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The map label for this gene is rtcB [C]

Identifier: 21227640

GI number: 21227640

Start: 1836245

End: 1837747

Strand: Direct

Name: rtcB [C]

Synonym: MM_1538

Alternate gene names: 21227640

Gene position: 1836245-1837747 (Clockwise)

Preceding gene: 21227639

Following gene: 21227650

Centisome position: 44.83

GC content: 48.77

Gene sequence:

>1503_bases
ATGGTTGAGAGTGAAAATAAAGATATAGAAGAATCGGGTGCTGAAGTTGATAGGAGGGATGTCAGAAGCCTGGTCCGGAA
ACTTTCCGATAATAACTGGGAAATTCCAAAAGGGCACATTCCTAATATGAGAGTTCCAGGACGCCTTTTTGTATCTGAAA
AATTGCTTGAAGGCATTGAACCAGGTACAATTGACCAGATCGCAAACGTGGCAACACTTCCGGGAATCCAGAAATATTCC
ATGGCAATGCCTGATGCCCACCTGGGATATGGATTTGCTATAGGGGGCGTTGCAGCCTTTGACGTCGAAGAAGGAGTTAT
CAGCCCGGGAGGAGTGGGTTTTGATATTAACTGCGGTGTACGGCTTATCCGCACAAACCTTCAAAAGGAAGATGTCGTCC
CTCATATAAAGAGGCTGACAGATGAGCTGTTTAGTAATGTGCCTTCTGGTGTGGGTTCAAAAAGCCGTTTCAAGGCTTCT
GATAAAGAGCTGGACAGCGCATTTCTTGAAGGTGCAAAATGGGCAGTAGACGCTGGTTATGGGGTGGAAGCCGATGTTGA
ACATTGTGAGGGGAATGGTTTCCTTGAAGGAGCAGATACTTCTCATGTGAGTTCAAAGGCGAGAAACCGTGGAAAACCCC
AGTTAGGGACCCTCGGGAGCGGCAACCATTTCCTCGAAGTACAGTATGTAGATGAGATCTATGACCCGGAAGTGGCTTCA
GCCTTCGGGCTTGAAGAAGGCCAGGTCACGGTTATGGTTCACTGCGGGTCAAGGGGGGCAGGGCACCAGATATGTACCGA
CCACCTTAAAGAACTCTCCCAGGCTGTGAAGAGATATGGAATTGAGATTCCGGACAAACAGCTTGCCTGTGCTCCGGCTC
AGTCAAAAGAGGCACAGAATTATTTCAAAGCCATGCTCTGTGCTGCAAATTATGCATGGGCAAACAGGCAGATGATTACC
CACTGGACAAGAGAGTCTTTTGAAAAAATCTTTGGCAGGGATGCCGATGACATGGAAATGAGCCTCCTGTATGATGTTGC
CCATAATGTGGCAAAACTGGAAGAACACAGCATTGAAGGCAGGAAAAAAGAGGTTTACGTACACAGAAAAGGGGCAACAA
GAGCCTTTCCCGCAGGGCATCCGGAAGTTCCTTCCGCATACAGGGATGTGGGGCAGCCTGTTTTAATCCCCGGAAGCATG
GGGACTCCTTCATTCATACTCTGCGGTTCAACGGAATCTATGGACGTTTCTTTCGGTAGTGCCTGCCACGGAGCCGGGAG
AGTTATGAGCAGGGCGCATGCAAAGAAGGAATTCCACGGGCAGAGCATAAAAGAGGACCTTGAAGCTCATGGAATCACTG
TAAGGGCAACTCATCCCTCCGTGATTGCCGAAGAAGCTCCCGGTGTGTATAAGTCCAGCAGTGAAGTGGTAAATGTCGTG
CATGAACTTGGTATTGCCCGCAAGGTAGCAAGAGTTATCCCGCTCGGGGTTGCAAAAGGTTAA

Upstream 100 bases:

