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The map label for this gene is cdc6 [H]

Identifier: 21227480

GI number: 21227480

Start: 1655076

End: 1656197

Strand: Direct

Name: cdc6 [H]

Synonym: MM_1378

Alternate gene names: 21227480

Gene position: 1655076-1656197 (Clockwise)

Preceding gene: 21227478

Following gene: 21227482

Centisome position: 40.4

GC content: 43.85

Gene sequence:

>1122_bases
TTGACAGGTAACGATATACTACTCTGGGACGAAACCCTATTTAAGGACCTTTCGGTACTTGAGCCGGATTATCTCCCGGA
ATACTTTCCCCACAGGGATTCGCAGTTAAACGCGCTCAGGTTTGCACTTAAACCGGCTCTGCGCGGTATGCGTCCTTTAA
ATTGTTTGCTGGTCGGGCCTCCAGGTACAGGAAAAACAAGTGCAATCATGAAAACATTCAGAGAAGTTGAAGCTCATGCT
CCAAATGTTGTTACTGTAAAGGTCAACTGCCAGATTGATTCTACACGTTTTGCCGTGATGTCAAGGATTTACAGGCAACT
TTTCGGGATCTCTCCACCTAATTCCGGGATTGCTTTTAGGAAGCTCTTTGAAACCGTTGTAAATTTCCTGGTTTCCTCGG
AGAAAGTCCTGATTGTAGCGCTGGACGACCTTAATTATCTCTGCTGCGAAGGCCATGCCAATGAAGTAATGTATTCTTTG
CTAAGGGCTCATGAGCAGTATCCAGGGGCAAAGATCGGGGTTATAGGGATCGTAAATGACGCATCTGACCTTTACTGCCT
GGATTCAAGAGTTAACTCTGTTTTTCTGCCTGAAGAAGTATCTTTCCCAAGATATGAGGAAGGAGAGATTCTGGATATCC
TGAAGGACAGAGTCAGGTACGGTTTTTATCCGAAAGTAATCTCTGATGAAGTTCTGAAACTTGTTGTCTCTTATGTGGAA
AAGACAGGAGACTTGAGGGTTGGAATTGACCTTCTCAGACGTTCGGGCTTTAATGCCGAACGCAAAGGAAGACGCATGAT
TTTATTTGAGGACGTTGAAAAAGCATATGAGGCATCCAAACTGCTCCACCTTTGCAGGGGAATAAGCCTCCTTTCGGATC
CTGAAAAACAGCTGCTTGAACTGATAGCAAAGAAAGATGAAATTAAAGCTGGAGAGCTCTATAAATCCTTCCATGAGCTT
ACACAGTTAGGATACACCCGCTTTTACGGAATGGTCAACAGGCTTCAGACCCTTAACTATGTTGATGCCGATTTTACAGG
CAAAGGCAAGAGAGGCAGGACACGGATAATAAAAACAAAATATGAAGCTGAAGACATCCTTAATTGCCTTAAAAAAGCCT
GA

Upstream 100 bases:

>100_bases
AAAATCAGTATCCTGTAATCACAGGAAATCCACTGATAAAAATTGGGCGATAAAAATGCCGCATTAAAATACACATCCAT
TTAAAAAGGAGCAGGTTTCC

Downstream 100 bases:

>100_bases
AAGAGAAAAAAGAACGTAGATTCACATGGATTTTCCGTTGAGAGTTCGGAAAACTTCTTTCAGACCTGGAGCATTTTCTG
ACTGAATTTTAAAAAAGGAG

Product: cell division control protein 6

Products: NA

Alternate protein names: CDC6 homolog 2 [H]

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MTGNDILLWDETLFKDLSVLEPDYLPEYFPHRDSQLNALRFALKPALRGMRPLNCLLVGPPGTGKTSAIMKTFREVEAHA
PNVVTVKVNCQIDSTRFAVMSRIYRQLFGISPPNSGIAFRKLFETVVNFLVSSEKVLIVALDDLNYLCCEGHANEVMYSL
LRAHEQYPGAKIGVIGIVNDASDLYCLDSRVNSVFLPEEVSFPRYEEGEILDILKDRVRYGFYPKVISDEVLKLVVSYVE
KTGDLRVGIDLLRRSGFNAERKGRRMILFEDVEKAYEASKLLHLCRGISLLSDPEKQLLELIAKKDEIKAGELYKSFHEL
TQLGYTRFYGMVNRLQTLNYVDADFTGKGKRGRTRIIKTKYEAEDILNCLKKA

Sequences:

