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The map label for this gene is thiL [H]

Identifier: 21227467

GI number: 21227467

Start: 1633412

End: 1634425

Strand: Reverse

Name: thiL [H]

Synonym: MM_1365

Alternate gene names: 21227467

Gene position: 1634425-1633412 (Counterclockwise)

Preceding gene: 21227468

Following gene: 21227466

Centisome position: 39.9

GC content: 48.32

Gene sequence:

>1014_bases
ATGAAAGAAACAAAAGTGTCTTCAATCGGAGAGCGTGCTTTAATCTCGCGCTTATCTGAGATTTTCAATGCCCCTGATGG
AGAGGAAAGAAGACAGGAAGAAGTCCTGATAGGTGCCGGTTCTGATGACTGTGCTGTCCTTGACCTGAAAGGTGAAGACT
ACCTGGTTGTTACGACTGATATGCTTCACATGACCACAGATTTTCCTGAAGGGATGACCCCCTGGCAGATGGGCTGGATG
TCTGCAGCCGTAAACCTGAGCGATATAGCTGCCATGGGTGCAGAGCCCACAGGGCTGCTAATGGCAATAGGCATGCCTTC
GGATACCGAAATCGCTTTTGTCGAAGAGCTTGCAAAAGGAATACAGGCATGTGCCGCGTTCTGCGGGACTTCTGTTATAG
GAGGCGACCTTGATACCCATGCCGAGCTGACAATTACAGGGACAGCCCTGGGAAGAGTGAAAAAAAGCCAGCTCCTTCTT
CGAAAAGGGGCAAAACCCGGAGACCTTGTCTGTGTAACGGGATATGCAGGGTCAGCCGGAGCTGCCCTTAAAGCGGTCCA
GTCAAAAAAACCGGTGAGTGAAAACGTCCTGAAAGCTCTTTTTGAACCGGTCCCACGAACAAGGGAAGCTAAACAGCTTG
CTGAGTCGGGTGCGGTCACGTCCATGATGGACACGAGTGACGGACTTGCTATGTCTCTTTACGACCTTTCCAGGCAGAGT
AAAACAGGATTTAAAATCCGGGAAAATGCCCTTCCAATTCTCCCGGAAGTCAGGAAGTTTGCCTCAGGTCCAGAAGAACT
TCTGGAATTTGCACTTTATACAGGCGGAGACTTCGAACTTATTTTTACAATTGATCCGGAACGCCTAAAAAAAGTACAAA
ATATATGTAACTTGACTATCATAGGAGAATGCACAGAGTATGAAACTGGTATCATGCTTGAATCCCCGGAATGCAGGCTG
ACAGCTATAAAACAGCTGGGATACCAGCAGCTAAAAGCCGAAACGGCTGATTAG

Upstream 100 bases:

>100_bases
AAAAATTAAATAAAGGAGATTGACTCAGTCAATCTTAGCCCAAAAAAGGGAAAACATCTACAAAAAAGAAATAGGAAGTA
ATCGCTTCTAAAAAATGACC

Downstream 100 bases:

>100_bases
CTTTCCTGAATAACTGACGTTAATCCCCCATATATTAAAAGCCTGAAATGAAAGAAAAAATTAAGAAATAAAGACTGGAA
GGCTTATACTACCATAAAAA

Product: thiamin-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKETKVSSIGERALISRLSEIFNAPDGEERRQEEVLIGAGSDDCAVLDLKGEDYLVVTTDMLHMTTDFPEGMTPWQMGWM
SAAVNLSDIAAMGAEPTGLLMAIGMPSDTEIAFVEELAKGIQACAAFCGTSVIGGDLDTHAELTITGTALGRVKKSQLLL
RKGAKPGDLVCVTGYAGSAGAALKAVQSKKPVSENVLKALFEPVPRTREAKQLAESGAVTSMMDTSDGLAMSLYDLSRQS
KTGFKIRENALPILPEVRKFASGPEELLEFALYTGGDFELIFTIDPERLKKVQNICNLTIIGECTEYETGIMLESPECRL
TAIKQLGYQQLKAETAD

