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The map label for this gene is cysU [H]

Identifier: 21227681

GI number: 21227681

Start: 1880730

End: 1881536

Strand: Reverse

Name: cysU [H]

Synonym: MM_1579

Alternate gene names: 21227681

Gene position: 1881536-1880730 (Counterclockwise)

Preceding gene: 21227682

Following gene: 21227680

Centisome position: 45.93

GC content: 47.46

Gene sequence:

>807_bases
ATGCGATGCTTAAAATCCCGGAGCGTGAACCACTCCTGGTTCAGGACCTTCACCGTGGGTATTGCCTGTACCTTCACTTT
TTTGCTCTTTATGACCATAGGGACCCTGCTCTTTGTGCTCAAACCTTCAGATCTTCTTTCATCCCTGCTTTCTGAAGAAA
TGCTTTATTCCATGAAGCTTTCCATGCTGACCTCTTCAGCCTCAACAATTTCCGTTATGTGCTGTTCAATTCCCACAGCC
TACGCACTTTCCCGTTTTTCCTTTCCCGGAAAAAGCGTAATAAAAACCGTACTCGGGCTTCCTATGGCATTTCCTGAACT
GGTAATGGGACTTGCGCTCCTGCTCCTTTTCGGGCAGGGATTCCTTGGACCTTACCTTGAAGCTCTGGGGATAAAGGTTA
CTTTCAGCAAGCTCGGGATAATAATTGCACAATTTTTTGTCGCTTTTCCCTATGCTGTAAGGGTCATCTACTCCACTTTT
GAAGATATCAACCCGAGATACGAACAGGTCTCGAGGAGCTTCGGGTACGGGGAATTCGAGACATTCCGACACGTTACCCT
TCCCATGGCAAGAAGCGGGCTATTTGCCTCGGGAGTAATTACCTTTGCCCGATGTATAGGAGCTTTCGGAGCCGTGCTGG
TGCTTGCAGGAGGATCATATATGCATACCGAAGTCCTGCCCGTTACTCTTTACCTGAACATTTCCTACGGAAACCTGGAA
ATGGCGATTACAAGCGGGATTTTGTTAATGGGAATAGCCTTTCTCGCAATCCTCAGCTTTGAGAAGTTTGAAGGAGGCAG
GATGTGA

Upstream 100 bases:

>100_bases
TTTCCATATATACCGAAGACCGTGAACTGGCAGAGGCATTTAACACTTATATTGCGGGCAAAGAAGCAAAAGAAACCTGG
AAAAAATGGGGCTTTGAGCC

Downstream 100 bases:

>100_bases
GCTTTCTTGAGGTAAGGGACCTCTGCCTTGATGTAGGAGATTTCGAACTCAGCGGGATAGGGCTCAAGGCTGAGAAAGGC
GATTACCTGGCTCTGATAGG

Product: molybdate ABC transporter permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MRCLKSRSVNHSWFRTFTVGIACTFTFLLFMTIGTLLFVLKPSDLLSSLLSEEMLYSMKLSMLTSSASTISVMCCSIPTA
YALSRFSFPGKSVIKTVLGLPMAFPELVMGLALLLLFGQGFLGPYLEALGIKVTFSKLGIIIAQFFVAFPYAVRVIYSTF
EDINPRYEQVSRSFGYGEFETFRHVTLPMARSGLFASGVITFARCIGAFGAVLVLAGGSYMHTEVLPVTLYLNISYGNLE
MAITSGILLMGIAFLAILSFEKFEGGRM

Sequences:

>Translated_268_residues
MRCLKSRSVNHSWFRTFTVGIACTFTFLLFMTIGTLLFVLKPSDLLSSLLSEEMLYSMKLSMLTSSASTISVMCCSIPTA
YALSRFSFPGKSVIKTVLGLPMAFPELVMGLALLLLFGQGFLGPYLEALGIKVTFSKLGIIIAQFFVAFPYAVRVIYSTF
EDINPRYEQVSRSFGYGEFETFRHVTLPMARSGLFASGVITFARCIGAFGAVLVLAGGSYMHTEVLPVTLYLNISYGNLE
MAITSGILLMGIAFLAILSFEKFEGGRM
>Mature_268_residues
MRCLKSRSVNHSWFRTFTVGIACTFTFLLFMTIGTLLFVLKPSDLLSSLLSEEMLYSMKLSMLTSSASTISVMCCSIPTA
YALSRFSFPGKSVIKTVLGLPMAFPELVMGLALLLLFGQGFLGPYLEALGIKVTFSKLGIIIAQFFVAFPYAVRVIYSTF
EDINPRYEQVSRSFGYGEFETFRHVTLPMARSGLFASGVITFARCIGAFGAVLVLAGGSYMHTEVLPVTLYLNISYGNLE
MAITSGILLMGIAFLAILSFEKFEGGRM

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0555

COG function: function code O; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=186, Percent_Identity=31.1827956989247, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082099, Length=237, Percent_Identity=28.6919831223629, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786980, Length=185, Percent_Identity=32.4324324324324, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786254, Length=201, Percent_Identity=26.865671641791, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787368, Length=159, Percent_Identity=28.3018867924528, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011865
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29438; Mature: 29438

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCLKSRSVNHSWFRTFTVGIACTFTFLLFMTIGTLLFVLKPSDLLSSLLSEEMLYSMKL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SMLTSSASTISVMCCSIPTAYALSRFSFPGKSVIKTVLGLPMAFPELVMGLALLLLFGQG
HHHHCCCHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
FLGPYLEALGIKVTFSKLGIIIAQFFVAFPYAVRVIYSTFEDINPRYEQVSRSFGYGEFE
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHH
TFRHVTLPMARSGLFASGVITFARCIGAFGAVLVLAGGSYMHTEVLPVTLYLNISYGNLE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHEEEEEEEEEEEEECCCH
MAITSGILLMGIAFLAILSFEKFEGGRM
HHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRCLKSRSVNHSWFRTFTVGIACTFTFLLFMTIGTLLFVLKPSDLLSSLLSEEMLYSMKL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SMLTSSASTISVMCCSIPTAYALSRFSFPGKSVIKTVLGLPMAFPELVMGLALLLLFGQG
HHHHCCCHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
FLGPYLEALGIKVTFSKLGIIIAQFFVAFPYAVRVIYSTFEDINPRYEQVSRSFGYGEFE
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHH
TFRHVTLPMARSGLFASGVITFARCIGAFGAVLVLAGGSYMHTEVLPVTLYLNISYGNLE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHEEEEEEEEEEEEECCCH
MAITSGILLMGIAFLAILSFEKFEGGRM
HHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2188958; 9205837; 9278503; 2188959 [H]