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The map label for this gene is lolC [H]

Identifier: 21226193

GI number: 21226193

Start: 117271

End: 118449

Strand: Reverse

Name: lolC [H]

Synonym: MM_0091

Alternate gene names: 21226193

Gene position: 118449-117271 (Counterclockwise)

Preceding gene: 21226194

Following gene: 21226192

Centisome position: 2.89

GC content: 46.56

Gene sequence:

>1179_bases
GTGAATCTCATGAATTATGAACTCTTTATCGCCTTCAGGCAGATTCGGGCAAGAAAATTCCAGACTCTTCTTTCGGTAGG
AGCTATAGCCATTGCTGTAATGGTACTTACGGTTTCCCAGGCACTAATGGTGGGTTTTACAGGAGAACTTTATAAAACTA
CCGTTGACAAACTCCCGCATGTCTCGGTCTCACCTCAGGAAGGCGAGGATTATATCTATCTTTACGGGACTCTCATGGAA
AGGATCGGTACGATTGAGGGAGTCACCGCAGTTTCCCCTTTCCTTACAGGGCAGGCTTCTTTCAGGTTCAAGGACAATTC
CCTGAACGCCGAGTTAAGGGGCGTGGTTCCTTCACAGGAAAATGAAATAAGCTCTATTGAAGAAGATATTGTTGAAGGCA
GTTTCAGGGAACTGGAATTTTCAAGAAATACTGTTGTTATAGGCTCAAAACTGGCGGAAAAACTCGAAGTTAACCTTGGG
GATTCCATAGCTGTGTCTTTTCCGAACGCAAATCCCCTCTCTCTCAGGGTTGTAGGGATTTTTCATACGAGATCTCCTCT
GGATGAGTCTTTGACCTATACATCCCTTGATACTGCCCGGCGGTTCTATGATGTCCCCAATGTGGTTAACGGCGTCTGGG
TACGGCTTTCTGATTTTAACAGGGACCGTGAAGTTGCAGAGGAGATCGAAGAACTCGGTTATAATGCGAGGGGATGGACA
GAGACAAACCCTGCAATCCTACGCACGATTGCTATTGAAAGAACATCGAATAACGTTGTATACGGGCTTATTATTGTCAT
AGCTTCTTTTGGTGTGGTAAGCACCCTGAACCTTTCAGTAATAGGCGCGACAGGCCAGATAGGTATGCTCCGCGCTATGG
GCGCCCCGGTTTCAAGTATTCAGAGAATTTTCATACTCCAGAGCGGGATTCTTGGCCTTCTGGGAGCTCTTGTAGGTACT
TTTGCTGGGGTTCTCATATCCCTGGCAATAGGACAGTATGAGATTCCCTCAACGCAGGCAGATGTTTACGCTGGCATGTC
CTTTATCCCTATTGTCGTGCGGGCTCAGGACATCCTTATTATAATTCTCGCAGTTTTCCTTCTGAACCTTATTACAGGAA
TTTATCCCGCCAGGCAGGCAGCGAAGCTGGACCCTGTGAAAGCTATAAGCACAAGGTAA

Upstream 100 bases:

>100_bases
GGAATTTTAGGTATTTTCATTGTTTTTGGCTTTATTAAAAAGCTGCATTAATCAAATACGGATAAATCTCAGTGAAAATT
AGAATAAATCTCAAAAATCC

Downstream 100 bases:

>100_bases
TCATGCTGAATATCTTATCATGCGAGCCCCAAAATACTCGATTTTATGCCGGATATTCCGAAGGTCTGATGTGTACGTTA
ATAGAAAATTAAACCGCAGG

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MNLMNYELFIAFRQIRARKFQTLLSVGAIAIAVMVLTVSQALMVGFTGELYKTTVDKLPHVSVSPQEGEDYIYLYGTLME
RIGTIEGVTAVSPFLTGQASFRFKDNSLNAELRGVVPSQENEISSIEEDIVEGSFRELEFSRNTVVIGSKLAEKLEVNLG
DSIAVSFPNANPLSLRVVGIFHTRSPLDESLTYTSLDTARRFYDVPNVVNGVWVRLSDFNRDREVAEEIEELGYNARGWT
ETNPAILRTIAIERTSNNVVYGLIIVIASFGVVSTLNLSVIGATGQIGMLRAMGAPVSSIQRIFILQSGILGLLGALVGT
FAGVLISLAIGQYEIPSTQADVYAGMSFIPIVVRAQDILIIILAVFLLNLITGIYPARQAAKLDPVKAISTR

Sequences:

>Translated_392_residues
MNLMNYELFIAFRQIRARKFQTLLSVGAIAIAVMVLTVSQALMVGFTGELYKTTVDKLPHVSVSPQEGEDYIYLYGTLME
RIGTIEGVTAVSPFLTGQASFRFKDNSLNAELRGVVPSQENEISSIEEDIVEGSFRELEFSRNTVVIGSKLAEKLEVNLG
DSIAVSFPNANPLSLRVVGIFHTRSPLDESLTYTSLDTARRFYDVPNVVNGVWVRLSDFNRDREVAEEIEELGYNARGWT
ETNPAILRTIAIERTSNNVVYGLIIVIASFGVVSTLNLSVIGATGQIGMLRAMGAPVSSIQRIFILQSGILGLLGALVGT
FAGVLISLAIGQYEIPSTQADVYAGMSFIPIVVRAQDILIIILAVFLLNLITGIYPARQAAKLDPVKAISTR
>Mature_392_residues
MNLMNYELFIAFRQIRARKFQTLLSVGAIAIAVMVLTVSQALMVGFTGELYKTTVDKLPHVSVSPQEGEDYIYLYGTLME
RIGTIEGVTAVSPFLTGQASFRFKDNSLNAELRGVVPSQENEISSIEEDIVEGSFRELEFSRNTVVIGSKLAEKLEVNLG
DSIAVSFPNANPLSLRVVGIFHTRSPLDESLTYTSLDTARRFYDVPNVVNGVWVRLSDFNRDREVAEEIEELGYNARGWT
ETNPAILRTIAIERTSNNVVYGLIIVIASFGVVSTLNLSVIGATGQIGMLRAMGAPVSSIQRIFILQSGILGLLGALVGT
FAGVLISLAIGQYEIPSTQADVYAGMSFIPIVVRAQDILIIILAVFLLNLITGIYPARQAAKLDPVKAISTR

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=395, Percent_Identity=27.0886075949367, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787360, Length=406, Percent_Identity=23.1527093596059, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42774; Mature: 42774

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLMNYELFIAFRQIRARKFQTLLSVGAIAIAVMVLTVSQALMVGFTGELYKTTVDKLPH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
VSVSPQEGEDYIYLYGTLMERIGTIEGVTAVSPFLTGQASFRFKDNSLNAELRGVVPSQE
CCCCCCCCCCEEEEHHHHHHHHCCCCCHHHHHHHHCCCEEEEEECCCCCCEEEECCCCCC
NEISSIEEDIVEGSFRELEFSRNTVVIGSKLAEKLEVNLGDSIAVSFPNANPLSLRVVGI
CHHHHHHHHHHCCCHHHEECCCCEEEEEHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEE
FHTRSPLDESLTYTSLDTARRFYDVPNVVNGVWVRLSDFNRDREVAEEIEELGYNARGWT
EECCCCCCCCCCHHHHHHHHHHHCCCHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCCCC
ETNPAILRTIAIERTSNNVVYGLIIVIASFGVVSTLNLSVIGATGQIGMLRAMGAPVSSI
CCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHCCCCHHHH
QRIFILQSGILGLLGALVGTFAGVLISLAIGQYEIPSTQADVYAGMSFIPIVVRAQDILI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHCCCHHHHHHHHHHHHHH
IILAVFLLNLITGIYPARQAAKLDPVKAISTR
HHHHHHHHHHHHCCCCCHHHCCCCCCHHCCCC
>Mature Secondary Structure
MNLMNYELFIAFRQIRARKFQTLLSVGAIAIAVMVLTVSQALMVGFTGELYKTTVDKLPH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
VSVSPQEGEDYIYLYGTLMERIGTIEGVTAVSPFLTGQASFRFKDNSLNAELRGVVPSQE
CCCCCCCCCCEEEEHHHHHHHHCCCCCHHHHHHHHCCCEEEEEECCCCCCEEEECCCCCC
NEISSIEEDIVEGSFRELEFSRNTVVIGSKLAEKLEVNLGDSIAVSFPNANPLSLRVVGI
CHHHHHHHHHHCCCHHHEECCCCEEEEEHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEE
FHTRSPLDESLTYTSLDTARRFYDVPNVVNGVWVRLSDFNRDREVAEEIEELGYNARGWT
EECCCCCCCCCCHHHHHHHHHHHCCCHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCCCC
ETNPAILRTIAIERTSNNVVYGLIIVIASFGVVSTLNLSVIGATGQIGMLRAMGAPVSSI
CCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHCCCCHHHH
QRIFILQSGILGLLGALVGTFAGVLISLAIGQYEIPSTQADVYAGMSFIPIVVRAQDILI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHCCCHHHHHHHHHHHHHH
IILAVFLLNLITGIYPARQAAKLDPVKAISTR
HHHHHHHHHHHHCCCCCHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]