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The map label for this gene is rpoL

Identifier: 21227982

GI number: 21227982

Start: 2234475

End: 2234753

Strand: Direct

Name: rpoL

Synonym: MM_1880

Alternate gene names: 21227982

Gene position: 2234475-2234753 (Clockwise)

Preceding gene: 21227981

Following gene: 21227983

Centisome position: 54.55

GC content: 39.07

Gene sequence:

>279_bases
GTGGAACTGAACATTCTTAACAAAACAAATAATGAGCTTGAAGTCGAGCTTAGAGGCGAAACTCATACCCTTCTTAATCT
TCTTAAGGACCTCCTGATTAAAGATGAAAGGGTTGTAACGGCTTTTTACGATATGAAATATGTGAGCATCAGTGACCCTG
TCCTTTATATTAAAACCGATGGTGCGGATCCTATTCTGGTTTTAAAGGACGTGGTAGCAATCATTGTTTCTGAATGCGAC
GAATTTATCGATGTCTTCAGCAAAGCAGCAAATGCTTGA

Upstream 100 bases:

>100_bases
GGTAATTTCCTCTTCCTCTTACTTCAGGGATTTACGGCAGGTTAAAGATTTTACGGCATATTTATGACCGGTTAAATTCA
CCATTTACAGGTGGTCACCA

Downstream 100 bases:

>100_bases
AACTGAAGATCGCAGGACGTCTTTTTAAGGCGTTTTGCCCATTTCTTTCTTTCAGCAGGAAACATTAGAGAAATAAAGAT
CACTCAAAGATCATTCGTCC

Product: DNA-directed RNA polymerase subunit L

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 92; Mature: 92

Protein sequence:

>92_residues
MELNILNKTNNELEVELRGETHTLLNLLKDLLIKDERVVTAFYDMKYVSISDPVLYIKTDGADPILVLKDVVAIIVSECD
EFIDVFSKAANA

Sequences:

>Translated_92_residues
MELNILNKTNNELEVELRGETHTLLNLLKDLLIKDERVVTAFYDMKYVSISDPVLYIKTDGADPILVLKDVVAIIVSECD
EFIDVFSKAANA
>Mature_92_residues
MELNILNKTNNELEVELRGETHTLLNLLKDLLIKDERVVTAFYDMKYVSISDPVLYIKTDGADPILVLKDVVAIIVSECD
EFIDVFSKAANA

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG1761

COG function: function code K; DNA-directed RNA polymerase, subunit L

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal rpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOL_METMA (Q8PVT0)

Other databases:

- EMBL:   AE008384
- RefSeq:   NP_633904.1
- ProteinModelPortal:   Q8PVT0
- SMR:   Q8PVT0
- GeneID:   1480222
- GenomeReviews:   AE008384_GR
- KEGG:   mma:MM_1880
- NMPDR:   fig|192952.1.peg.1880
- HOGENOM:   HBG726964
- OMA:   HYLVEDE
- ProtClustDB:   PRK01146
- BioCyc:   MMAZ192952:MM1880-MONOMER
- BRENDA:   2.7.7.6
- HAMAP:   MF_00261
- InterPro:   IPR009025
- InterPro:   IPR008193
- InterPro:   IPR022905

Pfam domain/function: SSF55257 RNAP_RBP11-like

EC number: =2.7.7.6

Molecular weight: Translated: 10371; Mature: 10371

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: PS01154 RNA_POL_L_13KD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELNILNKTNNELEVELRGETHTLLNLLKDLLIKDERVVTAFYDMKYVSISDPVLYIKTD
CCEEECCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECEEEEEECCCEEEEEEC
GADPILVLKDVVAIIVSECDEFIDVFSKAANA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELNILNKTNNELEVELRGETHTLLNLLKDLLIKDERVVTAFYDMKYVSISDPVLYIKTD
CCEEECCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECEEEEEECCCEEEEEEC
GADPILVLKDVVAIIVSECDEFIDVFSKAANA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824