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The map label for this gene is 21227364

Identifier: 21227364

GI number: 21227364

Start: 1497661

End: 1498428

Strand: Reverse

Name: 21227364

Synonym: MM_1262

Alternate gene names: NA

Gene position: 1498428-1497661 (Counterclockwise)

Preceding gene: 21227368

Following gene: 21227363

Centisome position: 36.58

GC content: 41.54

Gene sequence:

>768_bases
GTGCCTGGGCATGCGTGCCCCCCAAACAGCATAATTTCCTGTCAATACCGGGTTTCGGATCCGGGAGGGTTTTATATAGA
ATCGTTTAGATGCGTGCTTACAAATTGGGATTATATTTACAATCTGTGCCGAAACATTTCAAGAGAAGTCAAAAGTTCCG
GTTACGAGCCGGATGTTATTATTGCACTGGCCAGAGGAGGCTGGTTTGCAGGACGCGTGCTATGTGATTTTCTGGGACTT
GATGACCTGTCCAGTCTTAAGGTCGAGCACTATATAGGGGCTGTAGCTATTGACACCGGTGAACCGTATATACGGTATCC
TCTTTCTGATAATGTAATTAAAGGTAAAAAAGTGCTTATTGTAGATGATATTGTGGATACCGGGGAAAGTATGATCAGCG
CTAAAACTTATGTGGAAAGCAGAAATCCCAGCGAGGTACGGACTGCTTCCTTGCAGTACCTGGGAAGCTCAAAAATAGAT
CCTGATTATGTAGGAGAACGTCTTGAAGATTGGGCATGGATTGTTTATCCCTGGAATTTTATGGAAGACATGATAAGCAT
TCTGACAAAAAACATGAGAAAAGAACCAGAAAAGCACTGGAGTTTAGAAGATATTAAACATAGCCTTTACATAAATCATG
CCCTTGACCCTGTGGTTTTTGAAATTACTCAACCTGGCAGGCTTCAGGAAGTTCTGGAAGAAATGGATCGAATCCATAGA
ACTACTTCCAATGTTATTAATAGGAAAAAGTACTGGAGACTTTTATAA

Upstream 100 bases:

>100_bases
TCCACTTTAAAATATTTCTTTTCAATTCTTTCCCAAACTATTTTTTGACAAGATAAGAAAACTTAAAGCCTATGGGCTAA
ATTATATAATCTCGAAGGTG

Downstream 100 bases:

>100_bases
AATAGATTTTTATGTCATGTTCTCGATAATTGTTTTTGATGTAAATTTTGATGTAAATAATCTGCATCGGGTAAGGTAAA
TAATGAGTAAATAAGAGTAA

Product: xanthine-guanine phosphoribosyltransferase

Products: 5-phospho-alpha-D-ribose 1-diphosphate; xanthine

Alternate protein names: Purine Phosphoribosyltransferase; Xanthine-Guanine Phosphoribosyltransferase; Hypoxanthine/Guanine Phosphoribosyltransferase; Phosphoribosyl Transferase Domain Protein; Phosphoribosyl Transferase Domain-Containing Protein; Phosphoribosyl Transferase; Hypoxanthine-Guanine Phosphoribosyltransferase; Xanthine-Guanine Phosphoribosyltransferase Conjectural; Phosphoribosyltransferase-Like Protein; Nucleotide Phosphoribosyltransferase; Purine Phosphoribosyltransferase Related Protein

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MPGHACPPNSIISCQYRVSDPGGFYIESFRCVLTNWDYIYNLCRNISREVKSSGYEPDVIIALARGGWFAGRVLCDFLGL
DDLSSLKVEHYIGAVAIDTGEPYIRYPLSDNVIKGKKVLIVDDIVDTGESMISAKTYVESRNPSEVRTASLQYLGSSKID
PDYVGERLEDWAWIVYPWNFMEDMISILTKNMRKEPEKHWSLEDIKHSLYINHALDPVVFEITQPGRLQEVLEEMDRIHR
TTSNVINRKKYWRLL

Sequences:

>Translated_255_residues
MPGHACPPNSIISCQYRVSDPGGFYIESFRCVLTNWDYIYNLCRNISREVKSSGYEPDVIIALARGGWFAGRVLCDFLGL
DDLSSLKVEHYIGAVAIDTGEPYIRYPLSDNVIKGKKVLIVDDIVDTGESMISAKTYVESRNPSEVRTASLQYLGSSKID
PDYVGERLEDWAWIVYPWNFMEDMISILTKNMRKEPEKHWSLEDIKHSLYINHALDPVVFEITQPGRLQEVLEEMDRIHR
TTSNVINRKKYWRLL
>Mature_254_residues
PGHACPPNSIISCQYRVSDPGGFYIESFRCVLTNWDYIYNLCRNISREVKSSGYEPDVIIALARGGWFAGRVLCDFLGLD
DLSSLKVEHYIGAVAIDTGEPYIRYPLSDNVIKGKKVLIVDDIVDTGESMISAKTYVESRNPSEVRTASLQYLGSSKIDP
DYVGERLEDWAWIVYPWNFMEDMISILTKNMRKEPEKHWSLEDIKHSLYINHALDPVVFEITQPGRLQEVLEEMDRIHRT
TSNVINRKKYWRLL

Specific function: Unknown

COG id: COG2236

COG function: function code R; Predicted phosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.4.2.22

Molecular weight: Translated: 29374; Mature: 29243

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGHACPPNSIISCQYRVSDPGGFYIESFRCVLTNWDYIYNLCRNISREVKSSGYEPDVI
CCCCCCCCCCEEEEEEEECCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEE
IALARGGWFAGRVLCDFLGLDDLSSLKVEHYIGAVAIDTGEPYIRYPLSDNVIKGKKVLI
EEEECCCCHHHHHHHHHHCCCCHHHHHHHHHEEEEEEECCCCEEEECCCCCEECCCEEEE
VDDIVDTGESMISAKTYVESRNPSEVRTASLQYLGSSKIDPDYVGERLEDWAWIVYPWNF
EECHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEECHHH
MEDMISILTKNMRKEPEKHWSLEDIKHSLYINHALDPVVFEITQPGRLQEVLEEMDRIHR
HHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHH
TTSNVINRKKYWRLL
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
PGHACPPNSIISCQYRVSDPGGFYIESFRCVLTNWDYIYNLCRNISREVKSSGYEPDVI
CCCCCCCCCEEEEEEEECCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEE
IALARGGWFAGRVLCDFLGLDDLSSLKVEHYIGAVAIDTGEPYIRYPLSDNVIKGKKVLI
EEEECCCCHHHHHHHHHHCCCCHHHHHHHHHEEEEEEECCCCEEEECCCCCEECCCEEEE
VDDIVDTGESMISAKTYVESRNPSEVRTASLQYLGSSKIDPDYVGERLEDWAWIVYPWNF
EECHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEECHHH
MEDMISILTKNMRKEPEKHWSLEDIKHSLYINHALDPVVFEITQPGRLQEVLEEMDRIHR
HHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHH
TTSNVINRKKYWRLL
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 9-(5-phospho-beta-D-ribosyl)xanthine; diphosphate

Specific reaction: 9-(5-phospho-beta-D-ribosyl)xanthine + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA