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The map label for this gene is divK [H]

Identifier: 21227170

GI number: 21227170

Start: 1251832

End: 1252203

Strand: Reverse

Name: divK [H]

Synonym: MM_1068

Alternate gene names: 21227170

Gene position: 1252203-1251832 (Counterclockwise)

Preceding gene: 21227171

Following gene: 21227159

Centisome position: 30.57

GC content: 41.67

Gene sequence:

>372_bases
TTGATGATGAAAGAAATTCTTATTGTAGAAGATAACCCCATGAACATGGAATTGATCCTTGACCTCCTGGAGTTTTACGG
GCACCGTGTAACCGAAGCTGAAGACGGGATAAAGGCTCTTGAACGCCTTGCTGAGAAAAAATTCGATCTCATACTCCTTG
ATATGCAGCTTCCTAAAATGGACGGGCTTGAGGTTCTGGAAAGGATCAAAAAGAACCCTGCGACTTCAGAGATCCCTGTG
ATAGCTGTTACAGCTCATGCCATGAAAGGAAGTGAAGAACACTTTATCGAAATGGGATGCGTCGATTATATTTCAAAACC
CATAGATATTCACAGGTTCAGGTCACTTATCGATAAATACCTTGGAGAATAA

Upstream 100 bases:

>100_bases
TGGAGAATTCAAAGGAAGTCTCTTTCTATTATGAAAAAAGAAGCTTTCAAAAGAAAAGAATTAATTAATAAGATAAAACA
ATTAGCTATGCTGAAGAGGC

Downstream 100 bases:

>100_bases
TGGAAAGAAGAAAGGATTCAGCCTGAATATTCCGGAGCTATGGACCGGTATCTTCTTAAAAAACTGTTAAGGTTTTGTAA
ATTTTTATAAACTGTGCATG

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MMMKEILIVEDNPMNMELILDLLEFYGHRVTEAEDGIKALERLAEKKFDLILLDMQLPKMDGLEVLERIKKNPATSEIPV
IAVTAHAMKGSEEHFIEMGCVDYISKPIDIHRFRSLIDKYLGE

Sequences:

>Translated_123_residues
MMMKEILIVEDNPMNMELILDLLEFYGHRVTEAEDGIKALERLAEKKFDLILLDMQLPKMDGLEVLERIKKNPATSEIPV
IAVTAHAMKGSEEHFIEMGCVDYISKPIDIHRFRSLIDKYLGE
>Mature_123_residues
MMMKEILIVEDNPMNMELILDLLEFYGHRVTEAEDGIKALERLAEKKFDLILLDMQLPKMDGLEVLERIKKNPATSEIPV
IAVTAHAMKGSEEHFIEMGCVDYISKPIDIHRFRSLIDKYLGE

Specific function: Essential protein that is involved in the control of cell division, probably through the regulation of ctrA. Its phosphorylation status is regulated by PdhS [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm. Note=Localized at one pole of the cell. Colocalizes with pdhS (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=115, Percent_Identity=43.4782608695652, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI145693157, Length=115, Percent_Identity=33.9130434782609, Blast_Score=75, Evalue=9e-16,
Organism=Escherichia coli, GI1790437, Length=119, Percent_Identity=34.453781512605, Blast_Score=73, Evalue=5e-15,
Organism=Escherichia coli, GI1786599, Length=108, Percent_Identity=37.037037037037, Blast_Score=70, Evalue=5e-14,
Organism=Escherichia coli, GI48994928, Length=117, Percent_Identity=35.042735042735, Blast_Score=68, Evalue=2e-13,
Organism=Escherichia coli, GI1788191, Length=116, Percent_Identity=32.7586206896552, Blast_Score=68, Evalue=2e-13,
Organism=Escherichia coli, GI1790299, Length=119, Percent_Identity=33.6134453781513, Blast_Score=63, Evalue=5e-12,
Organism=Escherichia coli, GI1788713, Length=110, Percent_Identity=30, Blast_Score=63, Evalue=6e-12,
Organism=Escherichia coli, GI1786911, Length=108, Percent_Identity=36.1111111111111, Blast_Score=62, Evalue=9e-12,
Organism=Escherichia coli, GI1787487, Length=118, Percent_Identity=30.5084745762712, Blast_Score=60, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=116, Percent_Identity=28.448275862069, Blast_Score=65, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=122, Percent_Identity=29.5081967213115, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 14175; Mature: 14175

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
7.3 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
7.3 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMMKEILIVEDNPMNMELILDLLEFYGHRVTEAEDGIKALERLAEKKFDLILLDMQLPKM
CCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCC
DGLEVLERIKKNPATSEIPVIAVTAHAMKGSEEHFIEMGCVDYISKPIDIHRFRSLIDKY
CCHHHHHHHHCCCCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LGE
HCC
>Mature Secondary Structure
MMMKEILIVEDNPMNMELILDLLEFYGHRVTEAEDGIKALERLAEKKFDLILLDMQLPKM
CCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCC
DGLEVLERIKKNPATSEIPVIAVTAHAMKGSEEHFIEMGCVDYISKPIDIHRFRSLIDKY
CCHHHHHHHHCCCCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LGE
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA