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The map label for this gene is prmA [C]

Identifier: 21227980

GI number: 21227980

Start: 2232533

End: 2233126

Strand: Direct

Name: prmA [C]

Synonym: MM_1878

Alternate gene names: 21227980

Gene position: 2232533-2233126 (Clockwise)

Preceding gene: 21227979

Following gene: 21227981

Centisome position: 54.5

GC content: 43.43

Gene sequence:

>594_bases
ATGAAACAGAGAAAACTTGAAATGCTGCTTGAGGAAATTGAAGGCTTTTCCGATCCTGAACTTGAACTGGAACAGTATCA
GACACCTTCTCTCCTTGCTGCTGAAGTTCTTCATTTCGCTTACATGCAGGGAGACCTTGATGATTCAGTCCATGACCTGG
GCTGCGGTACGGGAATCCTCGCAATAGGGGCAAAGGTTCTGGGAGCAAGGAAAGTTGTGGGGTATGATACTGACCCAAAA
GCTCTTGAGCTTGCAAGAAAAAATGCTGAAAAAATCGGAGTGGACGTTGAATTTATCTGTTCCGATATCTCTGAAGTCTC
GGAACGGGTAAAAACCACAATTATGAACCCTCCTTTTGGGGCAAGAGTTAAGGGAAGGGACAGACCCTTTCTTTCGTCAG
CATTAAGAACAAGTGAAGTAATATACTCCATCCACAACCGCGGAAGCCTTGCTTTTATCCAAAAGTTCATTAAGCCTGCG
GTCATTACACATTCGTACGTTGCGAAGTTCCCTATAAAGAGGACTTTTGACTTTCATCAAAAAGAAAGAGAGGTTATTGA
GGTAGAGATTTACAGAATTGCTGTTCATGCCTGA

Upstream 100 bases:

>100_bases
CTGAAGAACCTGTATGATTGGGAGTAAATGGCTGCATAATCATACATTCGTGGTCGAGCAATTCTAAAATTAAATCTAAT
AATACTAAAAGACAAAGGAT

Downstream 100 bases:

>100_bases
CCTGTATTCAGGGAACCTTTTAAGGCGTCATGTTTTACAGCTTATCTCTTTGTGCTTCATTCTGAAAGGCGGAATTAATA
AGCTTATTGAACAAAGAAAA

Product: methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MKQRKLEMLLEEIEGFSDPELELEQYQTPSLLAAEVLHFAYMQGDLDDSVHDLGCGTGILAIGAKVLGARKVVGYDTDPK
ALELARKNAEKIGVDVEFICSDISEVSERVKTTIMNPPFGARVKGRDRPFLSSALRTSEVIYSIHNRGSLAFIQKFIKPA
VITHSYVAKFPIKRTFDFHQKEREVIEVEIYRIAVHA

Sequences:

>Translated_197_residues
MKQRKLEMLLEEIEGFSDPELELEQYQTPSLLAAEVLHFAYMQGDLDDSVHDLGCGTGILAIGAKVLGARKVVGYDTDPK
ALELARKNAEKIGVDVEFICSDISEVSERVKTTIMNPPFGARVKGRDRPFLSSALRTSEVIYSIHNRGSLAFIQKFIKPA
VITHSYVAKFPIKRTFDFHQKEREVIEVEIYRIAVHA
>Mature_197_residues
MKQRKLEMLLEEIEGFSDPELELEQYQTPSLLAAEVLHFAYMQGDLDDSVHDLGCGTGILAIGAKVLGARKVVGYDTDPK
ALELARKNAEKIGVDVEFICSDISEVSERVKTTIMNPPFGARVKGRDRPFLSSALRTSEVIYSIHNRGSLAFIQKFIKPA
VITHSYVAKFPIKRTFDFHQKEREVIEVEIYRIAVHA

Specific function: Methylates Ribosomal Protein L11. [C]

COG id: COG2263

COG function: function code J; Predicted RNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI92859575, Length=205, Percent_Identity=34.6341463414634, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17552558, Length=212, Percent_Identity=26.4150943396226, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI221512926, Length=209, Percent_Identity=34.4497607655502, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28574609, Length=209, Percent_Identity=34.4497607655502, Blast_Score=113, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 22166; Mature: 22166

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRKLEMLLEEIEGFSDPELELEQYQTPSLLAAEVLHFAYMQGDLDDSVHDLGCGTGIL
CCHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHH
AIGAKVLGARKVVGYDTDPKALELARKNAEKIGVDVEFICSDISEVSERVKTTIMNPPFG
HHHHHHHCCHHEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCC
ARVKGRDRPFLSSALRTSEVIYSIHNRGSLAFIQKFIKPAVITHSYVAKFPIKRTFDFHQ
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KEREVIEVEIYRIAVHA
HHHHHHEEEEEEEEECC
>Mature Secondary Structure
MKQRKLEMLLEEIEGFSDPELELEQYQTPSLLAAEVLHFAYMQGDLDDSVHDLGCGTGIL
CCHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHH
AIGAKVLGARKVVGYDTDPKALELARKNAEKIGVDVEFICSDISEVSERVKTTIMNPPFG
HHHHHHHCCHHEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCC
ARVKGRDRPFLSSALRTSEVIYSIHNRGSLAFIQKFIKPAVITHSYVAKFPIKRTFDFHQ
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KEREVIEVEIYRIAVHA
HHHHHHEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]