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The map label for this gene is zupT [H]

Identifier: 21227701

GI number: 21227701

Start: 1902064

End: 1902831

Strand: Direct

Name: zupT [H]

Synonym: MM_1599

Alternate gene names: 21227701

Gene position: 1902064-1902831 (Clockwise)

Preceding gene: 21227700

Following gene: 21227703

Centisome position: 46.43

GC content: 45.05

Gene sequence:

>768_bases
ATGGGAGATGTCACAACTGCTTTTATTCTCACAACATGTGCAGGACTCTCAACCGGTACTGGCAGTCTCATAGCTTTTTT
GGTTCCCAATCTAAAGTTTACCTGGCTGTCCATGCTGCTTGGTTTTGCTGCGGGGGCAATGATCTATATCTCATTTGTAG
ATTTACTTGCTGAATCTGTTGGTGCAGTTGGTTTTTTCCAGGCAAATGCTGCTTTTTTTCTGGGGATGCTGGGGATGGGA
ATTCTTGACCGCGTGATAGAGCACATTCATACGGATACTCTCCCTGATAGAAACACTCTTTCCCGGAGTGAAGAGAATGA
CCTTCAAAAAGCCGGCCTGCTGACTGCAGCAGGAATTGCCATGCACAACTTCCCTGAAGGAATTGCAGTGTTAGCTGCGT
CCCTGGGTTCTCCTTATCTGGGGTTTTCGGTTGCTCTGGCCATAGCAATCCATAACATCCCTGAAGGAATTGCAGTTTCG
GTTCCTATCTATTATGCCAGTGGTGACCGAAAAAAAGCGTTTGCTTATTCTTTCTTTGCAGGGCTTACCGAACCTCTGGG
AGCTGTGTTTGCATATTTTTTTCTTTTCCGCTTTCTATCTCCTGAAATGCTTTTCCTTATGCTCGCTGCGGTCGGAGGGG
TAATGGTCTTTATATGTTTTGATGAACTGCTGCCGATCTCCATAAAATATGGAAACGAGCATCTGACTTTTCTGGGGGTA
TTTTCTGGAATGTCTGTTATCGCTCTGAGCCTTTATCTTATACATTGA

Upstream 100 bases:

>100_bases
ATATTTATTAATTTACTTTATATAAAACTCTCCCGTATTTGTCTTTTCTTTTTCTATGAATTTAAATCCTATCCCGTATT
TTATTTATTGGGGGAGCTAA

Downstream 100 bases:

>100_bases
AATTTTTGAGGCTTTTTTCCCAAAAGCTAACAATCATTATCCAAAAGCTGCATTTTATGTATCATTTCCCTTATCTCTCG
ATTGTTAAATTTTCAACTGG

Product: zinc transporter ZupT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MGDVTTAFILTTCAGLSTGTGSLIAFLVPNLKFTWLSMLLGFAAGAMIYISFVDLLAESVGAVGFFQANAAFFLGMLGMG
ILDRVIEHIHTDTLPDRNTLSRSEENDLQKAGLLTAAGIAMHNFPEGIAVLAASLGSPYLGFSVALAIAIHNIPEGIAVS
VPIYYASGDRKKAFAYSFFAGLTEPLGAVFAYFFLFRFLSPEMLFLMLAAVGGVMVFICFDELLPISIKYGNEHLTFLGV
FSGMSVIALSLYLIH

Sequences:

>Translated_255_residues
MGDVTTAFILTTCAGLSTGTGSLIAFLVPNLKFTWLSMLLGFAAGAMIYISFVDLLAESVGAVGFFQANAAFFLGMLGMG
ILDRVIEHIHTDTLPDRNTLSRSEENDLQKAGLLTAAGIAMHNFPEGIAVLAASLGSPYLGFSVALAIAIHNIPEGIAVS
VPIYYASGDRKKAFAYSFFAGLTEPLGAVFAYFFLFRFLSPEMLFLMLAAVGGVMVFICFDELLPISIKYGNEHLTFLGV
FSGMSVIALSLYLIH
>Mature_254_residues
GDVTTAFILTTCAGLSTGTGSLIAFLVPNLKFTWLSMLLGFAAGAMIYISFVDLLAESVGAVGFFQANAAFFLGMLGMGI
LDRVIEHIHTDTLPDRNTLSRSEENDLQKAGLLTAAGIAMHNFPEGIAVLAASLGSPYLGFSVALAIAIHNIPEGIAVSV
PIYYASGDRKKAFAYSFFAGLTEPLGAVFAYFFLFRFLSPEMLFLMLAAVGGVMVFICFDELLPISIKYGNEHLTFLGVF
SGMSVIALSLYLIH

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI229577422, Length=152, Percent_Identity=32.8947368421053, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI229577418, Length=152, Percent_Identity=32.8947368421053, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1789419, Length=254, Percent_Identity=35.8267716535433, Blast_Score=146, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17507805, Length=248, Percent_Identity=27.8225806451613, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24652846, Length=164, Percent_Identity=31.7073170731707, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 27267; Mature: 27136

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDVTTAFILTTCAGLSTGTGSLIAFLVPNLKFTWLSMLLGFAAGAMIYISFVDLLAESV
CCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAVGFFQANAAFFLGMLGMGILDRVIEHIHTDTLPDRNTLSRSEENDLQKAGLLTAAGIA
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHHHH
MHNFPEGIAVLAASLGSPYLGFSVALAIAIHNIPEGIAVSVPIYYASGDRKKAFAYSFFA
HHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHH
GLTEPLGAVFAYFFLFRFLSPEMLFLMLAAVGGVMVFICFDELLPISIKYGNEHLTFLGV
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCEEEEHHH
FSGMSVIALSLYLIH
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
GDVTTAFILTTCAGLSTGTGSLIAFLVPNLKFTWLSMLLGFAAGAMIYISFVDLLAESV
CCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAVGFFQANAAFFLGMLGMGILDRVIEHIHTDTLPDRNTLSRSEENDLQKAGLLTAAGIA
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHHHH
MHNFPEGIAVLAASLGSPYLGFSVALAIAIHNIPEGIAVSVPIYYASGDRKKAFAYSFFA
HHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHH
GLTEPLGAVFAYFFLFRFLSPEMLFLMLAAVGGVMVFICFDELLPISIKYGNEHLTFLGV
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCEEEEHHH
FSGMSVIALSLYLIH
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]