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The map label for this gene is paaK [H]

Identifier: 21226945

GI number: 21226945

Start: 998563

End: 999921

Strand: Reverse

Name: paaK [H]

Synonym: MM_0843

Alternate gene names: 21226945

Gene position: 999921-998563 (Counterclockwise)

Preceding gene: 21226946

Following gene: 21226944

Centisome position: 24.41

GC content: 47.02

Gene sequence:

>1359_bases
TTGGACAGCTCAGATCTTTATTTTAATTTCGAAATTGAAACAATGGACAGGGGAGAACTCGATGCTCTTGTCGAGGAACG
GGTGCGGTATACAGTAAGATATGCGGCTGAGAATTCCCCTTTTTACAGGAAATGGTTTGAAAAGCATGGGGTAAACCCGG
GAGATATCAAAGCCCATGAAGACCTCCTCGAACTCCCGATTATCTCCGGGGAAACAATCCGGGAAAACCAGCCCCCTGAA
ACAAAGGAGTTTATGTTCAGGAGTGCTGGCTGGGAAGATGTTTTTACGATTCACGAGACCAGCGGGACGAGCGGGACTCC
AAAGAGCTTTTTCCTTACATGGGAAGACTGGGAACGTTACGCGGAAAAATACGCCCGGATTTTCAGGTCCCAGGGCTTCG
GAAAAGGAGACAGGGTAGTTGTCTGTGCCTCTTACGGCATGAATGTGGGGGCAAACACAATGACTCTTGCTGCCAGGCAG
GTGGGCATGAGCATTATCCCTGAAGGTAAATGCACCTTTCCCCTCCGTGTTATTGAAACCTACAAACCGACAGGCATAGT
AGGAAGCGTATTCAAACTCCTGAACCTTGCCCGCAGAATGAAGGCTGAAGGAATTGACCCCCAGAATTCAGGCGTAAACA
AGCTTGTTGTGGGAGGCGAATCCTTTGCTGAAGAATCAAGAAACTATCTCTCTGAGATTTGGGGCTGCCCCGTATACAAT
ACCTATGGAAGCACGGAAGGGACCATGTGTGGAGAATGCAGTGAAATATCAGGGCTTCACGTCCCCGAAGATTTTGTTCA
TCTTGATGTTTACGACCCGCATGTAAAGGAATTCGTGCCTGAAGGAGAATGCGGAAGAGTTGTCCTGAGCACACTTCTTC
CTGTGGGGGCAAAAGCAGGAAACCTGCTTTTAAATTACGATACTGAAGATACTACAGTTGTTCTTACGCGCAAAAAATGT
GCCTGTGGAAGGACTCACATGAAAATCCTTACCCCGCAGAGAGAGGCAGAAACAGTCTGGGTTGAAGGCGCTCCTTTTAA
CCGTGTGGATGTGGAAAAAGGAGTCTTTCAGAGTGGAAATATGGAATACCTTACAGGAGAATACGAGGCTTTTCTTTACG
GCACGGAGGACGAGGGCGAAACCGTACTCAGGGTCAGTATGGAATGCAAAAATCCTGATGCCTGCGACAGAGACCTCATA
CAGGAAAATTTTGTTCGCTCTTTCCTTAAATATAAACCTCCCCTTTCCAGGGCTTATGAAGATGGCAGTTTCAGGATTCT
CTTCAATTTTGCAGGTCCAGGAGAACTTGAGCTGTATAAAATTAAAGGAAGACCAAAAAGGCTAGTAGACAGAAGGTAA

Upstream 100 bases:

>100_bases
TTTCATAATTGAAGATTAATAATTAAAGGTTAATTTATCCTCGAAGGTAAGAAATACAGATTTTTTACATGGTTAGTGGC
TTTAGCCGGGGTGTTAAGAG

Downstream 100 bases:

>100_bases
TTTTTAATCCTGTGACTATTTTTATTTTTTGTTTATTTTTTAATTTTTTATTTTCTTTTCAATATCCTGCTTATTTATTT
GTTTTACATCCTTCTTTTTG

Product: coenzyme F390 synthetase/phenylacetyl-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MDSSDLYFNFEIETMDRGELDALVEERVRYTVRYAAENSPFYRKWFEKHGVNPGDIKAHEDLLELPIISGETIRENQPPE
TKEFMFRSAGWEDVFTIHETSGTSGTPKSFFLTWEDWERYAEKYARIFRSQGFGKGDRVVVCASYGMNVGANTMTLAARQ
VGMSIIPEGKCTFPLRVIETYKPTGIVGSVFKLLNLARRMKAEGIDPQNSGVNKLVVGGESFAEESRNYLSEIWGCPVYN
TYGSTEGTMCGECSEISGLHVPEDFVHLDVYDPHVKEFVPEGECGRVVLSTLLPVGAKAGNLLLNYDTEDTTVVLTRKKC
ACGRTHMKILTPQREAETVWVEGAPFNRVDVEKGVFQSGNMEYLTGEYEAFLYGTEDEGETVLRVSMECKNPDACDRDLI
QENFVRSFLKYKPPLSRAYEDGSFRILFNFAGPGELELYKIKGRPKRLVDRR

Sequences:

