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The map label for this gene is pelA [H]

Identifier: 21227917

GI number: 21227917

Start: 2164907

End: 2165959

Strand: Direct

Name: pelA [H]

Synonym: MM_1815

Alternate gene names: 21227917

Gene position: 2164907-2165959 (Clockwise)

Preceding gene: 21227916

Following gene: 21227918

Centisome position: 52.85

GC content: 48.81

Gene sequence:

>1053_bases
ATGAGGGTTACAAACCGTTCTCTAAAAGGCCGGGAAGGGGAAATTGCCGTAACAGCCGAGACTCTTGACGATCTCTGGCA
CCTGAAGTATATTATTGAAAAAGGTGACATGGTCTTTGCTCTGACCAGAAGGAAAGCCGATTCTGCAAGCGACAAACTCC
GCCCGGAAAAGGTTGAGAAGGTAAAGGTAAGGCTGGGGATAAGGGTTGAAGAACTGGAGTTCCATAAATTTGCAAACAGG
CTGAGAATACACGGGCCGATTGAGCACGGAATGGACACAGGCTCCTATCACACACTCAATGTGGAAATAGGGACCAATAT
TTCCATCATTAAGGAGCACTGGAAGAACGACCAGCTCCAGCGCATTCAGGACGCCGAAGAAGCAGGAAAGCGCCCAAAAG
TTGTTATTGTAGCGGTTGAGGAGGGTGACGCAGATATCGGGTTTGTGCGCCACTATGGAATCGAAGTCTATTCTCATATC
AGGCAGTCCTCCGGGAAGCGGGAGACCGGGCTCAGGAATGAGTTTTTCAGGGAAATTGTTGAACAGCTCAGGCACGCAGT
TCCTGAAGACGCTTCCATAGTGATTGCAGGGCCCGGTTTCACCAAAGAAGATTTCCTGAAATATTTTAATGAAACTGAGT
CTGAAATGGCTTCTAAGGCATTGACTGAAGATACGTCCATGATAGGTATGTCCGGGTTTCAGGAGGTGCTCCGCAGAGGA
GCGGTGGACCGGATCATGCAGGAGTCCCGAATAGCCCGGGAATCCTCTCTCATGGAAGACCTTATCAGGGAAATCTCTAT
GGACGGAAAAGCAGCTTACGGTTTTGCAGATGTGAAAAATGCTCTTGGTTACGGGGCTGTTGAAACCCTGCTCATAGCTG
ACGAAACGCTGCGTGAAGGGCGGGAAAAAGGTGAGGATATAGATAAACTACTTATGGAGGTCGAACAGGCTCAGGGAAAA
GTTGTTGTGTTCAGCACGGCCTTTGAGCCCGGAGAAAAACTTCACAAACTTGGAGGAATTGCAGCTTTGCTCCGTTTCAA
AGTAACAGGCTGA

Upstream 100 bases:

>100_bases
AATTTGCAGAAGAAATAGGGGAAGGCAGTGAAGTAAAAGTTAAAGCTGAAGCCAGAGAGGGAAATGAAGAAATAATTGAA
ATACGCGGAGTGAAAAAGGA

Downstream 100 bases:

>100_bases
CCCTGTGCAGACCTGTTAAGACCCTGTGCAGACCTGTTAAGATCCTGTGCAGGCCTGTTAATATTCAGCCGTTAACTGTC
TATTATTTACTTAAATTTTC

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MRVTNRSLKGREGEIAVTAETLDDLWHLKYIIEKGDMVFALTRRKADSASDKLRPEKVEKVKVRLGIRVEELEFHKFANR
LRIHGPIEHGMDTGSYHTLNVEIGTNISIIKEHWKNDQLQRIQDAEEAGKRPKVVIVAVEEGDADIGFVRHYGIEVYSHI
RQSSGKRETGLRNEFFREIVEQLRHAVPEDASIVIAGPGFTKEDFLKYFNETESEMASKALTEDTSMIGMSGFQEVLRRG
AVDRIMQESRIARESSLMEDLIREISMDGKAAYGFADVKNALGYGAVETLLIADETLREGREKGEDIDKLLMEVEQAQGK
VVVFSTAFEPGEKLHKLGGIAALLRFKVTG

Sequences:

>Translated_350_residues
MRVTNRSLKGREGEIAVTAETLDDLWHLKYIIEKGDMVFALTRRKADSASDKLRPEKVEKVKVRLGIRVEELEFHKFANR
LRIHGPIEHGMDTGSYHTLNVEIGTNISIIKEHWKNDQLQRIQDAEEAGKRPKVVIVAVEEGDADIGFVRHYGIEVYSHI
RQSSGKRETGLRNEFFREIVEQLRHAVPEDASIVIAGPGFTKEDFLKYFNETESEMASKALTEDTSMIGMSGFQEVLRRG
AVDRIMQESRIARESSLMEDLIREISMDGKAAYGFADVKNALGYGAVETLLIADETLREGREKGEDIDKLLMEVEQAQGK
VVVFSTAFEPGEKLHKLGGIAALLRFKVTG
>Mature_350_residues
MRVTNRSLKGREGEIAVTAETLDDLWHLKYIIEKGDMVFALTRRKADSASDKLRPEKVEKVKVRLGIRVEELEFHKFANR
LRIHGPIEHGMDTGSYHTLNVEIGTNISIIKEHWKNDQLQRIQDAEEAGKRPKVVIVAVEEGDADIGFVRHYGIEVYSHI
RQSSGKRETGLRNEFFREIVEQLRHAVPEDASIVIAGPGFTKEDFLKYFNETESEMASKALTEDTSMIGMSGFQEVLRRG
AVDRIMQESRIARESSLMEDLIREISMDGKAAYGFADVKNALGYGAVETLLIADETLREGREKGEDIDKLLMEVEQAQGK
VVVFSTAFEPGEKLHKLGGIAALLRFKVTG

Specific function: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has end

COG id: COG1537

COG function: function code R; Predicted RNA-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eukaryotic release factor 1 family. Pelota subfamily [H]

Homologues:

Organism=Homo sapiens, GI31880783, Length=376, Percent_Identity=25.531914893617, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17554648, Length=363, Percent_Identity=26.4462809917355, Blast_Score=98, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6324327, Length=363, Percent_Identity=24.7933884297521, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI17136914, Length=367, Percent_Identity=29.1553133514986, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005140
- InterPro:   IPR005141
- InterPro:   IPR005142
- InterPro:   IPR004405 [H]

Pfam domain/function: PF03463 eRF1_1; PF03464 eRF1_2; PF03465 eRF1_3 [H]

EC number: NA

Molecular weight: Translated: 39447; Mature: 39447

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVTNRSLKGREGEIAVTAETLDDLWHLKYIIEKGDMVFALTRRKADSASDKLRPEKVEK
CCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHCCCHHHHHH
VKVRLGIRVEELEFHKFANRLRIHGPIEHGMDTGSYHTLNVEIGTNISIIKEHWKNDQLQ
HHHHHCCCHHHHHHHHHHHHEEECCCHHHCCCCCCEEEEEEEECCCHHHHHHHHCCCHHH
RIQDAEEAGKRPKVVIVAVEEGDADIGFVRHYGIEVYSHIRQSSGKRETGLRNEFFREIV
HHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
EQLRHAVPEDASIVIAGPGFTKEDFLKYFNETESEMASKALTEDTSMIGMSGFQEVLRRG
HHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVDRIMQESRIARESSLMEDLIREISMDGKAAYGFADVKNALGYGAVETLLIADETLREG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
REKGEDIDKLLMEVEQAQGKVVVFSTAFEPGEKLHKLGGIAALLRFKVTG
HHCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHEEECC
>Mature Secondary Structure
MRVTNRSLKGREGEIAVTAETLDDLWHLKYIIEKGDMVFALTRRKADSASDKLRPEKVEK
CCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHCCCHHHHHH
VKVRLGIRVEELEFHKFANRLRIHGPIEHGMDTGSYHTLNVEIGTNISIIKEHWKNDQLQ
HHHHHCCCHHHHHHHHHHHHEEECCCHHHCCCCCCEEEEEEEECCCHHHHHHHHCCCHHH
RIQDAEEAGKRPKVVIVAVEEGDADIGFVRHYGIEVYSHIRQSSGKRETGLRNEFFREIV
HHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
EQLRHAVPEDASIVIAGPGFTKEDFLKYFNETESEMASKALTEDTSMIGMSGFQEVLRRG
HHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVDRIMQESRIARESSLMEDLIREISMDGKAAYGFADVKNALGYGAVETLLIADETLREG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
REKGEDIDKLLMEVEQAQGKVVVFSTAFEPGEKLHKLGGIAALLRFKVTG
HHCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]