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The map label for this gene is serB [C]

Identifier: 21227209

GI number: 21227209

Start: 1300831

End: 1301538

Strand: Reverse

Name: serB [C]

Synonym: MM_1107

Alternate gene names: 21227209

Gene position: 1301538-1300831 (Counterclockwise)

Preceding gene: 21227211

Following gene: 21227208

Centisome position: 31.77

GC content: 46.75

Gene sequence:

>708_bases
GTGAACTGTCCTATAAACGATTCTACTGAAAACAAACTCATTGTTTTTGATATGGATAGCACCCTTATAGACGCTGAGAC
TATCGATGAGCTCGCCAGGGCTGCAGGTGTTGTAAGCAAAGTAGAGGAGATTACGAATAGAGCGATGCATGGAGACCTCG
ATTTCGAGCAAGCGCTTGCAGAAAGGGTCAGACTTCTTGAGGGTCTTCCTGTGGAAACTGCCCTTGATGCTGTAAACCAG
ATAAATCTAATGCCGGGAGCAGCAGAACTTGTCCTGTATGTCAAAAGTCGGGGTTATAAGACTGCTATGATTTCCGGTGG
GTTTACCATAGCCGCCGAGAGGATAGGTAAAACGCTTGGTATCGATTTTGTTGTTTCTAACGAACTGCTTGTGGAAGATG
GCTATCTCCTGGGAGAAGTTGTCGGCCCTGTCACACAAAGTGATTCCAAAGCAAAGGTGTTCGAGGAACTGGCACAGCTC
TACAATGTCAGGCCCGAGCAGTGTGTGGTTGTCGGGGACGGCGCAAACGATGCCTGTATTTTTGAGATAGCAGGTTTTGC
CATAGCTTTCAATCCAAAGCCCATCCTTAGGGAGTATGCGGACGTGGTCATAACAGTAAAAGACCTGAGGGCCGTAATCC
CTGTTCTTGAATCTCTTTCTTATCAATGTTGTAATCAGGCACAGCATGTCGACATCGAACACTACTAA

Upstream 100 bases:

>100_bases
AACTGTGGGGGTACCTCTGAAACGGTACTTCGGGCAGTATGCCCTATTTCGGGAATTGTCCCGCTATATCTATAGATATT
CAGGTCCAGGTTTTGATTGA

Downstream 100 bases:

>100_bases
AATGCCAGCTTTTTTGCTGGACCGGGAGGCACAATAAGAGATGCTAAAGGAATTGCAGAAAAAAAGATCAGATTTGAAGG
ACATTTCTGAAGAATCCAAA

Product: putative phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MNCPINDSTENKLIVFDMDSTLIDAETIDELARAAGVVSKVEEITNRAMHGDLDFEQALAERVRLLEGLPVETALDAVNQ
INLMPGAAELVLYVKSRGYKTAMISGGFTIAAERIGKTLGIDFVVSNELLVEDGYLLGEVVGPVTQSDSKAKVFEELAQL
YNVRPEQCVVVGDGANDACIFEIAGFAIAFNPKPILREYADVVITVKDLRAVIPVLESLSYQCCNQAQHVDIEHY

Sequences:

>Translated_235_residues
MNCPINDSTENKLIVFDMDSTLIDAETIDELARAAGVVSKVEEITNRAMHGDLDFEQALAERVRLLEGLPVETALDAVNQ
INLMPGAAELVLYVKSRGYKTAMISGGFTIAAERIGKTLGIDFVVSNELLVEDGYLLGEVVGPVTQSDSKAKVFEELAQL
YNVRPEQCVVVGDGANDACIFEIAGFAIAFNPKPILREYADVVITVKDLRAVIPVLESLSYQCCNQAQHVDIEHY
>Mature_235_residues
MNCPINDSTENKLIVFDMDSTLIDAETIDELARAAGVVSKVEEITNRAMHGDLDFEQALAERVRLLEGLPVETALDAVNQ
INLMPGAAELVLYVKSRGYKTAMISGGFTIAAERIGKTLGIDFVVSNELLVEDGYLLGEVVGPVTQSDSKAKVFEELAQL
YNVRPEQCVVVGDGANDACIFEIAGFAIAFNPKPILREYADVVITVKDLRAVIPVLESLSYQCCNQAQHVDIEHY

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=176, Percent_Identity=36.3636363636364, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1790849, Length=206, Percent_Identity=42.2330097087379, Blast_Score=154, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI115534456, Length=176, Percent_Identity=34.0909090909091, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI115534454, Length=176, Percent_Identity=34.0909090909091, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI115534458, Length=178, Percent_Identity=33.7078651685393, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=207, Percent_Identity=41.5458937198068, Blast_Score=151, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24661601, Length=191, Percent_Identity=29.8429319371728, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 25638; Mature: 25638

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCPINDSTENKLIVFDMDSTLIDAETIDELARAAGVVSKVEEITNRAMHGDLDFEQALA
CCCCCCCCCCCEEEEEECCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ERVRLLEGLPVETALDAVNQINLMPGAAELVLYVKSRGYKTAMISGGFTIAAERIGKTLG
HHHHHHHCCCHHHHHHHHHHCCCCCCHHHEEEEEECCCCEEEEEECCCEEEHHHCCHHHC
IDFVVSNELLVEDGYLLGEVVGPVTQSDSKAKVFEELAQLYNVRPEQCVVVGDGANDACI
EEEEEECCEEEECCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEE
FEIAGFAIAFNPKPILREYADVVITVKDLRAVIPVLESLSYQCCNQAQHVDIEHY
EEEECEEEEECCCHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNCPINDSTENKLIVFDMDSTLIDAETIDELARAAGVVSKVEEITNRAMHGDLDFEQALA
CCCCCCCCCCCEEEEEECCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ERVRLLEGLPVETALDAVNQINLMPGAAELVLYVKSRGYKTAMISGGFTIAAERIGKTLG
HHHHHHHCCCHHHHHHHHHHCCCCCCHHHEEEEEECCCCEEEEEECCCEEEHHHCCHHHC
IDFVVSNELLVEDGYLLGEVVGPVTQSDSKAKVFEELAQLYNVRPEQCVVVGDGANDACI
EEEEEECCEEEECCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEE
FEIAGFAIAFNPKPILREYADVVITVKDLRAVIPVLESLSYQCCNQAQHVDIEHY
EEEECEEEEECCCHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 11342136; 12051918 [H]