>Translated_452_residues
MDSSDLYFNFEIETMDRGELDALVEERVRYTVRYAAENSPFYRKWFEKHGVNPGDIKAHEDLLELPIISGETIRENQPPE
TKEFMFRSAGWEDVFTIHETSGTSGTPKSFFLTWEDWERYAEKYARIFRSQGFGKGDRVVVCASYGMNVGANTMTLAARQ
VGMSIIPEGKCTFPLRVIETYKPTGIVGSVFKLLNLARRMKAEGIDPQNSGVNKLVVGGESFAEESRNYLSEIWGCPVYN
TYGSTEGTMCGECSEISGLHVPEDFVHLDVYDPHVKEFVPEGECGRVVLSTLLPVGAKAGNLLLNYDTEDTTVVLTRKKC
ACGRTHMKILTPQREAETVWVEGAPFNRVDVEKGVFQSGNMEYLTGEYEAFLYGTEDEGETVLRVSMECKNPDACDRDLI
QENFVRSFLKYKPPLSRAYEDGSFRILFNFAGPGELELYKIKGRPKRLVDRR
>Mature_452_residues
MDSSDLYFNFEIETMDRGELDALVEERVRYTVRYAAENSPFYRKWFEKHGVNPGDIKAHEDLLELPIISGETIRENQPPE
TKEFMFRSAGWEDVFTIHETSGTSGTPKSFFLTWEDWERYAEKYARIFRSQGFGKGDRVVVCASYGMNVGANTMTLAARQ
VGMSIIPEGKCTFPLRVIETYKPTGIVGSVFKLLNLARRMKAEGIDPQNSGVNKLVVGGESFAEESRNYLSEIWGCPVYN
TYGSTEGTMCGECSEISGLHVPEDFVHLDVYDPHVKEFVPEGECGRVVLSTLLPVGAKAGNLLLNYDTEDTTVVLTRKKC
ACGRTHMKILTPQREAETVWVEGAPFNRVDVEKGVFQSGNMEYLTGEYEAFLYGTEDEGETVLRVSMECKNPDACDRDLI
QENFVRSFLKYKPPLSRAYEDGSFRILFNFAGPGELELYKIKGRPKRLVDRR

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=311, Percent_Identity=28.6173633440514, Blast_Score=121, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 51159; Mature: 51159

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSSDLYFNFEIETMDRGELDALVEERVRYTVRYAAENSPFYRKWFEKHGVNPGDIKAHE
CCCCCEEEEEEEEECCCCHHHHHHHHHHHEEEEEECCCCCHHHHHHHHCCCCCCCCCHHH
DLLELPIISGETIRENQPPETKEFMFRSAGWEDVFTIHETSGTSGTPKSFFLTWEDWERY
HHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEHHHHHHH
AEKYARIFRSQGFGKGDRVVVCASYGMNVGANTMTLAARQVGMSIIPEGKCTFPLRVIET
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCEECCCCCCCEEEEEEEC
YKPTGIVGSVFKLLNLARRMKAEGIDPQNSGVNKLVVGGESFAEESRNYLSEIWGCPVYN
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCC
TYGSTEGTMCGECSEISGLHVPEDFVHLDVYDPHVKEFVPEGECGRVVLSTLLPVGAKAG
CCCCCCCCCCCCHHHCCCCCCCCCEEEEEEECCHHHHHCCCCCCHHHHHHHHHCCCCCCC
NLLLNYDTEDTTVVLTRKKCACGRTHMKILTPQREAETVWVEGAPFNRVDVEKGVFQSGN
CEEEEECCCCCEEEEEECCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCHHHCCCCCCC
MEYLTGEYEAFLYGTEDEGETVLRVSMECKNPDACDRDLIQENFVRSFLKYKPPLSRAYE
EEEEECCEEEEEEECCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCC
DGSFRILFNFAGPGELELYKIKGRPKRLVDRR
CCCEEEEEEECCCCCEEEEEECCCCHHHCCCC
>Mature Secondary Structure
MDSSDLYFNFEIETMDRGELDALVEERVRYTVRYAAENSPFYRKWFEKHGVNPGDIKAHE
CCCCCEEEEEEEEECCCCHHHHHHHHHHHEEEEEECCCCCHHHHHHHHCCCCCCCCCHHH
DLLELPIISGETIRENQPPETKEFMFRSAGWEDVFTIHETSGTSGTPKSFFLTWEDWERY
HHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEHHHHHHH
AEKYARIFRSQGFGKGDRVVVCASYGMNVGANTMTLAARQVGMSIIPEGKCTFPLRVIET
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCEECCCCCCCEEEEEEEC
YKPTGIVGSVFKLLNLARRMKAEGIDPQNSGVNKLVVGGESFAEESRNYLSEIWGCPVYN
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCC
TYGSTEGTMCGECSEISGLHVPEDFVHLDVYDPHVKEFVPEGECGRVVLSTLLPVGAKAG
CCCCCCCCCCCCHHHCCCCCCCCCEEEEEEECCHHHHHCCCCCCHHHHHHHHHCCCCCCC
NLLLNYDTEDTTVVLTRKKCACGRTHMKILTPQREAETVWVEGAPFNRVDVEKGVFQSGN
CEEEEECCCCCEEEEEECCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCHHHCCCCCCC
MEYLTGEYEAFLYGTEDEGETVLRVSMECKNPDACDRDLIQENFVRSFLKYKPPLSRAYE
EEEEECCEEEEEEECCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCC
DGSFRILFNFAGPGELELYKIKGRPKRLVDRR
CCCEEEEEEECCCCCEEEEEECCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]