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The map label for this gene is pfdA [H]

Identifier: 21226911

GI number: 21226911

Start: 959610

End: 960047

Strand: Direct

Name: pfdA [H]

Synonym: MM_0809

Alternate gene names: 21226911

Gene position: 959610-960047 (Clockwise)

Preceding gene: 21226910

Following gene: 21226912

Centisome position: 23.43

GC content: 50.23

Gene sequence:

>438_bases
GTGAAGGATATGGCAGAAGTCAGTGAAGAGATCAGGAATCTGGCAGCCAGGCATCAGGAGTTCCAGAGGCAGGCTGAAGC
GCTCAGGCAGGAAATGAGCATGGTACAGGCTTCCATTGCCAGCTGCGACCAGGCCATTGCAACGATAAATGAGCTGAAAG
CAGCCTCAGAAGCTGGCAGGGCTGCAGAGACCATGGTACCGGTGGGTTTTGGCTCTTACGTTTATGCTGAGGTTAAGAAT
CCGGATAAGGTTGTTGTAAATCTCGGAGCGGGTTTCAGTGCAGAAGAAACTGCAGAGGCAGCTGTTGAGACTCTTAATCG
CCGCAAGGAGCAGCTTACAAAAATCCTTGAGCAGATGAATGCTTCACTGACTAAAATTGCACAGGGAATGCAGGCCCTTG
AAACAGAAGCTGCAAAAATTCAACCTGGCCAGGCATAA

Upstream 100 bases:

>100_bases
GCCAGAACGAAAAGAACGCAACAGATAAGACATACTCGATCTTCGGAAGCAAGCACGGCGTCAAAAGAAGCCAGATCCAG
ATCGAAAGCGTAGCTGAGGA

Downstream 100 bases:

>100_bases
ATAAGCCCTGGCTCAGGAAAAGGTTACGGATTGCAGGAATCCGGAAGCCACATTCAATGATCGAATAATATCATTAACTT
TAATTAGTTCGTAAACTTAA

Product: prefoldin subunit alpha

Products: NA

Alternate protein names: GimC subunit alpha [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MKDMAEVSEEIRNLAARHQEFQRQAEALRQEMSMVQASIASCDQAIATINELKAASEAGRAAETMVPVGFGSYVYAEVKN
PDKVVVNLGAGFSAEETAEAAVETLNRRKEQLTKILEQMNASLTKIAQGMQALETEAAKIQPGQA

Sequences:

>Translated_145_residues
MKDMAEVSEEIRNLAARHQEFQRQAEALRQEMSMVQASIASCDQAIATINELKAASEAGRAAETMVPVGFGSYVYAEVKN
PDKVVVNLGAGFSAEETAEAAVETLNRRKEQLTKILEQMNASLTKIAQGMQALETEAAKIQPGQA
>Mature_145_residues
MKDMAEVSEEIRNLAARHQEFQRQAEALRQEMSMVQASIASCDQAIATINELKAASEAGRAAETMVPVGFGSYVYAEVKN
PDKVVVNLGAGFSAEETAEAAVETLNRRKEQLTKILEQMNASLTKIAQGMQALETEAAKIQPGQA

Specific function: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding [H]

COG id: COG1730

COG function: function code O; Predicted prefoldin, molecular chaperone implicated in de novo protein folding

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prefoldin subunit alpha family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011599
- InterPro:   IPR009053
- InterPro:   IPR004127 [H]

Pfam domain/function: PF02996 Prefoldin [H]

EC number: NA

Molecular weight: Translated: 15700; Mature: 15700

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDMAEVSEEIRNLAARHQEFQRQAEALRQEMSMVQASIASCDQAIATINELKAASEAGR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
AAETMVPVGFGSYVYAEVKNPDKVVVNLGAGFSAEETAEAAVETLNRRKEQLTKILEQMN
HHHHHCCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASLTKIAQGMQALETEAAKIQPGQA
HHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKDMAEVSEEIRNLAARHQEFQRQAEALRQEMSMVQASIASCDQAIATINELKAASEAGR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
AAETMVPVGFGSYVYAEVKNPDKVVVNLGAGFSAEETAEAAVETLNRRKEQLTKILEQMN
HHHHHCCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASLTKIAQGMQALETEAAKIQPGQA
HHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]