Click here to switch to the map view.

The map label for this gene is mdaB [C]

Identifier: 21227683

GI number: 21227683

Start: 1882528

End: 1883169

Strand: Reverse

Name: mdaB [C]

Synonym: MM_1581

Alternate gene names: 21227683

Gene position: 1883169-1882528 (Counterclockwise)

Preceding gene: 21227684

Following gene: 21227682

Centisome position: 45.97

GC content: 43.3

Gene sequence:

>642_bases
ATGAAAGTCCTTTATATCTTTGCACACCCTGAGCCGAAGTCCTTTAACGCTGCTATGAAAGATACAGCTATTGCTGCCCT
GAAGGATAAAGGGCACGAAGTAAAGCTCTCCGACCTTTACGCGATGGAATTTAACCCTGTGCTGAAAGCCTCGGACTTTA
CTGAGAGAAAAAACCCGGATATTTTTAATGCTTTCCTCGAAGCTATCAAAGCCTCAAAAACCGGGGCTTTTTCATCCGAC
ATAAAAGAGGAGATGGAAAAAGTAAAATGGGCTGACCTGTTGGCATTTCAGTTCCCAATTTACTTTACATCCATGCCAGC
AATAATGAAAGGCTGGATTGACCGTGTACTGGCTCCGGGGTTTGGCTTTAATCCCATAACCAGCAGTGCCTATGACACCG
GACTCCTTAAAGGAAAAGCAGCAATGCTTGCATTTACTACCGGCGCTCCGAAAGAAATGTATTCTGAGGGTGGAGCTCAT
GGCGATATTCACAGGCATCTTGAATCCATAACTCACTGTGTTTTTGAATATATGGGAATGAAAGTGCTGCCATCCTTCAT
AGTTTATGAAGCCAGTGCCATGAAACAGGAAAAGGGAATTGAAGAACTGGAGAGATATAAAAAGAGGATTTCCGAACTAT
AA

Upstream 100 bases:

>100_bases
GAATAAATTAACAGAAGAATGCATAACTTAACAGGGGAGGCAGCCTTACATATTTATTCAGGGAAACGAATTTCATGGAT
AGAATAAAGGGGGAAATAAA

Downstream 100 bases:

>100_bases
ATAGAAAAGAAAACGCCTTTTTTTAATTTTTTAATTTTTCGGGGAACTGTGGGGCAGCCTGAATCATATCTGAGTCTTAT
ACTACTGGATAATAATATTT

Product: putative NAD(P)H oxidoreductase

Products: NAD+; NADP+; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MKVLYIFAHPEPKSFNAAMKDTAIAALKDKGHEVKLSDLYAMEFNPVLKASDFTERKNPDIFNAFLEAIKASKTGAFSSD
IKEEMEKVKWADLLAFQFPIYFTSMPAIMKGWIDRVLAPGFGFNPITSSAYDTGLLKGKAAMLAFTTGAPKEMYSEGGAH
GDIHRHLESITHCVFEYMGMKVLPSFIVYEASAMKQEKGIEELERYKKRISEL

Sequences:

>Translated_213_residues
MKVLYIFAHPEPKSFNAAMKDTAIAALKDKGHEVKLSDLYAMEFNPVLKASDFTERKNPDIFNAFLEAIKASKTGAFSSD
IKEEMEKVKWADLLAFQFPIYFTSMPAIMKGWIDRVLAPGFGFNPITSSAYDTGLLKGKAAMLAFTTGAPKEMYSEGGAH
GDIHRHLESITHCVFEYMGMKVLPSFIVYEASAMKQEKGIEELERYKKRISEL
>Mature_213_residues
MKVLYIFAHPEPKSFNAAMKDTAIAALKDKGHEVKLSDLYAMEFNPVLKASDFTERKNPDIFNAFLEAIKASKTGAFSSD
IKEEMEKVKWADLLAFQFPIYFTSMPAIMKGWIDRVLAPGFGFNPITSSAYDTGLLKGKAAMLAFTTGAPKEMYSEGGAH
GDIHRHLESITHCVFEYMGMKVLPSFIVYEASAMKQEKGIEELERYKKRISEL

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=202, Percent_Identity=43.5643564356436, Blast_Score=168, Evalue=3e-42,
Organism=Homo sapiens, GI4505415, Length=213, Percent_Identity=40.3755868544601, Blast_Score=134, Evalue=9e-32,
Organism=Homo sapiens, GI70995396, Length=163, Percent_Identity=41.7177914110429, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI70995422, Length=213, Percent_Identity=33.8028169014084, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.2

Molecular weight: Translated: 23911; Mature: 23911

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLYIFAHPEPKSFNAAMKDTAIAALKDKGHEVKLSDLYAMEFNPVLKASDFTERKNPD
CEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEHHHEEEEECCCCCCCCCCCCCCCCH
IFNAFLEAIKASKTGAFSSDIKEEMEKVKWADLLAFQFPIYFTSMPAIMKGWIDRVLAPG
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FGFNPITSSAYDTGLLKGKAAMLAFTTGAPKEMYSEGGAHGDIHRHLESITHCVFEYMGM
CCCCCCCCCHHHHHHHCCCCEEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
KVLPSFIVYEASAMKQEKGIEELERYKKRISEL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVLYIFAHPEPKSFNAAMKDTAIAALKDKGHEVKLSDLYAMEFNPVLKASDFTERKNPD
CEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEHHHEEEEECCCCCCCCCCCCCCCCH
IFNAFLEAIKASKTGAFSSDIKEEMEKVKWADLLAFQFPIYFTSMPAIMKGWIDRVLAPG
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FGFNPITSSAYDTGLLKGKAAMLAFTTGAPKEMYSEGGAHGDIHRHLESITHCVFEYMGM
CCCCCCCCCHHHHHHHCCCCEEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
KVLPSFIVYEASAMKQEKGIEELERYKKRISEL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; NADPH; H+; acceptor

Specific reaction: NAD(P)H + H+ + acceptor = NAD(P)+ + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]