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The map label for this gene is hdrD [H]

Identifier: 21227788

GI number: 21227788

Start: 2028602

End: 2029750

Strand: Direct

Name: hdrD [H]

Synonym: MM_1686

Alternate gene names: 21227788

Gene position: 2028602-2029750 (Clockwise)

Preceding gene: 21227780

Following gene: 21227789

Centisome position: 49.52

GC content: 47.87

Gene sequence:

>1149_bases
ATGAATATAGTAGAAGAACACAGGGAAAAATGTACGAGATGCGGGCAGTGTCTCGAGGTCTGCTCCCGGTATGAAGACCT
TGGTGTGCTTGACCGGCTTTACGGGTATCTTGATGGATCATCAAATATCGATTCCGAGTCCCTGCTGCGCTGCCTTACAT
GCGGGCTCTGCATTTCTGCCTGCCCTGAAAACCTCGGGATCAAGCCTCTGATATCTCCTTCCCGACAGAAATGGATAAAT
GAAAACGGCCTTTCTGAGAGGCAGACCATGGTGGATCCCGAGTCTGAGAATAACCTATTCAAAAAAATTTCTGAAATGGA
TGAGATCCCGGAGTATATAGACAGGCCCGGATCGGTGGTATATTTTCCGGGCTGCGCTGGCACCTATATCAACAAAGTAA
TGGCTCAGGCTTCTGTGGCTCTTCTGGAAAAAGCCGGGGTTGATTATACTGTCCTGAGCGGTCTTGAATACTGCTGCGGG
GCTGTATCCGCAGGTGCAGGAGACCAGGGCCCTATCTGCAAGCATGGGCAGAAAAATATTGACGAAATCAGGAAAAGAGG
GGCAAAAGTCCTTATCACTGCCTGCCCCGGGTGTTTCAAAGCTTTTAAAGATATTTATCCACGCATGTTTGGAAAACTGG
ACTTTGAAGTTCTGCAGGTCTCTCAGTACCTTGACCGGCTTTTAAAAGAAGGCAGGCTTACTCCGGAAAACGCTCTTAAA
TTCCGGGTTTTTTACCATGACCCATGCCACCTGACAAGAGGGATGGGAGTCTACACGGAAGCAAGGGATGTGCTTGAAAA
GATTCCGGGGACAGGGCTGGCAAATAAAACTCCGGAAGGTTCGGCTTGCTGTGGCTTCGGGGGAGGAGTAAGGGTAAATT
ATCCTTCAGAATCTATTTCCGTAGCTTCTGACAGGTTCCGGGCTGCTGAAAAACTGGGCTGCGACGCGATTATAACAAAC
TGCGGCGGCTGTATGCAGAACCTTGCCGAAGCCGGAAAAAATGAGAAAATAAAGATCTTTGATCTTGCTGAGTATCTTGC
CCTTGCTTGCGGAATAAAAATAGAAAGAGAAGACCGGAGAATGATAGAGCTTGTAAACAGGGCTTACAATTTATGTGTTC
CGGGATACAAAGAACCGGACCTTTCATAA

Upstream 100 bases:

>100_bases
CGGTTCAATGACCTGCAGGGGTAGAATTCTTCAGAAAGAGGTTTTAAGGATCGATATGAGAATAAAGTCGCATGAGTTTA
AAATGATATGGAGTTAAAAT

Downstream 100 bases:

>100_bases
ATATGGGGTCCTAACCTCTTTTTGCCCTTACATGAAATCTTTATCCTTTTTTACCTTTCTTTTGTTTTTTGCATTCCGCT
CCACGAATTTCAAATTATCG

Product: Iron-sulfur binding reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MNIVEEHREKCTRCGQCLEVCSRYEDLGVLDRLYGYLDGSSNIDSESLLRCLTCGLCISACPENLGIKPLISPSRQKWIN
ENGLSERQTMVDPESENNLFKKISEMDEIPEYIDRPGSVVYFPGCAGTYINKVMAQASVALLEKAGVDYTVLSGLEYCCG
AVSAGAGDQGPICKHGQKNIDEIRKRGAKVLITACPGCFKAFKDIYPRMFGKLDFEVLQVSQYLDRLLKEGRLTPENALK
FRVFYHDPCHLTRGMGVYTEARDVLEKIPGTGLANKTPEGSACCGFGGGVRVNYPSESISVASDRFRAAEKLGCDAIITN
CGGCMQNLAEAGKNEKIKIFDLAEYLALACGIKIEREDRRMIELVNRAYNLCVPGYKEPDLS

