFLLFKQFVRLTAPYGTQAGIALT
EEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
AACVPVLGNILHLADVGPFESLDPTPFSLAITGLILFWGTIQHEFLNIIPVARENVIESM
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SDGYIVVDTSNSIVDVNRAVLELAGKTRKEVLGKNLTYLFGEGVELLCHTPEGDFGREIS
CCCEEEEECCCCEEHHHHHHHHHHCCHHHHHHCCCCEEEECCCCEEEEECCCCCCCCEEE
LKSGSEIKFFTVSVSPLMARNEPEGKLIMIHDITEIHRYQEALKQANKKINLMSNITRHD
ECCCCEEEEEEEEECHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ILNQVNVLSGYTELISEMLPLDVRGDPRIAKYFRNLNKGIETIHSQIIFTKDYQELGVVS
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECHHHCCCCC
PTWQSICSIAKEAAFAFSGQGIKFSIEDKGLEIYADPLLKKAFYNLFDNARAHGERVTEI
CCHHHHHHHHHHHHHEECCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCCEEEEE
NIRFHTAGENVVIEVKDNGIGISSAMKELIFEKSVGRNTGLGLFLVRGILSITGMEIAET
EEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHC
GIEGEGARFEIRVPPGNWRIVPTECRASSIEVCN
CCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCC
>Mature Secondary Structure 
GALIFSGLISTLLAIRAYKAYNCHRSPFVKHFTLVMLGMTLWSINYAFEIGFMEPGQKY
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEEEEEECCCCCHHH
FFARLQYLGLSFIPVSWFLFTSEYSGIGIQFARKYEKLLYLLPCSVILLMVTNNVHGLFF
HHHHHHHHCCHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
ESFHLDYSREFPLLIIQHGSLFWIFYLYSFVLLVLGIFLLFKQFVRLTAPYGTQAGIALT
EEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
AACVPVLGNILHLADVGPFESLDPTPFSLAITGLILFWGTIQHEFLNIIPVARENVIESM
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SDGYIVVDTSNSIVDVNRAVLELAGKTRKEVLGKNLTYLFGEGVELLCHTPEGDFGREIS
CCCEEEEECCCCEEHHHHHHHHHHCCHHHHHHCCCCEEEECCCCEEEEECCCCCCCCEEE
LKSGSEIKFFTVSVSPLMARNEPEGKLIMIHDITEIHRYQEALKQANKKINLMSNITRHD
ECCCCEEEEEEEEECHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ILNQVNVLSGYTELISEMLPLDVRGDPRIAKYFRNLNKGIETIHSQIIFTKDYQELGVVS
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECHHHCCCCC
PTWQSICSIAKEAAFAFSGQGIKFSIEDKGLEIYADPLLKKAFYNLFDNARAHGERVTEI
CCHHHHHHHHHHHHHEECCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCCEEEEE
NIRFHTAGENVVIEVKDNGIGISSAMKELIFEKSVGRNTGLGLFLVRGILSITGMEIAET
EEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHC
GIEGEGARFEIRVPPGNWRIVPTECRASSIEVCN
CCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]