>Translated_373_residues
MTGNDILLWDETLFKDLSVLEPDYLPEYFPHRDSQLNALRFALKPALRGMRPLNCLLVGPPGTGKTSAIMKTFREVEAHA
PNVVTVKVNCQIDSTRFAVMSRIYRQLFGISPPNSGIAFRKLFETVVNFLVSSEKVLIVALDDLNYLCCEGHANEVMYSL
LRAHEQYPGAKIGVIGIVNDASDLYCLDSRVNSVFLPEEVSFPRYEEGEILDILKDRVRYGFYPKVISDEVLKLVVSYVE
KTGDLRVGIDLLRRSGFNAERKGRRMILFEDVEKAYEASKLLHLCRGISLLSDPEKQLLELIAKKDEIKAGELYKSFHEL
TQLGYTRFYGMVNRLQTLNYVDADFTGKGKRGRTRIIKTKYEAEDILNCLKKA
>Mature_372_residues
TGNDILLWDETLFKDLSVLEPDYLPEYFPHRDSQLNALRFALKPALRGMRPLNCLLVGPPGTGKTSAIMKTFREVEAHAP
NVVTVKVNCQIDSTRFAVMSRIYRQLFGISPPNSGIAFRKLFETVVNFLVSSEKVLIVALDDLNYLCCEGHANEVMYSLL
RAHEQYPGAKIGVIGIVNDASDLYCLDSRVNSVFLPEEVSFPRYEEGEILDILKDRVRYGFYPKVISDEVLKLVVSYVEK
TGDLRVGIDLLRRSGFNAERKGRRMILFEDVEKAYEASKLLHLCRGISLLSDPEKQLLELIAKKDEIKAGELYKSFHELT
QLGYTRFYGMVNRLQTLNYVDADFTGKGKRGRTRIIKTKYEAEDILNCLKKA

Specific function: Might be involved in the initiation of DNA replication [H]

COG id: COG1474

COG function: function code LO; Cdc6-related protein, AAA superfamily ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDC6/cdc18 family [H]

Homologues:

Organism=Homo sapiens, GI4502703, Length=252, Percent_Identity=23.015873015873, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21355681, Length=242, Percent_Identity=26.8595041322314, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR015163
- InterPro:   IPR014277
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00004 AAA; PF09079 Cdc6_C [H]

EC number: NA

Molecular weight: Translated: 42440; Mature: 42309

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGNDILLWDETLFKDLSVLEPDYLPEYFPHRDSQLNALRFALKPALRGMRPLNCLLVGP
CCCCCEEEECHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECC
PGTGKTSAIMKTFREVEAHAPNVVTVKVNCQIDSTRFAVMSRIYRQLFGISPPNSGIAFR
CCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHH
KLFETVVNFLVSSEKVLIVALDDLNYLCCEGHANEVMYSLLRAHEQYPGAKIGVIGIVND
HHHHHHHHHHHCCCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEECC
ASDLYCLDSRVNSVFLPEEVSFPRYEEGEILDILKDRVRYGFYPKVISDEVLKLVVSYVE
CCCEEEECCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KTGDLRVGIDLLRRSGFNAERKGRRMILFEDVEKAYEASKLLHLCRGISLLSDPEKQLLE
HCCCHHHHHHHHHHCCCCHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHH
LIAKKDEIKAGELYKSFHELTQLGYTRFYGMVNRLQTLNYVDADFTGKGKRGRTRIIKTK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECH
YEAEDILNCLKKA
HHHHHHHHHHHCC
>Mature Secondary Structure 
TGNDILLWDETLFKDLSVLEPDYLPEYFPHRDSQLNALRFALKPALRGMRPLNCLLVGP
CCCCEEEECHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECC
PGTGKTSAIMKTFREVEAHAPNVVTVKVNCQIDSTRFAVMSRIYRQLFGISPPNSGIAFR
CCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHH
KLFETVVNFLVSSEKVLIVALDDLNYLCCEGHANEVMYSLLRAHEQYPGAKIGVIGIVND
HHHHHHHHHHHCCCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEECC
ASDLYCLDSRVNSVFLPEEVSFPRYEEGEILDILKDRVRYGFYPKVISDEVLKLVVSYVE
CCCEEEECCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KTGDLRVGIDLLRRSGFNAERKGRRMILFEDVEKAYEASKLLHLCRGISLLSDPEKQLLE
HCCCHHHHHHHHHHCCCCHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHH
LIAKKDEIKAGELYKSFHELTQLGYTRFYGMVNRLQTLNYVDADFTGKGKRGRTRIIKTK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECH
YEAEDILNCLKKA
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]