Sequences:

>Translated_382_residues
MNIVEEHREKCTRCGQCLEVCSRYEDLGVLDRLYGYLDGSSNIDSESLLRCLTCGLCISACPENLGIKPLISPSRQKWIN
ENGLSERQTMVDPESENNLFKKISEMDEIPEYIDRPGSVVYFPGCAGTYINKVMAQASVALLEKAGVDYTVLSGLEYCCG
AVSAGAGDQGPICKHGQKNIDEIRKRGAKVLITACPGCFKAFKDIYPRMFGKLDFEVLQVSQYLDRLLKEGRLTPENALK
FRVFYHDPCHLTRGMGVYTEARDVLEKIPGTGLANKTPEGSACCGFGGGVRVNYPSESISVASDRFRAAEKLGCDAIITN
CGGCMQNLAEAGKNEKIKIFDLAEYLALACGIKIEREDRRMIELVNRAYNLCVPGYKEPDLS
>Mature_382_residues
MNIVEEHREKCTRCGQCLEVCSRYEDLGVLDRLYGYLDGSSNIDSESLLRCLTCGLCISACPENLGIKPLISPSRQKWIN
ENGLSERQTMVDPESENNLFKKISEMDEIPEYIDRPGSVVYFPGCAGTYINKVMAQASVALLEKAGVDYTVLSGLEYCCG
AVSAGAGDQGPICKHGQKNIDEIRKRGAKVLITACPGCFKAFKDIYPRMFGKLDFEVLQVSQYLDRLLKEGRLTPENALK
FRVFYHDPCHLTRGMGVYTEARDVLEKIPGTGLANKTPEGSACCGFGGGVRVNYPSESISVASDRFRAAEKLGCDAIITN
CGGCMQNLAEAGKNEKIKIFDLAEYLALACGIKIEREDRRMIELVNRAYNLCVPGYKEPDLS

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Loosely Bound To The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1788576, Length=271, Percent_Identity=27.6752767527675, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR004017
- InterPro:   IPR012285
- InterPro:   IPR009051 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 42149; Mature: 42149

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
5.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVEEHREKCTRCGQCLEVCSRYEDLGVLDRLYGYLDGSSNIDSESLLRCLTCGLCISA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
CPENLGIKPLISPSRQKWINENGLSERQTMVDPESENNLFKKISEMDEIPEYIDRPGSVV
CCCCCCCCCCCCCHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
YFPGCAGTYINKVMAQASVALLEKAGVDYTVLSGLEYCCGAVSAGAGDQGPICKHGQKNI
EECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
DEIRKRGAKVLITACPGCFKAFKDIYPRMFGKLDFEVLQVSQYLDRLLKEGRLTPENALK
HHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCEE
FRVFYHDPCHLTRGMGVYTEARDVLEKIPGTGLANKTPEGSACCGFGGGVRVNYPSESIS
EEEEEECCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHH
VASDRFRAAEKLGCDAIITNCGGCMQNLAEAGKNEKIKIFDLAEYLALACGIKIEREDRR
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCCCCHHHHH
MIELVNRAYNLCVPGYKEPDLS
HHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNIVEEHREKCTRCGQCLEVCSRYEDLGVLDRLYGYLDGSSNIDSESLLRCLTCGLCISA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
CPENLGIKPLISPSRQKWINENGLSERQTMVDPESENNLFKKISEMDEIPEYIDRPGSVV
CCCCCCCCCCCCCHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
YFPGCAGTYINKVMAQASVALLEKAGVDYTVLSGLEYCCGAVSAGAGDQGPICKHGQKNI
EECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
DEIRKRGAKVLITACPGCFKAFKDIYPRMFGKLDFEVLQVSQYLDRLLKEGRLTPENALK
HHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCEE
FRVFYHDPCHLTRGMGVYTEARDVLEKIPGTGLANKTPEGSACCGFGGGVRVNYPSESIS
EEEEEECCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHH
VASDRFRAAEKLGCDAIITNCGGCMQNLAEAGKNEKIKIFDLAEYLALACGIKIEREDRR
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCCCCHHHHH
MIELVNRAYNLCVPGYKEPDLS
HHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]