>100_bases
AGGACATCAGGGAAACATAAAGTAGAATAATTTTTGAATTATATTGATATCAGTATTTTAACTCAAAATTATATTTGCAA
TGGAGCAGGGAGTATAAATT

Downstream 100 bases:

>100_bases
ATGCGTGAAAATAGCCTTATTTTTTATTTTTCTTATTTTTTAACTGGATAATTTTTAGAAATCCTGTGGACAGTATTATT
CCCCCGAAATAAAATCTGGC

Product: replication factor C subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MVESENKDIEESGAEVDRRDVRSLVRKLSDNNWEIPKGHIPNMRVPGRLFVSEKLLEGIEPGTIDQIANVATLPGIQKYS
MAMPDAHLGYGFAIGGVAAFDVEEGVISPGGVGFDINCGVRLIRTNLQKEDVVPHIKRLTDELFSNVPSGVGSKSRFKAS
DKELDSAFLEGAKWAVDAGYGVEADVEHCEGNGFLEGADTSHVSSKARNRGKPQLGTLGSGNHFLEVQYVDEIYDPEVAS
AFGLEEGQVTVMVHCGSRGAGHQICTDHLKELSQAVKRYGIEIPDKQLACAPAQSKEAQNYFKAMLCAANYAWANRQMIT
HWTRESFEKIFGRDADDMEMSLLYDVAHNVAKLEEHSIEGRKKEVYVHRKGATRAFPAGHPEVPSAYRDVGQPVLIPGSM
GTPSFILCGSTESMDVSFGSACHGAGRVMSRAHAKKEFHGQSIKEDLEAHGITVRATHPSVIAEEAPGVYKSSSEVVNVV
HELGIARKVARVIPLGVAKG

Sequences:

>Translated_500_residues
MVESENKDIEESGAEVDRRDVRSLVRKLSDNNWEIPKGHIPNMRVPGRLFVSEKLLEGIEPGTIDQIANVATLPGIQKYS
MAMPDAHLGYGFAIGGVAAFDVEEGVISPGGVGFDINCGVRLIRTNLQKEDVVPHIKRLTDELFSNVPSGVGSKSRFKAS
DKELDSAFLEGAKWAVDAGYGVEADVEHCEGNGFLEGADTSHVSSKARNRGKPQLGTLGSGNHFLEVQYVDEIYDPEVAS
AFGLEEGQVTVMVHCGSRGAGHQICTDHLKELSQAVKRYGIEIPDKQLACAPAQSKEAQNYFKAMLCAANYAWANRQMIT
HWTRESFEKIFGRDADDMEMSLLYDVAHNVAKLEEHSIEGRKKEVYVHRKGATRAFPAGHPEVPSAYRDVGQPVLIPGSM
GTPSFILCGSTESMDVSFGSACHGAGRVMSRAHAKKEFHGQSIKEDLEAHGITVRATHPSVIAEEAPGVYKSSSEVVNVV
HELGIARKVARVIPLGVAKG
>Mature_500_residues
MVESENKDIEESGAEVDRRDVRSLVRKLSDNNWEIPKGHIPNMRVPGRLFVSEKLLEGIEPGTIDQIANVATLPGIQKYS
MAMPDAHLGYGFAIGGVAAFDVEEGVISPGGVGFDINCGVRLIRTNLQKEDVVPHIKRLTDELFSNVPSGVGSKSRFKAS
DKELDSAFLEGAKWAVDAGYGVEADVEHCEGNGFLEGADTSHVSSKARNRGKPQLGTLGSGNHFLEVQYVDEIYDPEVAS
AFGLEEGQVTVMVHCGSRGAGHQICTDHLKELSQAVKRYGIEIPDKQLACAPAQSKEAQNYFKAMLCAANYAWANRQMIT
HWTRESFEKIFGRDADDMEMSLLYDVAHNVAKLEEHSIEGRKKEVYVHRKGATRAFPAGHPEVPSAYRDVGQPVLIPGSM
GTPSFILCGSTESMDVSFGSACHGAGRVMSRAHAKKEFHGQSIKEDLEAHGITVRATHPSVIAEEAPGVYKSSSEVVNVV
HELGIARKVARVIPLGVAKG

