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The map label for this gene is 21227801

Identifier: 21227801

GI number: 21227801

Start: 2041751

End: 2042236

Strand: Reverse

Name: 21227801

Synonym: MM_1699

Alternate gene names: NA

Gene position: 2042236-2041751 (Counterclockwise)

Preceding gene: 21227802

Following gene: 21227800

Centisome position: 49.86

GC content: 45.68

Gene sequence:

>486_bases
GTGTACAGTAAGGAATCCTGTGAGAGGTGTGAAGAAATGGAAAAAATAATACCTTCGGGACAGGGTAAAAAAAGTATCTT
CCTTTCGGGATCCATAAGGGGAGGAAGACAGCTGCTTGAAACATACAGGTTCATATATGATGCTCTTGAAGAAGCAGGTG
CGGAAGTGCTCAGCTGGCATGTTGCAGACCCGGAACTGGAAAAAACAGAATCAAAAATGACTGAGCAGGAGATTTATGCC
AGAGACCTCGGTTTGCTTGAAAAAAGTGATGCACTGATTGCAGAGGTAACTGTGCCGTCCACTGGCGTTGGGTATGAAAT
ATGCAGGGCGCTTGTCCGAAAAATTCCCGTACTCTGCCTTCACATGCCAGATGTGGCAGTTTCATCAATGGTGCTGGGGA
ACCCTGATACTCTGATGGAAGTCCGGTCCTATCCAGATAAGGAGGCACTTAAAGAGATTATTATTGATTTTATCCGGGCT
CTCTGA

Upstream 100 bases:

>100_bases
TACAGAAAAGCCGTTGACGCATATTATAAGTCAGGAGAAAAGACAAAGGAAAAATGTGAAGGCCTCGGAAAGGGTTTTAC
CACAGGACACTATTTCAGAG

Downstream 100 bases:

>100_bases
AGAAAAATGCGCCATAAAATACATTATGTTCATCAAATAAAAGAGATCGGATGGCATTTTCAAGTACTTCTGGCACAATT
TTTTTAAAAGCCCTGACTGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MYSKESCERCEEMEKIIPSGQGKKSIFLSGSIRGGRQLLETYRFIYDALEEAGAEVLSWHVADPELEKTESKMTEQEIYA
RDLGLLEKSDALIAEVTVPSTGVGYEICRALVRKIPVLCLHMPDVAVSSMVLGNPDTLMEVRSYPDKEALKEIIIDFIRA
L

Sequences:

>Translated_161_residues
MYSKESCERCEEMEKIIPSGQGKKSIFLSGSIRGGRQLLETYRFIYDALEEAGAEVLSWHVADPELEKTESKMTEQEIYA
RDLGLLEKSDALIAEVTVPSTGVGYEICRALVRKIPVLCLHMPDVAVSSMVLGNPDTLMEVRSYPDKEALKEIIIDFIRA
L
>Mature_161_residues
MYSKESCERCEEMEKIIPSGQGKKSIFLSGSIRGGRQLLETYRFIYDALEEAGAEVLSWHVADPELEKTESKMTEQEIYA
RDLGLLEKSDALIAEVTVPSTGVGYEICRALVRKIPVLCLHMPDVAVSSMVLGNPDTLMEVRSYPDKEALKEIIIDFIRA
L

Specific function: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5- phosphate and a purine or pyrimidine base

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoxyribonucleoside 5'-monophosphate N- glycosidase family

Homologues:

Organism=Homo sapiens, GI5454002, Length=145, Percent_Identity=36.551724137931, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI40354201, Length=118, Percent_Identity=38.9830508474576, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RCL_METMA (Q8PW97)

Other databases:

- EMBL:   AE008384
- RefSeq:   NP_633723.1
- ProteinModelPortal:   Q8PW97
- GeneID:   1480041
- GenomeReviews:   AE008384_GR
- KEGG:   mma:MM_1699
- NMPDR:   fig|192952.1.peg.1699
- HOGENOM:   HBG540497
- OMA:   VLSWHVA
- ProtClustDB:   CLSK568747
- BioCyc:   MMAZ192952:MM1699-MONOMER
- GO:   GO:0005634
- InterPro:   IPR007710

Pfam domain/function: PF05014 Nuc_deoxyrib_tr

EC number: NA

Molecular weight: Translated: 18044; Mature: 18044

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: BINDING 42-42 BINDING 106-106

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSKESCERCEEMEKIIPSGQGKKSIFLSGSIRGGRQLLETYRFIYDALEEAGAEVLSWH
CCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
VADPELEKTESKMTEQEIYARDLGLLEKSDALIAEVTVPSTGVGYEICRALVRKIPVLCL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
HMPDVAVSSMVLGNPDTLMEVRSYPDKEALKEIIIDFIRAL
CCCHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHC
>Mature Secondary Structure
MYSKESCERCEEMEKIIPSGQGKKSIFLSGSIRGGRQLLETYRFIYDALEEAGAEVLSWH
CCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
VADPELEKTESKMTEQEIYARDLGLLEKSDALIAEVTVPSTGVGYEICRALVRKIPVLCL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
HMPDVAVSSMVLGNPDTLMEVRSYPDKEALKEIIIDFIRAL
CCCHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824