Sequences:

>Translated_337_residues
MKETKVSSIGERALISRLSEIFNAPDGEERRQEEVLIGAGSDDCAVLDLKGEDYLVVTTDMLHMTTDFPEGMTPWQMGWM
SAAVNLSDIAAMGAEPTGLLMAIGMPSDTEIAFVEELAKGIQACAAFCGTSVIGGDLDTHAELTITGTALGRVKKSQLLL
RKGAKPGDLVCVTGYAGSAGAALKAVQSKKPVSENVLKALFEPVPRTREAKQLAESGAVTSMMDTSDGLAMSLYDLSRQS
KTGFKIRENALPILPEVRKFASGPEELLEFALYTGGDFELIFTIDPERLKKVQNICNLTIIGECTEYETGIMLESPECRL
TAIKQLGYQQLKAETAD
>Mature_337_residues
MKETKVSSIGERALISRLSEIFNAPDGEERRQEEVLIGAGSDDCAVLDLKGEDYLVVTTDMLHMTTDFPEGMTPWQMGWM
SAAVNLSDIAAMGAEPTGLLMAIGMPSDTEIAFVEELAKGIQACAAFCGTSVIGGDLDTHAELTITGTALGRVKKSQLLL
RKGAKPGDLVCVTGYAGSAGAALKAVQSKKPVSENVLKALFEPVPRTREAKQLAESGAVTSMMDTSDGLAMSLYDLSRQS
KTGFKIRENALPILPEVRKFASGPEELLEFALYTGGDFELIFTIDPERLKKVQNICNLTIIGECTEYETGIMLESPECRL
TAIKQLGYQQLKAETAD

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=283, Percent_Identity=32.8621908127208, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 36271; Mature: 36271

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKETKVSSIGERALISRLSEIFNAPDGEERRQEEVLIGAGSDDCAVLDLKGEDYLVVTTD
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCEEEEECCCCCEEEEEECCCCEEEEEEH
MLHMTTDFPEGMTPWQMGWMSAAVNLSDIAAMGAEPTGLLMAIGMPSDTEIAFVEELAKG
HEEEECCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHH
IQACAAFCGTSVIGGDLDTHAELTITGTALGRVKKSQLLLRKGAKPGDLVCVTGYAGSAG
HHHHHHHHCCHHCCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCH
AALKAVQSKKPVSENVLKALFEPVPRTREAKQLAESGAVTSMMDTSDGLAMSLYDLSRQS
HHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCCCEEEHHHHCCCC
KTGFKIRENALPILPEVRKFASGPEELLEFALYTGGDFELIFTIDPERLKKVQNICNLTI
CCCCEEECCCCCCCHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHCEEE
IGECTEYETGIMLESPECRLTAIKQLGYQQLKAETAD
EECCCCCCCCEEEECCCHHHHHHHHHCHHHHHHCCCC
>Mature Secondary Structure
MKETKVSSIGERALISRLSEIFNAPDGEERRQEEVLIGAGSDDCAVLDLKGEDYLVVTTD
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCEEEEECCCCCEEEEEECCCCEEEEEEH
MLHMTTDFPEGMTPWQMGWMSAAVNLSDIAAMGAEPTGLLMAIGMPSDTEIAFVEELAKG
HEEEECCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHH
IQACAAFCGTSVIGGDLDTHAELTITGTALGRVKKSQLLLRKGAKPGDLVCVTGYAGSAG
HHHHHHHHCCHHCCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCH
AALKAVQSKKPVSENVLKALFEPVPRTREAKQLAESGAVTSMMDTSDGLAMSLYDLSRQS
HHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCCCEEEHHHHCCCC
KTGFKIRENALPILPEVRKFASGPEELLEFALYTGGDFELIFTIDPERLKKVQNICNLTI
CCCCEEECCCCCCCHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHCEEE
IGECTEYETGIMLESPECRLTAIKQLGYQQLKAETAD
EECCCCCCCCEEEECCCHHHHHHHHHCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]