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=500, Percent_Identity=45.6, Blast_Score=468, Evalue=1e-132,
Organism=Escherichia coli, GI2367224, Length=437, Percent_Identity=31.1212814645309, Blast_Score=145, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17506665, Length=496, Percent_Identity=49.7983870967742, Blast_Score=495, Evalue=1e-140,
Organism=Drosophila melanogaster, GI24585217, Length=495, Percent_Identity=48.0808080808081, Blast_Score=464, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 54273; Mature: 54273

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS01288 UPF0027

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVESENKDIEESGAEVDRRDVRSLVRKLSDNNWEIPKGHIPNMRVPGRLFVSEKLLEGIE
CCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
PGTIDQIANVATLPGIQKYSMAMPDAHLGYGFAIGGVAAFDVEEGVISPGGVGFDINCGV
CCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCEEECCEEEEECCCCCCCCCCCCEECCCCC
RLIRTNLQKEDVVPHIKRLTDELFSNVPSGVGSKSRFKASDKELDSAFLEGAKWAVDAGY
EEEHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHCCCCEEEECCC
GVEADVEHCEGNGFLEGADTSHVSSKARNRGKPQLGTLGSGNHFLEVQYVDEIYDPEVAS
CCCCCHHHCCCCCEECCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEEEHHHHCCCHHHH
AFGLEEGQVTVMVHCGSRGAGHQICTDHLKELSQAVKRYGIEIPDKQLACAPAQSKEAQN
HCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHH
YFKAMLCAANYAWANRQMITHWTRESFEKIFGRDADDMEMSLLYDVAHNVAKLEEHSIEG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
RKKEVYVHRKGATRAFPAGHPEVPSAYRDVGQPVLIPGSMGTPSFILCGSTESMDVSFGS
CCEEEEEEECCCCCCCCCCCCCCCHHHHHCCCCEEEECCCCCCCEEEECCCCCCCCCCCC
ACHGAGRVMSRAHAKKEFHGQSIKEDLEAHGITVRATHPSVIAEEAPGVYKSSSEVVNVV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEECCCCHHHHCCCCCCCCHHHHHHHH
HELGIARKVARVIPLGVAKG
HHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVESENKDIEESGAEVDRRDVRSLVRKLSDNNWEIPKGHIPNMRVPGRLFVSEKLLEGIE
CCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
PGTIDQIANVATLPGIQKYSMAMPDAHLGYGFAIGGVAAFDVEEGVISPGGVGFDINCGV
CCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCEEECCEEEEECCCCCCCCCCCCEECCCCC
RLIRTNLQKEDVVPHIKRLTDELFSNVPSGVGSKSRFKASDKELDSAFLEGAKWAVDAGY
EEEHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHCCCCEEEECCC
GVEADVEHCEGNGFLEGADTSHVSSKARNRGKPQLGTLGSGNHFLEVQYVDEIYDPEVAS
CCCCCHHHCCCCCEECCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEEEHHHHCCCHHHH
AFGLEEGQVTVMVHCGSRGAGHQICTDHLKELSQAVKRYGIEIPDKQLACAPAQSKEAQN
HCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHH
YFKAMLCAANYAWANRQMITHWTRESFEKIFGRDADDMEMSLLYDVAHNVAKLEEHSIEG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
RKKEVYVHRKGATRAFPAGHPEVPSAYRDVGQPVLIPGSMGTPSFILCGSTESMDVSFGS
CCEEEEEEECCCCCCCCCCCCCCCHHHHHCCCCEEEECCCCCCCEEEECCCCCCCCCCCC
ACHGAGRVMSRAHAKKEFHGQSIKEDLEAHGITVRATHPSVIAEEAPGVYKSSSEVVNVV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEECCCCHHHHCCCCCCCCHHHHHHHH
HELGIARKVARVIPLGVAKG
HHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]