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The map label for this gene is hdrC

Identifier: 21227081

GI number: 21227081

Start: 1159538

End: 1160023

Strand: Direct

Name: hdrC

Synonym: MM_0979

Alternate gene names: 21227081

Gene position: 1159538-1160023 (Clockwise)

Preceding gene: 21227080

Following gene: 21227082

Centisome position: 28.31

GC content: 53.09

Gene sequence:

>486_bases
ATGAGCGAAGAACTGCTAAAAGTGTTAAAGGCTGCGGGACTGGACGTGCTTTCCTGCATGCATTGCGGCACATGCACAGG
AAGCTGCCCTTCGGGACGGCATACCGGGCTTAATACCCGAAGAATAATTCGGGACGCACGCAAGAACAGAGCTACTGTTC
TGTCAGATGATGCCCTCTGGCTCTGTACAACCTGCTACACCTGCCAGGAGCGCTGCCCGCGCGGAATACCTATCACAGAT
GCCCTTCTTGAGCTCAGGAGGCTGGCAGTAAGAAAGGGATTTATGCGCCCTGAACACCGCCGCGTCTCGGAATTGGTGCT
TGAATGCGGACACGCAGTCCCCCTTGACGAAGAGACAAAGAAAAAGAGAGAGGAACTCGGGCTGGACCCCATACCTGAAA
CTGTCCAGAAGTATCCTGAAGCTCTTGAGGAACTGAAGGCTCTCCTCAAAACCTGCAAATTCGATGAACTGGCAGCTGAA
AAGTAA

Upstream 100 bases:

>100_bases
TCAGGATCTGGCTGCAGAGTTTCTTCCTTACCTGCTTCTTTCGGTTACACTTATTTTTTAAAAAGGAAAAAATCAATCGA
AAACCAGACAGTGAATCTGT

Downstream 100 bases:

>100_bases
GGAGGCAGAAGTAATGAACAAATTATCGCTATTCCTTGGCTGTATCGTACCCAACCGCTATCCCGGAATTGAAAAAGCAA
CCAAACTCTGCCTGCAGAGG

Product: heterodisulfide reductase subunit HDRC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MSEELLKVLKAAGLDVLSCMHCGTCTGSCPSGRHTGLNTRRIIRDARKNRATVLSDDALWLCTTCYTCQERCPRGIPITD
ALLELRRLAVRKGFMRPEHRRVSELVLECGHAVPLDEETKKKREELGLDPIPETVQKYPEALEELKALLKTCKFDELAAE
K

Sequences:

>Translated_161_residues
MSEELLKVLKAAGLDVLSCMHCGTCTGSCPSGRHTGLNTRRIIRDARKNRATVLSDDALWLCTTCYTCQERCPRGIPITD
ALLELRRLAVRKGFMRPEHRRVSELVLECGHAVPLDEETKKKREELGLDPIPETVQKYPEALEELKALLKTCKFDELAAE
K
>Mature_160_residues
SEELLKVLKAAGLDVLSCMHCGTCTGSCPSGRHTGLNTRRIIRDARKNRATVLSDDALWLCTTCYTCQERCPRGIPITDA
LLELRRLAVRKGFMRPEHRRVSELVLECGHAVPLDEETKKKREELGLDPIPETVQKYPEALEELKALLKTCKFDELAAEK

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B)

COG id: COG1150

COG function: function code C; Heterodisulfide reductase, subunit C

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HDRC_METMA (Q8PY84)

Other databases:

- EMBL:   AE008384
- RefSeq:   NP_633003.1
- ProteinModelPortal:   Q8PY84
- SMR:   Q8PY84
- GeneID:   1479321
- GenomeReviews:   AE008384_GR
- KEGG:   mma:MM_0979
- NMPDR:   fig|192952.1.peg.979
- HOGENOM:   HBG542047
- OMA:   KTGHAVP
- ProtClustDB:   CLSK569052
- BioCyc:   MMAZ192952:MM0979-MONOMER
- BRENDA:   1.8.98.1
- GO:   GO:0015948
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR017680
- InterPro:   IPR012285
- InterPro:   IPR009051
- Gene3D:   G3DSA:1.10.1060.10
- TIGRFAMs:   TIGR03290

Pfam domain/function: SSF46548 Helical_ferredxn

EC number: =1.8.98.1

Molecular weight: Translated: 18120; Mature: 17989

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS00198 4FE4S_FER_1; PS51379 4FE4S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
6.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEELLKVLKAAGLDVLSCMHCGTCTGSCPSGRHTGLNTRRIIRDARKNRATVLSDDALW
CCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCHHH
LCTTCYTCQERCPRGIPITDALLELRRLAVRKGFMRPEHRRVSELVLECGHAVPLDEETK
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHH
KKREELGLDPIPETVQKYPEALEELKALLKTCKFDELAAEK
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
>Mature Secondary Structure 
SEELLKVLKAAGLDVLSCMHCGTCTGSCPSGRHTGLNTRRIIRDARKNRATVLSDDALW
CHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCHHH
LCTTCYTCQERCPRGIPITDALLELRRLAVRKGFMRPEHRRVSELVLECGHAVPLDEETK
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHH
KKREELGLDPIPETVQKYPEALEELKALLKTCKFDELAAEK
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824